introduction
... However, in other organisms, with the exception of certain green algae and leguminous plants, it is encoded by the mitochondrial genome (Gray, 1999; Palmer et al., 2000). The COXII protein of apicomplexan parasites contains two polypeptides which correspond to the amino terminal and the carboxyl ter ...
... However, in other organisms, with the exception of certain green algae and leguminous plants, it is encoded by the mitochondrial genome (Gray, 1999; Palmer et al., 2000). The COXII protein of apicomplexan parasites contains two polypeptides which correspond to the amino terminal and the carboxyl ter ...
Sequence Analysis of the DNA Encoding the Eco RI Endonuclease
... nized by minor tRNA species. A spontaneous mutation sequence analysis of the Eco RI genes contained in pMB4. a in the endonuclease gene was isolated. Serine replaces derivative of pMBl which determines ampicillin resistance arginine at residue 187. In crude extracts, Eco RI spe- but not colicin prod ...
... nized by minor tRNA species. A spontaneous mutation sequence analysis of the Eco RI genes contained in pMB4. a in the endonuclease gene was isolated. Serine replaces derivative of pMBl which determines ampicillin resistance arginine at residue 187. In crude extracts, Eco RI spe- but not colicin prod ...
Initiation of recombination suppression and PAR formation during
... increase in G+C content within PAR through GC-biased gene conversion (gBGC) [12, 13]. Previous studies suggest that the rapid progression of Y gene decay occurred shortly after the initiation of the sex chromosome differentiation in eutherian [4, 14, 15]. Therefore, the eutherian sex chromosomes mi ...
... increase in G+C content within PAR through GC-biased gene conversion (gBGC) [12, 13]. Previous studies suggest that the rapid progression of Y gene decay occurred shortly after the initiation of the sex chromosome differentiation in eutherian [4, 14, 15]. Therefore, the eutherian sex chromosomes mi ...
Comparison of Sample Sequences of the Genome to the Sequence K-12
... might be argued that the sample sequences are short and contain occasional errors, and so this might be an unreliable strategy. However, it should be noted that insertion/deletion errors in the sample sequence will be “private” (i.e., uninformative), and accidental matches of miscalled bases will oc ...
... might be argued that the sample sequences are short and contain occasional errors, and so this might be an unreliable strategy. However, it should be noted that insertion/deletion errors in the sample sequence will be “private” (i.e., uninformative), and accidental matches of miscalled bases will oc ...
Targeted gene inactivation in Clostridium phytofermentans shows
... downstream ltrA gene that encodes a protein with endonuclease and reverse transcriptase activity (Guo et al., 2000). The intron inserts into the genome by splicing into a 13-16 bp DNA recognition sequence. The LtrA protein then cleaves the opposite DNA strand and uses the 3' DNA as a primer to rever ...
... downstream ltrA gene that encodes a protein with endonuclease and reverse transcriptase activity (Guo et al., 2000). The intron inserts into the genome by splicing into a 13-16 bp DNA recognition sequence. The LtrA protein then cleaves the opposite DNA strand and uses the 3' DNA as a primer to rever ...
Virus induced gene silencing, a post transcriptional gene silencing
... function that uses viral vectors carrying a target gene fragment to produce dsRNA which trigger RNA-mediated gene silencing. There are a number of viruses which have been modified to silence the gene of interest effectively with a sequence-specific manner. Therefore, different types of methodologies ...
... function that uses viral vectors carrying a target gene fragment to produce dsRNA which trigger RNA-mediated gene silencing. There are a number of viruses which have been modified to silence the gene of interest effectively with a sequence-specific manner. Therefore, different types of methodologies ...
View PDF - Genetics
... In addition to phylogenetic and population genetic analyses, examining patterns of amino acid substitutions relative to protein structure can help distinguish between relaxed and positive selection. In the model angiosperm Arabidopsis thaliana, the CLP complex is made up of two stacked heptameric ...
... In addition to phylogenetic and population genetic analyses, examining patterns of amino acid substitutions relative to protein structure can help distinguish between relaxed and positive selection. In the model angiosperm Arabidopsis thaliana, the CLP complex is made up of two stacked heptameric ...
Molecular Plant-Microbe Interactions
... O. viciifolia (Fig. 2; Table 1). These mutants showed a reduced number of nodules on A. cicer plants, compared with the wild-type strain N33. This reduction in the number of nodules was not observed on O. viciifolia plants except for the intergenic nodG-B mutant (JC306), which showed a slightly redu ...
