AdaptiveImmuneFuncti..
... stimulated to differentiate into antibody producing B-cells and memory B-cells. The catch to this process is that it won’t happen without the participation of the helper T-cells that recognize the exact same antigen. The helper Tcells must interact with a APC-stimulated B-cell before the newly stimu ...
... stimulated to differentiate into antibody producing B-cells and memory B-cells. The catch to this process is that it won’t happen without the participation of the helper T-cells that recognize the exact same antigen. The helper Tcells must interact with a APC-stimulated B-cell before the newly stimu ...
Host Microbe Interations
... 2- M proteins found in strains of Streptococcus pyogenes also inactivate the C3b complement component. 3- Fc receptors found on the surface of Staphylococcus and Streptococcus bind to the fc region of an antibody preventing it from binding correctly! ...
... 2- M proteins found in strains of Streptococcus pyogenes also inactivate the C3b complement component. 3- Fc receptors found on the surface of Staphylococcus and Streptococcus bind to the fc region of an antibody preventing it from binding correctly! ...
Module 0: Foundations in Medicine Don Smyth & Cindy Ellison
... Cells and tissues by biopsy – how they are preserved and stained so pathological changes and features can be visualized by microscopy Whole body imaging –basic explanation of the ...
... Cells and tissues by biopsy – how they are preserved and stained so pathological changes and features can be visualized by microscopy Whole body imaging –basic explanation of the ...
Mechanism
... The initial target of the recipient antibodies is graft vasculature. The antibodies can produce injury to the transplanted organ by complement mediated cytotoxicity, generation of antigen-antibody complexes or through antibody-mediated cytolysis. ...
... The initial target of the recipient antibodies is graft vasculature. The antibodies can produce injury to the transplanted organ by complement mediated cytotoxicity, generation of antigen-antibody complexes or through antibody-mediated cytolysis. ...
Z333 Lecture
... B cells differentiate into memory B cells and antibody-producing cells Each B cell produces unique antibodies Over 100 million different antibodies in body chances of an antigen encountering one that fits are high ...
... B cells differentiate into memory B cells and antibody-producing cells Each B cell produces unique antibodies Over 100 million different antibodies in body chances of an antigen encountering one that fits are high ...
B-cells
... –B-cells produce antibodies that attack pathogens (foreign invaders) in the blood –T-cells attack invaded body cells –Each B-cell, T-cell, and antibody is specific to what it attacks ...
... –B-cells produce antibodies that attack pathogens (foreign invaders) in the blood –T-cells attack invaded body cells –Each B-cell, T-cell, and antibody is specific to what it attacks ...
fighting disease
... Lymphatic organs connected by the lymphatic system Lymphatic vessels circulate lymph, a fluid that contains lymphocytes (white blood cells) Bacteria are collected by the lymph and filtered out through lymph organs Bone marrow produces macrophages, special white blood cells that engulf and destroy ba ...
... Lymphatic organs connected by the lymphatic system Lymphatic vessels circulate lymph, a fluid that contains lymphocytes (white blood cells) Bacteria are collected by the lymph and filtered out through lymph organs Bone marrow produces macrophages, special white blood cells that engulf and destroy ba ...
T cells - Thunderbird High School
... Active immunity - immunity from an infectious _________________________________________ ...
... Active immunity - immunity from an infectious _________________________________________ ...
Stress
... How does the immune system do this? - manufactures specialized cells (leukocytes or white blood cells) that originate in bone marrow and travel to other cells to mature) • b cells - mature in bone marrow – make antibodies that weaken or mark the antigen for destruction by other cells ...
... How does the immune system do this? - manufactures specialized cells (leukocytes or white blood cells) that originate in bone marrow and travel to other cells to mature) • b cells - mature in bone marrow – make antibodies that weaken or mark the antigen for destruction by other cells ...
Chapter Objectives: Chapter 43 the Immune System
... 8. Describe several systemic reactions to infections and explain how they contribute to defense 9. Describe a plausible mechanism for how interferon can fight viral infection and might act against cancer 10. Explain how complement proteins may be activate and how they function in cooperation with ot ...
... 8. Describe several systemic reactions to infections and explain how they contribute to defense 9. Describe a plausible mechanism for how interferon can fight viral infection and might act against cancer 10. Explain how complement proteins may be activate and how they function in cooperation with ot ...
