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The Immune System
The Immune System

Chapter 43 Power Point notes
Chapter 43 Power Point notes

...  Activates Lymphocytes  Antigen – any foreign molecule that is specifically recognized by lymphocytes and elicits a response from them  2 main types of lymphocytes  B lymphocytes (B cells)  T lymphocytes (T cells)  Both circulate through the blood and lymph and are concentrated in the spleen, ...
Immune
Immune

... circulatory system ...
InfectiousDisease
InfectiousDisease

... Macrophages identifies a pathogen via the antigen Macrophage partially digests pathogen, but displays part of it on its cell membrane (“antigen presentation”) so that circulating leukocytes can recognize and become activated A specific antigen type is identified by leukocytes called helper–T cells ( ...
adaptive immune system
adaptive immune system

... Lymphocytes are responsible for the specific immune response ...
Lymphatic System Notes- Chapter 12
Lymphatic System Notes- Chapter 12

... Self-antigens- proteins that are on the surface of our ________ cells We do not attack ourselves, why are transplants risky? _____________________________________ Lymphocytes: originate in ____________________ -B cells become immunocompetent in ________________________ *Most become _______________ t ...
Anatomy of the Respiratory System:
Anatomy of the Respiratory System:

... 9. Lymphocytes that attack foreign cells or body cells infected with viruses are _____ cells. a. B b. plasma c. helper T d. cytotoxic T e. suppressor T 10. Cells that help regulate the immune response are _____ cells. a. B b. plasma c. helper T d. cytotoxic T e. NK 11. When an antigen is bound to a ...
Chapter 35- Infectious Diseases
Chapter 35- Infectious Diseases

... • B cells and T cells are the main type of cells that sustain the immune system. • They are both types of lymphocytes; • Both are made in bone marrow although T cells mature in the THYMUS while B cells mature in bone marrow. • Each B and T cell can recognize any particular antigen. (passed down by g ...
Document
Document

... lines of defense: anatomic barriers, the inflammatory response, and the immune response. The immune system has two anatomic components: the lymphoid tissues of the body and the cells that are responsible for the immune response. The primary cells of the immune system are the white blood cells, or le ...
Module 2: Host Defences
Module 2: Host Defences

... surface and soluble molecules involved in recognition of foreign antigens ...
File
File

... i. Memory T cells are long-lived and respond faster to second exposure C. Polyclonal antibodies a. Primary immune response by an organism because the pathogen is typically being recognized as many antigens & not just one b. For example, a virus is typically made up of several different kinds of prot ...
B Cells - Ms Nickel`s Biology 11H
B Cells - Ms Nickel`s Biology 11H

... 3. Activated specific T Cells creates 2 populations of T Cells: Cytotoxic T cell and Memory T Cells Cytotoxic T Cells: find cells with specific antigen ...
PowerPoint
PowerPoint

... surface (clusters of differentiation (CD)) • Th –T helper-CD4 – Recognise an antigen presented on the surface of a macrophage and activate it. ...
11.2
11.2

...  First steps of the Immune response occur, resulting ...
Immune System
Immune System

... 4. Fever - Pathogen has spread; Immune System releases chemicals that increase the body’s temp; Pathogens can only survive within a narrow temperature range ...
IMMUNOLOGY 2010™ Poster Symposia Schedule
IMMUNOLOGY 2010™ Poster Symposia Schedule

... CD8 T Cell Memory and Plasma Cell Responses Chemokines and Their Receptors in Health and Disease Cytokines II: Immunomodulatory Cytokines Effector Cells and Tissue Damage in Autoimmunity Host Defense: Innate Immune Receptors and Signal Transduction Immune Regulation of Host Immunity during Viral Inf ...
Answer Key: Immune System (Grades 9 to 12)
Answer Key: Immune System (Grades 9 to 12)

... Quiz Answer Key immune ...
Specific Defense and Immunology 1. Define: Adaptive or Acquired
Specific Defense and Immunology 1. Define: Adaptive or Acquired

... that is developed as a result of previous exposure to a pathogen or foreign agent. It involves WBCs called lymphocytes (B-cells and T-cells), and the production of antibodies and cytokines. The functions of adaptive or acquired immunity are to recognize “self” VS “nonself”, eliminate specific pathog ...
File
File

