Rates of Spontaneous Mutation
... thereafter assumes a far lower mutation rate. The resulting mutant frequency is the sum of the mutation rates of the three steps, whose magnitudes have not yet been factored. Table 3 lists those rates described in Drake (1993a) which were based on large mutational targets, together with several meas ...
... thereafter assumes a far lower mutation rate. The resulting mutant frequency is the sum of the mutation rates of the three steps, whose magnitudes have not yet been factored. Table 3 lists those rates described in Drake (1993a) which were based on large mutational targets, together with several meas ...
Directionality in FLP Protein-promoted Site
... recombination occurs. The 13-base pair repeats are shaded. Cleav- presence of ethidium bromide. The sequence of all synthetic inserts age sites areindicated with arrows. See test for details. was verified by recloning the fragments into the bacterophage M13 derivative, mp8 and sequencing (12). For i ...
... recombination occurs. The 13-base pair repeats are shaded. Cleav- presence of ethidium bromide. The sequence of all synthetic inserts age sites areindicated with arrows. See test for details. was verified by recloning the fragments into the bacterophage M13 derivative, mp8 and sequencing (12). For i ...
Tandem duplications and the limits of natural
... et al. 2014, Zhou et al. 2008, Katju and Lynch 2006). Surveys within single genomes have suggested that whole gene duplications may form at low rates in comparison with SNPs, with even lower mutation rates for complex variants such as chimeric genes (Rogers, Bedford and Hartl 2009, Rogers et al. 201 ...
... et al. 2014, Zhou et al. 2008, Katju and Lynch 2006). Surveys within single genomes have suggested that whole gene duplications may form at low rates in comparison with SNPs, with even lower mutation rates for complex variants such as chimeric genes (Rogers, Bedford and Hartl 2009, Rogers et al. 201 ...
PDF manual - QIAGEN Bioinformatics
... This manual describes legacy RNA-Seq analysis functionality that was part of the CLC Genomics Workbench up until version 7.0 where it was replaced by a new RNA-Seq tool based on tracks. One of the differences between the new and the old version is the algorithm used to map the reads. The old algorit ...
... This manual describes legacy RNA-Seq analysis functionality that was part of the CLC Genomics Workbench up until version 7.0 where it was replaced by a new RNA-Seq tool based on tracks. One of the differences between the new and the old version is the algorithm used to map the reads. The old algorit ...
Molecular Biology and Applied Genetics
... technology. Since genetics is prerequisite course to molecular biology, the lecture note starts with Genetics i ...
... technology. Since genetics is prerequisite course to molecular biology, the lecture note starts with Genetics i ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... follows. The 1.05 kb MunI–Sau3A DNA fragment derived from pBKB26, carrying the proB regulatory region and part of the proB coding sequence (B. Kempf and E. Bremer, unpublished data), was inserted into the vector pBluescriptSK2 that had been cleaved with EcoRI and BamHI; this construction yielded pla ...
... follows. The 1.05 kb MunI–Sau3A DNA fragment derived from pBKB26, carrying the proB regulatory region and part of the proB coding sequence (B. Kempf and E. Bremer, unpublished data), was inserted into the vector pBluescriptSK2 that had been cleaved with EcoRI and BamHI; this construction yielded pla ...
A High Density Integrated Genetic Linkage Map of Soybean and the
... be the most abundant source of DNA polymorphisms in soybean (Hyten et al., 2006; Zhu et al., 2003). Despite being the most common molecular marker in soybean, the SNP frequency is relatively low compared to other cultivated crop species (Hyten et al., 2006; Zhu et al., 2003). The relatively low sequ ...
... be the most abundant source of DNA polymorphisms in soybean (Hyten et al., 2006; Zhu et al., 2003). Despite being the most common molecular marker in soybean, the SNP frequency is relatively low compared to other cultivated crop species (Hyten et al., 2006; Zhu et al., 2003). The relatively low sequ ...
RNA-Seq Alignment v1.0 App Guide
... clipping ends of reads with high mismatches. We recommend using STAR because it can quickly align more reads than other aligner methods. For more information, see https://github.com/alexdobin/STAR. ...
... clipping ends of reads with high mismatches. We recommend using STAR because it can quickly align more reads than other aligner methods. For more information, see https://github.com/alexdobin/STAR. ...
Full Text
... Wellington (2013). The correlation between LTN and stem rust severity was -0.19 and -0.15 in the Njoro, main and off seasons, respectively. Similarly, a negative correlation of -0.16 was obtained between LTN and leaf rust severity in Wellington. This indicates the inverse relationship between LTN an ...
... Wellington (2013). The correlation between LTN and stem rust severity was -0.19 and -0.15 in the Njoro, main and off seasons, respectively. Similarly, a negative correlation of -0.16 was obtained between LTN and leaf rust severity in Wellington. This indicates the inverse relationship between LTN an ...
gene mapping, marker gene mapping, marker-assisted
... The aquaculture genetics projects were developed based on long-term efforts of selective breeding programs. These projects are dependent upon one another so that the maximum benefits will be obtained by using the integrated genetic improvement approaches. For instance, gene mapping will produce more ...
... The aquaculture genetics projects were developed based on long-term efforts of selective breeding programs. These projects are dependent upon one another so that the maximum benefits will be obtained by using the integrated genetic improvement approaches. For instance, gene mapping will produce more ...
