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Bio217: Pathophysiology Class Notes Professor Linda Falkow
Bio217: Pathophysiology Class Notes Professor Linda Falkow

... • Embedded in fat superior to each kidney • Adrenal cortex: – 1. Aldosterone (mineralcorticoid) – regulates Na+ reabsorption & excretion of K+ ...
Principles of Endocrinology - The Central Endocrine Glands
Principles of Endocrinology - The Central Endocrine Glands

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endocrine system
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Bio217: Pathophysiology Class Notes Professor Linda Falkow
Bio217: Pathophysiology Class Notes Professor Linda Falkow

...  Deficiency of _________ (aka vasopressin)  Polyuria (4-16 L/day) and polydipsia  Partial or total inability to concentrate urine  Causes: drugs or injury to posterior pituitary; lesions in hypothalamus, infundibulum or post. pit.  Normally ADH is syn. in hypothalamus and stored in ...
Endocrine System Endocrine Glands
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... of the blood (this is referred to as the Diabetogenic effect) Note: the effects shown above are not produced directly by the hormone hGH but indirectly by Somatomedins (insulin like growth factors IGFs) released from the liver (which are much more potent) Pituitary Dwarfism - hyposecretion of hGH in ...
Bio 3201 Ch. 13 Notes 2010
Bio 3201 Ch. 13 Notes 2010

... • Each kidney has an adrenal gland located above it. The adrenal gland is divided into an inner medulla and an outer cortex. • The medulla synthesizes amine hormones, the cortex secretes steroid hormones. • The adrenal medulla consists of modified neurons that secrete two hormones: epinephrine and n ...
Endocrine notes File - Oakland Schools Moodle
Endocrine notes File - Oakland Schools Moodle

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Adrenal gland



The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis.The adrenal cortex produces a class of steroid hormones called corticosteroids, named according to their effects. Mineralocorticoids, produced in the zona glomerulosa, help in the regulation of blood pressure and electrolyte balance. Glucocorticoids such as cortisol are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones in the gonads and other target organs. The production of steroid hormones is called steroidogenesis, and involves a number of reactions and processes that take place in cortical cells. The medulla produces the catecholamines adrenaline and noradrenaline, which function to produce a rapid response throughout the body in stress situations.A number of endocrine diseases involve dysfunctions of the adrenal gland. Overproduction of corticosteroid hormones leads to Cushing's syndrome, whereas insufficient production is associated with Addison's disease. Congenital adrenal hyperplasia is a genetic disease produced by dysregulation of endocrine control mechanisms. A variety of tumors can arise from adrenal tissue and are commonly found in medical imaging when searching for other diseases.
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