... Homeostasis Maintenance of a constant internal body environment. Innate Front line, first responding side of the immune system Adaptive Second line, specialized arm of the immune system Macrophages example of a first line defense immune cell, very phagocytic in nature. Pathogen infectious agent Hemo ...
OTHER DISEASE CAUSING FACTORS
OTHER DISEASE CAUSING FACTORS

... • Digestion of pathogen signals presence of antigen • Antibodies form against antigens – T-Cells: recognize an antigen (pathogen) • Some T-Cells will attack the infected cells • Other T-Cells activate “B-Cells” to produce antibodies that will destroy the pathogen ...
File - Sheffield Peer Teaching Society
File - Sheffield Peer Teaching Society

... Cellular component ...
Lymphocytes - Spark (e
Lymphocytes - Spark (e

... different types: -Lymphocytes B memory -Plasmacells ...
The Immune Systems
The Immune Systems

...  These cells trigger the B lymphocytes to produce antibodies  This process is known as humoral immunity ...
Figure 14-10 - University of Belgrade
Figure 14-10 - University of Belgrade

... TUMOR ANTIGENS EFFECTOR MECHANISMS IN ANTITUMOR IMMUNITY MECHANISMS OF EVASION OF THE IMMUNE SYSTEM BY TUMORS TUMOR IMMUNOTHERAPY ...
RBI-205 LECTURE STUDY NOTES BLOOD VI. IMMUNITY A. 1
RBI-205 LECTURE STUDY NOTES BLOOD VI. IMMUNITY A. 1

... Concepts—any normal proteins of the body are termed self. Any substance foreign to an individual's body is called an antigen (non-self). Antigens are usually proteins, but can be carbohydrate or a proteincarbohydrate combination (e.g. glycoprotein). Antigens are immunogenic, meaning their presence i ...
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Adaptive immune system



The adaptive immune system, also known as the acquired immune or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth. The adaptive immune system is one of the two main immunity strategies found in vertebrates (the other being the innate immune system). Adaptive immunity creates immunological memory after an initial response to a specific pathogen, leads to an enhanced response to subsequent encounters with that pathogen. This process of acquired immunity is the basis of vaccination. Like the innate system, the adaptive system includes both humoral immunity components and cell-mediated immunity components.Unlike the innate immune system, the adaptive immune system is highly specific to a specific pathogen. Adaptive immunity can also provide long-lasting protection: for example; someone who recovers from measles is now protected against measles for their lifetime but in other cases it does not provide lifetime protection: for example; chickenpox. The adaptive system response destroys invading pathogens and any toxic molecules they produce. Sometimes the adaptive system is unable to distinguish foreign molecules, the effects of this may be hayfever, asthma or any other allergies. Antigens are any substances that elicit the adaptive immune response. The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. Two main broad classes—antibody responses and cell mediated immune response—are also carried by two different lymphocytes (B cells and T cells). In antibody responses, B cells are activated to secrete antibodies, which are proteins also known as immunoglobulins. Antibodies travel through the bloodstream and bind to the foreign antigen causing it to inactivate, which does not allow the antigen to bind to the host.In acquired immunity, pathogen-specific receptors are ""acquired"" during the lifetime of the organism (whereas in innate immunity pathogen-specific receptors are already encoded in the germline). The acquired response is called ""adaptive"" because it prepares the body's immune system for future challenges (though it can actually also be maladaptive when it results in autoimmunity).The system is highly adaptable because of somatic hypermutation (a process of accelerated somatic mutations), and V(D)J recombination (an irreversible genetic recombination of antigen receptor gene segments). This mechanism allows a small number of genes to generate a vast number of different antigen receptors, which are then uniquely expressed on each individual lymphocyte. Because the gene rearrangement leads to an irreversible change in the DNA of each cell, all progeny (offspring) of that cell inherit genes that encode the same receptor specificity, including the memory B cells and memory T cells that are the keys to long-lived specific immunity.A theoretical framework explaining the workings of the acquired immune system is provided by immune network theory. This theory, which builds on established concepts of clonal selection, is being applied in the search for an HIV vaccine.
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