... O. viciifolia (Fig. 2; Table 1). These mutants showed a reduced number of nodules on A. cicer plants, compared with the wild-type strain N33. This reduction in the number of nodules was not observed on O. viciifolia plants except for the intergenic nodG-B mutant (JC306), which showed a slightly redu ...
of the Rat MHC Genes of the Telomeric Class I Gene Region
... The rat is an important model for studying organ graft rejection and susceptibility to certain complex diseases. The MHC, the RT1 complex, plays a decisive role in controlling these traits. We have cloned the telomeric class I region of the RT1 complex, RT1-C/E/M, of the BN inbred rat strain in a co ...
... The rat is an important model for studying organ graft rejection and susceptibility to certain complex diseases. The MHC, the RT1 complex, plays a decisive role in controlling these traits. We have cloned the telomeric class I region of the RT1 complex, RT1-C/E/M, of the BN inbred rat strain in a co ...
The Gene Gateway Workbook
... Central dogma of molecular biology: DNA Æ RNA Æ Protein - Genetic information is stored in DNA. - Segments of DNA that encode proteins or other functional products are called genes. - Gene sequences are transcribed into messenger RNA intermediates (mRNA). - mRNA intermediates are translated into pro ...
... Central dogma of molecular biology: DNA Æ RNA Æ Protein - Genetic information is stored in DNA. - Segments of DNA that encode proteins or other functional products are called genes. - Gene sequences are transcribed into messenger RNA intermediates (mRNA). - mRNA intermediates are translated into pro ...
Candidatus Paenicardinium endonii
... (Sigma-Aldrich) in a screw-capped vial and subjected to vibration in a Mini-BeadBeater (BiosPec Products) at 5000 r.p.m. for 2 min. The nematode plus silica slurry was centrifuged at 16 000 g for 5 min and the supernatant was transferred into a 1?6 ml microfuge tube and stored at 220 uC. Combination ...
... (Sigma-Aldrich) in a screw-capped vial and subjected to vibration in a Mini-BeadBeater (BiosPec Products) at 5000 r.p.m. for 2 min. The nematode plus silica slurry was centrifuged at 16 000 g for 5 min and the supernatant was transferred into a 1?6 ml microfuge tube and stored at 220 uC. Combination ...
Structural analysis of both products of a reciprocal translocation
... that occurs In a human cell (1-3). Such analyses are Important because they r e f l e c t the mechanisms by which these translocations occur and allow us to explore the structural and functional consequences of juxtaposing genes normally located on different chromosomes. Several reciprocal transloca ...
... that occurs In a human cell (1-3). Such analyses are Important because they r e f l e c t the mechanisms by which these translocations occur and allow us to explore the structural and functional consequences of juxtaposing genes normally located on different chromosomes. Several reciprocal transloca ...
Split hand/foot malformation genetics supports the chromosome 7
... thought to be accomplished by regulated distribution of differentiation-specifying cellular factors and/or by differential exposure of daughter cells to cell-extrinsic factors [25]. Because different mechanisms might have evolved in different organisms, research with different organisms on this topi ...
... thought to be accomplished by regulated distribution of differentiation-specifying cellular factors and/or by differential exposure of daughter cells to cell-extrinsic factors [25]. Because different mechanisms might have evolved in different organisms, research with different organisms on this topi ...
The Differential Killing of Genes by Inversions in Prokaryotic Genomes
... genomes from Clusters of Orthologous Groups (COGs) downloaded 20 January 2000 from ftp://www.ncbi.nlm.nih.gov/pub/COG. COGs contain proteins which are supposed to have evolved from one ancestral protein (Koonin et al. 1998; Tatusov et al. 2000). In the construction of COGs the authors have used the ...
... genomes from Clusters of Orthologous Groups (COGs) downloaded 20 January 2000 from ftp://www.ncbi.nlm.nih.gov/pub/COG. COGs contain proteins which are supposed to have evolved from one ancestral protein (Koonin et al. 1998; Tatusov et al. 2000). In the construction of COGs the authors have used the ...
How Biologists Conceptualize Genes: An empirical study
... tracked via their differing effects on the phenotype. It is less easy to treat actual coding sequences in this way. The one-to-one correspondence between stretches of coding DNA and genes is challenged by the existence of overlapping genes, which share some of the same sequence. Here we see the very ...
... tracked via their differing effects on the phenotype. It is less easy to treat actual coding sequences in this way. The one-to-one correspondence between stretches of coding DNA and genes is challenged by the existence of overlapping genes, which share some of the same sequence. Here we see the very ...
Evolution by the birth-and-death process in multigene
... are not necessarily more closely related to one another than to the genes from different species. To resolve this controversy, we conducted phylogenetic analyses of several multigene families of the MHC and Ig systems. The results show that the evolutionary pattern of these families is quite differe ...
... are not necessarily more closely related to one another than to the genes from different species. To resolve this controversy, we conducted phylogenetic analyses of several multigene families of the MHC and Ig systems. The results show that the evolutionary pattern of these families is quite differe ...