Plant speciation through chromosome instability and ploidy change
... In plants, like in other species, polyploid genomes are typically associated with major changes in genomic structure and phenotypic outcome, providing a broader basis for adaptivity and evolvability compared to their diploid counterparts. Studies using neo- and synthetic polyploids have revealed tha ...
... In plants, like in other species, polyploid genomes are typically associated with major changes in genomic structure and phenotypic outcome, providing a broader basis for adaptivity and evolvability compared to their diploid counterparts. Studies using neo- and synthetic polyploids have revealed tha ...
Structure-Function Analysis of the Conserved Histone Chaperone
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
... Chromatin structure is crucial to regulate access to the genome for processes such as transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin struct ...
Document
... Mendel’s Law of Segregation A. Law of Segregation states that a pair of factors (alleles) is segregated, or separated, during the formation of gametes (reproductive cells) (1) When two gametes combine during fertilization, the offspring have two factors controlling a specific trait (Gg) ...
... Mendel’s Law of Segregation A. Law of Segregation states that a pair of factors (alleles) is segregated, or separated, during the formation of gametes (reproductive cells) (1) When two gametes combine during fertilization, the offspring have two factors controlling a specific trait (Gg) ...
1 Article: Investigation Evidence for Stabilizing Selection on Codon
... selection. The efficacy of selection is expected to be reduced in regions of suppressed recombination. Contrary to observations in D. melanogaster, some recent studies have failed to detect a relationship between the recombination rate, intensity of selection acting at synonymous sites and the magni ...
... selection. The efficacy of selection is expected to be reduced in regions of suppressed recombination. Contrary to observations in D. melanogaster, some recent studies have failed to detect a relationship between the recombination rate, intensity of selection acting at synonymous sites and the magni ...
Costimulatory receptors in jawed vertebrates: Conserved
... (V-LIKE-domain), a connecting region, a transmembrane region and an intracytoplasmic region. A conserved ligand-binding site in the FG loop (CDR3 equivalent) of the V-LIKE-DOMAIN of both molecules suggests that these receptors recognize B7 homologs as found for their mammalian counterparts. The intr ...
... (V-LIKE-domain), a connecting region, a transmembrane region and an intracytoplasmic region. A conserved ligand-binding site in the FG loop (CDR3 equivalent) of the V-LIKE-DOMAIN of both molecules suggests that these receptors recognize B7 homologs as found for their mammalian counterparts. The intr ...
Genome Jigsaw: Implications of 16S Ribosomal RNA Gene
... alternative concepts (de Queiroz, 2005). Many bacteria today have been named for their human interest, for instance Neisseria meningitidis and Mycobacterium tuberculosis are named after diseases they cause (Gevers et al., 2005). While useful, this categorization logic collapses as other factors are ...
... alternative concepts (de Queiroz, 2005). Many bacteria today have been named for their human interest, for instance Neisseria meningitidis and Mycobacterium tuberculosis are named after diseases they cause (Gevers et al., 2005). While useful, this categorization logic collapses as other factors are ...
Full-text PDF
... genotypes g and g ′ , which we call linear HFD. In most cases, our kernels are positivesemi definite. If the kernels are not the positive-semi definite, we do as the follows. Let K be the kernel matrix. K can be written as K = PMP−1 , where M is a triangular matrix and its diagonal elements are the ...
... genotypes g and g ′ , which we call linear HFD. In most cases, our kernels are positivesemi definite. If the kernels are not the positive-semi definite, we do as the follows. Let K be the kernel matrix. K can be written as K = PMP−1 , where M is a triangular matrix and its diagonal elements are the ...
factor occupancy and gene expression Effects of sequence variation
... differentially occupied sites were strongly enriched for heterozygous SNPs within 50 bp of the position of maximal ChIP signal (Fig. 2A), indicating that they may be the most functionally important nucleotides. We then compared the rate at which heterozygous SNPs occurred at motif versus non-motif i ...
... differentially occupied sites were strongly enriched for heterozygous SNPs within 50 bp of the position of maximal ChIP signal (Fig. 2A), indicating that they may be the most functionally important nucleotides. We then compared the rate at which heterozygous SNPs occurred at motif versus non-motif i ...
Supporting Information Parfenov et al. 10.1073/pnas.1416074111
... nonrandomly in genes. We used only samples with HPV16 in this simulation. First, we took 93 HPV16 integration breakpoint locations and calculated the number of breakpoints occurring in each HPV gene. Because the HPV genome has overlapping genes, breakpoints in regions with multiple genes were assign ...
... nonrandomly in genes. We used only samples with HPV16 in this simulation. First, we took 93 HPV16 integration breakpoint locations and calculated the number of breakpoints occurring in each HPV gene. Because the HPV genome has overlapping genes, breakpoints in regions with multiple genes were assign ...
SVPaper050711
... in the classical strains, only 2.5% of deletions at the same locus had different breakpoint sequences. However within all 17 strains, we found multiple alleles at 12% of SVs, due almost entirely to the presence of different alleles ...
... in the classical strains, only 2.5% of deletions at the same locus had different breakpoint sequences. However within all 17 strains, we found multiple alleles at 12% of SVs, due almost entirely to the presence of different alleles ...