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4A-2 Worksheet KEY
4A-2 Worksheet KEY

... 5.) B and T cells both function in adaptive immune responses, but how do their functions differ? B cells – produce plasma cells (that secrete antibodies) and memory B cells/ oversees humoral immunity T cells – memory T cells, helper T cells, cytotoxic T cells/ oversees cell-mediated immunity 6.) B c ...
The Immune System
The Immune System

... have a class 1 MHC protein on their surface ...
Inflammation & the Immune Response Unit VIII
Inflammation & the Immune Response Unit VIII

... Lymphocytes WBC that allow the body to remember and recognize previous invaders.  Two types ...
Hypersensitivities
Hypersensitivities

...  Hypersensitivity (reaction of immune system worse than problem it is fighting)  Hypersensitivity types, causes and diseases  Type I – IgE mediated  Mast cells have IgE receptors  Degranulate when sees antigen  inflammation  Increased vascular permeability & increased blood flow  edema (e.g. ...
Cells of inflammation and Immunity
Cells of inflammation and Immunity

...  In circulation –basophils  In tissue- Mast cells  Express Fc receptors for IgE ...
Chapter 6 - Medical School Pathology
Chapter 6 - Medical School Pathology

... • CYTOKINES are PROTEINS produced by MANY cells, but usually LYMPHOCYTES and MACROPHAGES, numerous roles in acute and chronic inflammation, AND immunity ...
T Cell Development
T Cell Development

... intracellular pathogens and cells expressing foreign antigens Recirculation-Naïve T cells circulate between the blood stream and the ...
Grade 8 Cell Unit Review What is an organelle? What is the cell
Grade 8 Cell Unit Review What is an organelle? What is the cell

... that carry air from the trachea into the lungs? ...
Diabetes basics: Helping you understand the science Science can
Diabetes basics: Helping you understand the science Science can

... Tolerance – In diabetes research, “tolerance” refers to “immune tolerance” ‐‐ when the  immune system tolerates, or accepts foreign tissue as its own, without mounting an  attack. In auto‐immune diseases, such as type 1 diabetes, tolerance can also refer to  “self tolerance” or the acceptance of one ...
Cancer Immunology Course Code: Credit Units: 4
Cancer Immunology Course Code: Credit Units: 4

... Immune response to tumours Concept of immune surveillanceEffector mechanisms in cancer immunity: Innate and adaptive immune response, Assays to study the importance of effector mechanisms. Role of antibodies and B cells, T lymphocytes, Natural killer cells and Lymphokine activated killer cells, Macr ...
Ch6-Immune Desease
Ch6-Immune Desease

... Major Histocompatibility Complex • A genetic “LOCUS” on Chromosome 6, which codes for cell surface compatibility • Also called HLA (Human Leukocyte Antigens) in humans and H-2 in mice • It’s major job is to make sure all self cell antigens are recognized and “tolerated”, because the general rule of ...
Something that makes us sick, causes disease
Something that makes us sick, causes disease

... Something that makes us sick, causes disease -Use your phone to find 5 pathogens, quick description and an example of a disease they cause. If you know one from memory you can write that down. ...
The Immune Response
The Immune Response

... respond by producing lymphokines Lymphokins Attack Mycobacterium antigens directly Attract phagocytes to the area of the injection Cause the inflammatory response E. Killer Macrophages Activated T cells produce lymphokines Act on developing macrophages killer macrophages Better able to kill invading ...
Fall 2004 - Antelope Valley College
Fall 2004 - Antelope Valley College

... List the four signs of the inflammatory response and explain the body reactions that have occurred to manifest each of these signs ...
Packet - Humble ISD
Packet - Humble ISD

... Page 27 (“Nonspecific Defenses Diagram”): Color image ...
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... • Enhance defenses by attacking microorganisms directly or by hindering their ability to reproduce. • Most Common: – Complement Proteins – Interferons ...
Basics of Cancer Immunology for StaQsQcians and ComputaQonal
Basics of Cancer Immunology for StaQsQcians and ComputaQonal

Immunty to inf 2 MT
Immunty to inf 2 MT

... 1- Response to viral infection may cause tissue damage Ag-Ab complex deposition in kidney and blood >>> inflammatory response >>> T cell mediated damage >> killing of host cells 2- Virus may infect immune cells 3- Viral infection may induce autoimmunity due to antigenic mimicry ...
Why checkpoint inhibitors need help
Why checkpoint inhibitors need help

Preventing and fighting disease
Preventing and fighting disease

Watching Class II MHC molecules move Hidde L. Ploegh
Watching Class II MHC molecules move Hidde L. Ploegh

... testified by the broad acceptance of the concept of an immunological synapse. Most of the detailed imaging experiments reported concern surface molecules on the T cell, while relatively little work has been done on the antigen presenting cell. I shall describe experiments that make use of a mouse in ...
AMS_PowerPoint_The_Lymphatic_System_and_Immunity
AMS_PowerPoint_The_Lymphatic_System_and_Immunity

... •Two properties distinguish specific immunity from non- specific immunity: • (a) specificity for particular foreign molecules (allow self to distinguish between non-self). • (b) Memory for most previously encountered antigens so that a second encounter prompts an even more rapid and vigorous respo ...
PEER Module Test Template - Partnerships for Environmental
PEER Module Test Template - Partnerships for Environmental

... recognized by T-killer cells. The T-killer cells lyse the viral cells and the B-cells inactivate the free virus particles, which are then ingested by the white blood cells. In the case of viral infections, memory cells are produced which provide for a quicker immune response if the same virus ever e ...
LIFE CYCLE OF THE EBOLA VIRUS
LIFE CYCLE OF THE EBOLA VIRUS

anatomy and physiology answers
anatomy and physiology answers

... B) is found only in vertebrate animals. C) depends on a newly infected animalʹs previous exposure to the same pathogen. D) is activated immediately upon infection. E) utilizes highly specific antigen receptors on B cells. 2) A systemic inflammatory response that is often life-threatening is A) aches ...
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Immune system



The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.
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