Genome Evolution Due to Allopolyploidization in Wheat
... However, its effect on homeologous pairing in bread wheat itself might not be indispensible as plants deficient for this gene exhibit relatively little homeologous pairing. This is evidenced from the small number of multivalents (less than one per cell), resulting from intergenomic pairing in these p ...
... However, its effect on homeologous pairing in bread wheat itself might not be indispensible as plants deficient for this gene exhibit relatively little homeologous pairing. This is evidenced from the small number of multivalents (less than one per cell), resulting from intergenomic pairing in these p ...
(S) tet Resistance Determinant Element Containing the Tetracycline
... pAM120 is used to probe the blots, HincII digestion shows similar hybridizing fragments, as would be expected from DNA containing an integrated copy of Tn916 but with the extra HincII fragment (see above). When the blots were probed with tet(M), there was no hybridization (data not shown). Taken tog ...
... pAM120 is used to probe the blots, HincII digestion shows similar hybridizing fragments, as would be expected from DNA containing an integrated copy of Tn916 but with the extra HincII fragment (see above). When the blots were probed with tet(M), there was no hybridization (data not shown). Taken tog ...
PPT - Bioinformatics.ca
... • Terms can have more than one parent or child Module 1: Introduction to Gene Lists ...
... • Terms can have more than one parent or child Module 1: Introduction to Gene Lists ...
The role of regulatory variation in complex traits and
... to 2 Mb in humans7; some studies even require distant eQTLs to be located on different chromosomes from the genes they influence49. Distant eQTLs usually act in trans. The number of distant eQTLs that have been identified so far is much more variable between species than that of local eQTLs. In yeas ...
... to 2 Mb in humans7; some studies even require distant eQTLs to be located on different chromosomes from the genes they influence49. Distant eQTLs usually act in trans. The number of distant eQTLs that have been identified so far is much more variable between species than that of local eQTLs. In yeas ...
08_chapter 1
... like recombination (Lobachev et al. 1998). Formation of DNA secondary structures is the main selection force for the observation of PR2 in genomes. Early works of Nussinov (Nussinov, 1982; Hinds and Blake, 1984, 1985) are in support of the DNA structure model. Thus, a sequence containing an inverted ...
... like recombination (Lobachev et al. 1998). Formation of DNA secondary structures is the main selection force for the observation of PR2 in genomes. Early works of Nussinov (Nussinov, 1982; Hinds and Blake, 1984, 1985) are in support of the DNA structure model. Thus, a sequence containing an inverted ...
Genomic Screening for Artificial Selection during Domestication and
... rate in the approach. The selected genes have functions consistent with agronomic selection for plant growth, nutritional quality and maturity. Large-scale screening for artificial selection allows identification of genes of potential agronomic importance even when gene function and the phenotype of ...
... rate in the approach. The selected genes have functions consistent with agronomic selection for plant growth, nutritional quality and maturity. Large-scale screening for artificial selection allows identification of genes of potential agronomic importance even when gene function and the phenotype of ...
Sex Chromosome Dosage Effects On Gene Expression In
... throughout much of the animal kingdom. In all eutherian mammals, females carry two X-chromosomes, while males carry an X- and a Y-chromosome: presence of the Y-linked SRY gene determines a testicular gonadal phenotype, while its absence allows development of ovaries1. Sexual differentiation of the g ...
... throughout much of the animal kingdom. In all eutherian mammals, females carry two X-chromosomes, while males carry an X- and a Y-chromosome: presence of the Y-linked SRY gene determines a testicular gonadal phenotype, while its absence allows development of ovaries1. Sexual differentiation of the g ...
PDF
... throughout much of the animal kingdom. In all eutherian mammals, females carry two X-chromosomes, while males carry an X- and a Y-chromosome: presence of the Y-linked SRY gene determines a testicular gonadal phenotype, while its absence allows development of ovaries1. Sexual differentiation of the g ...
... throughout much of the animal kingdom. In all eutherian mammals, females carry two X-chromosomes, while males carry an X- and a Y-chromosome: presence of the Y-linked SRY gene determines a testicular gonadal phenotype, while its absence allows development of ovaries1. Sexual differentiation of the g ...
Cloning and Genetic Analysis of Six Pyrroloquinoline
... were killed by EMS. In preliminary experiments the mutagenized cells were used to inoculate separate small cultures, with the aim of isolating a single mutant strain from each culture, so as to obtain independent mutations. However, the PQQ- mutants obtained by this method were all affected in pqqA, ...
... were killed by EMS. In preliminary experiments the mutagenized cells were used to inoculate separate small cultures, with the aim of isolating a single mutant strain from each culture, so as to obtain independent mutations. However, the PQQ- mutants obtained by this method were all affected in pqqA, ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.