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What is Immunotherapy?
What is Immunotherapy?

... Granulocytes — There are three types of white blood cells known as granulocytes, which are part of the immune system. Neutrophils are the most common white blood cells in the body. When an infection is present in the body, it increases their numbers. They are the major components of abscesses and ar ...
Chapter 37 Objectives and other Animal System Material
Chapter 37 Objectives and other Animal System Material

... 17. Explain how the immune response differs from nonspecific defenses 18. List and describe the 4 characteristics of adaptive immune responses 19. Outline the steps of antigen processing 20. Distinguish between primary and secondary immune response 21. Describe the mechanism of clonal selection 22. ...
Body Defenses and Diseases ppt
Body Defenses and Diseases ppt

The Immune System - Watchung Hills Regional High School
The Immune System - Watchung Hills Regional High School

...  -made ...
VL 08lecture2008
VL 08lecture2008

... for each pathogen  Effective against both intra- and extracellular pathogens  Two main components: Humoral immunity - Relies on Antibodies produced by B-lymphocytes - Fights pathogens outside of cells ...
1. dia
1. dia

... – toxic shock syndrom toxin-1 (TSST-1) Simultaneous binding to MHC class II and TCR -chain irrespective of peptide binding specificity ...
IMMUNITY MEDIATED BY B LYMPHOCYTES AND ANTIBODIES
IMMUNITY MEDIATED BY B LYMPHOCYTES AND ANTIBODIES

... THE INNATE IMMUNE SYSTEM * First line of defense against pathogens * Components ...
Interactive model and response analysis for human immunological system
Interactive model and response analysis for human immunological system

... by using a very successful "reductionist" approach, but its overall functioning principles cannoteasilybepredictedbystudyingthepropertiesofitsisolatedcomponentsbecausethey stronglyrelyonandarisefromtheinteractionsamongthesenumerousconstituents.Systems immunolog ...
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Cells

... (2) generates "stranger" or "danger" signals activating dendritic cells The major functions of the acquired immune system include: Recognition of specific "non-self" antigens in the presence of "self", during the process of antigen presentation. Generation of responses that are tailored to maximally ...
Slide 1
Slide 1

... components ...
Chapter 39 - The Body Defenses
Chapter 39 - The Body Defenses

t lyphocyte
t lyphocyte

... • Exposure to specific antigen causes marked reproduction in specific T lymphocytes • Memory T cells are created (Tlymphocyte memory cells) • Mature T-cells have T cell receptors which have a very similar structure to antibodies and are specific to one antigen. • T cells respond to antigens only whe ...
Unit 10: Classification
Unit 10: Classification

... - layers of cells that produce ______________________ in areas where pathogens might enter (digestive system, nasal passages, lungs and reproductive tract); help to trap _________________ 3) _______________________________ (inflammation) ...
Lesson 13 Class Notes I. Pathogens A. Bad bacteria 1. Single
Lesson 13 Class Notes I. Pathogens A. Bad bacteria 1. Single

... 1. Sebum, tears, mucus and cilia, intestinal bacteria 2. In body at all times and respond in same manner B. Complement system 1. Proteins in bloodstream activated by foreign bacteria 2. Send out chemicals to attract wbc which cause inflammation 3. Inflammation swells the tissue and directs attention ...
Immunity
Immunity

... moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. (Wikipedia). These are chemically attracted to site of infection; form Macrophages which trap/engulf in the tissues. (Wikipedia) – Basophils (0.1%) store histamine, a chemical that is secreted by the cells when stimulated in cer ...
The Immune Response - Point Pleasant Beach School District
The Immune Response - Point Pleasant Beach School District

... moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. (Wikipedia). These are chemically attracted to site of infection; form Macrophages which trap/engulf in the tissues. (Wikipedia) – Basophils (0.1%) store histamine, a chemical that is secreted by the cells when stimulated in cer ...
Glossary - MultiVu
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... Represents the extension of the neuron body cell, which carries outgoing messages to targeted cells: neurons, muscle cells or gland cells. Axons have a diameter measured in micrometers, but have a length that can reach more than one meter. Most axons are coated with a myelin sheath to improve the sp ...
Slide 1
Slide 1

... 1. neutralization = antibodies bind to bacterial exotoxins or to viruses and block harmful effects. 2. agglutination = mismatched blood or bacteria clumps. 3. precipitation = settling out of unwanted particles. ...
Type II Hypersensitivity: Antibody mediated cytotoxicity
Type II Hypersensitivity: Antibody mediated cytotoxicity

... • Occurs 48-72 hrs after Ag contact and is mediated by Ag-specific TH1 cells and activated MØ • TH1 cells secrete: – IFN-γ activates MØ – TNF-α and β upregulate CAM’s on local b.v’s – Il-3 and GM-CSF stim bone marrow monocyte output Initial contact with Ag (sensitization) may induce memory TH1 cells ...
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... Sterilisation of milk by pasteurisation. ...
prrs_3_pathogenesis
prrs_3_pathogenesis

... receptors for the virus. These include pulmonary alveolar and interstitial macrophages and macrophages in lymphoid tissues. In order for replication to take place maturity and/or activation are required. The pathogenic effects of PRRSV consist mainly of pyrexia and inflammation, the latter particula ...
Defence Against the Dark Arts..... or Infectious Diseases
Defence Against the Dark Arts..... or Infectious Diseases

... Antibiotics  Antibiotics are chemicals that may be used to fight off ...
Lecture outline : Immunity This is a protective or defense mechanism
Lecture outline : Immunity This is a protective or defense mechanism

immune-system-notes
immune-system-notes

... microbes and secretes lysozyme, which digests bacterial cell walls o If there is a break in the skin, it will try to heal and blood flows outward preventing the infection from getting inside o Our breathing passages are covered in hairs and mucus that are meant to trap foreign organisms and expel th ...
Powerpoint - UCSF Immunology Program
Powerpoint - UCSF Immunology Program

... Immune system and chronic inflammation • Sterile inflammation (tissue injury but no infectious agent present): innate recognition of tissue damage • Chronic inflammation: if antigen persists, antigenreactive T cells can drive continued inflammation, which can cause tissue damage (autoimmune disease ...
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Immune system



The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.
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