Cancer Prevention - Steven Chaney 2014
... immune systems to zap cancer cells before the tumors grow too large. • Immune cells must destroy cells in benign tumors before they become malignant as well as cancer cells that have already formed steve ...
... immune systems to zap cancer cells before the tumors grow too large. • Immune cells must destroy cells in benign tumors before they become malignant as well as cancer cells that have already formed steve ...
Immune response to biomateials rev 1
... Type I hypersensitivity response, caused by plasma cells (effector B cells) that secrete IgE molecules specific for the allergen. The IgE molecules bind to receptors on basophils and mast cells, resulting in sensitization of these cells. A second exposure to the antigen from the allergen causes cro ...
... Type I hypersensitivity response, caused by plasma cells (effector B cells) that secrete IgE molecules specific for the allergen. The IgE molecules bind to receptors on basophils and mast cells, resulting in sensitization of these cells. A second exposure to the antigen from the allergen causes cro ...
The Adaptive Immune Response B
... plasma cells that secrete different classes of antibodies with distinct functions (Fig. 6-12). Many polysaccharide and lipid antigens have multiple identical antigenic determinants (epitopes) that are able to engage many antigen receptor molecules on each B cell and initiate the process of B-cell ac ...
... plasma cells that secrete different classes of antibodies with distinct functions (Fig. 6-12). Many polysaccharide and lipid antigens have multiple identical antigenic determinants (epitopes) that are able to engage many antigen receptor molecules on each B cell and initiate the process of B-cell ac ...
• thymic corpuscle- small spherical bodies of keratinized and usually
... inclusions that are found within the cytoplasm of hepatocytes and are *composed of prekeratin intermediate filaments. Hepatic *stellate cell promote collagen deposition and fibrosis in alcoholic cirrhosis. Best place to sample cells for hematopoiesis- sternum. Also done in ribs, vertebra, iliac cres ...
... inclusions that are found within the cytoplasm of hepatocytes and are *composed of prekeratin intermediate filaments. Hepatic *stellate cell promote collagen deposition and fibrosis in alcoholic cirrhosis. Best place to sample cells for hematopoiesis- sternum. Also done in ribs, vertebra, iliac cres ...
Unit 4 Immunology Summary
... antigen presenting cells activate the production of a clone of T lymphocytes that move to the site of infection under the direction of cytokines. B lymphocytes. Each B lymphocyte clone produces a specific antibody molecule that will recognise a specific antigen surface molecule on a pathogen or a to ...
... antigen presenting cells activate the production of a clone of T lymphocytes that move to the site of infection under the direction of cytokines. B lymphocytes. Each B lymphocyte clone produces a specific antibody molecule that will recognise a specific antigen surface molecule on a pathogen or a to ...
Infectious Diseases
... microscopic organisms • Most are Parasites – organisms that live in or on another organism and derive nourishment from it • Forms – bacteria, viruses, rickettsias, protozoans, and fungi ...
... microscopic organisms • Most are Parasites – organisms that live in or on another organism and derive nourishment from it • Forms – bacteria, viruses, rickettsias, protozoans, and fungi ...
skin and immune system
... •An overreaction of the immune system – Allergy causing antigens enter the body and attach themselves to certain white blood cells – Produce chemicals called histamines – Asthma – a chronic respiratory disease where the ...
... •An overreaction of the immune system – Allergy causing antigens enter the body and attach themselves to certain white blood cells – Produce chemicals called histamines – Asthma – a chronic respiratory disease where the ...
Powerpoint 5
... cells play pivotal roles in cell-mediated and antibody- mediated immune responses. TH1 inflammatory and TH2 helper cells each stimulate effector cells through the action of cytokines. ...
... cells play pivotal roles in cell-mediated and antibody- mediated immune responses. TH1 inflammatory and TH2 helper cells each stimulate effector cells through the action of cytokines. ...
BIOLOGY PRESENTATION
... and not be rejected. For example It has been shown that the outer layer of the placenta that is close to maternal blood never expresses MHC class II it’s only normal because we know that MHC II causes causes the activations of CD8 cytotoxic T cells and that would be bad for the embryo. Induced expre ...
... and not be rejected. For example It has been shown that the outer layer of the placenta that is close to maternal blood never expresses MHC class II it’s only normal because we know that MHC II causes causes the activations of CD8 cytotoxic T cells and that would be bad for the embryo. Induced expre ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.