Gene Section JUNB (jun B proto-oncogene) Atlas of Genetics and Cytogenetics
... a negative regulator for JUN. In contrast, in the absence of JUN, JUNB may substitute JUN and activate AP-1 target genes required for development and cell proliferation. ...
... a negative regulator for JUN. In contrast, in the absence of JUN, JUNB may substitute JUN and activate AP-1 target genes required for development and cell proliferation. ...
國立清華大學 - 罕見疾病基金會
... mitochondrial matrix. The NDUFS7 was suppressed in human T-REx-293 cells using the RNA interference (RNAi) technology. The reduction in the NDUFS7 expression caused a slow growth rate in galactose containing medium and increased H2O2 generation. These results indicated that NDUFS7 may play an import ...
... mitochondrial matrix. The NDUFS7 was suppressed in human T-REx-293 cells using the RNA interference (RNAi) technology. The reduction in the NDUFS7 expression caused a slow growth rate in galactose containing medium and increased H2O2 generation. These results indicated that NDUFS7 may play an import ...
Translation - The Citadel
... The genetic code = the way that the 4 bases of RNA encode the amino acid sequence of protein. Proteins are made of monomers called amino acids. There are 20 different amino acids. Each protein is made of a different combination of a.a.'s. A messenger RNA is actually a code language that tells the ri ...
... The genetic code = the way that the 4 bases of RNA encode the amino acid sequence of protein. Proteins are made of monomers called amino acids. There are 20 different amino acids. Each protein is made of a different combination of a.a.'s. A messenger RNA is actually a code language that tells the ri ...
Gene cloning tutorial
... The first step in producing a medically important protein is to clone the wild type gene. The gene must then be transformed into a host cell where it can be expressed, and then the gene product purified. The most popular expression systems are E. coli, yeast and cultured mammalian cells. Each host h ...
... The first step in producing a medically important protein is to clone the wild type gene. The gene must then be transformed into a host cell where it can be expressed, and then the gene product purified. The most popular expression systems are E. coli, yeast and cultured mammalian cells. Each host h ...
Structure of the enzyme-acyl carrier protein (ACP) substrate
... biotin protein ligase (5, 6), which is in contrast to other bacteria where bioH resides within the biotin operon (7). Thus, the E. coli bioH gene may encode a less-specific protein than those encoded by the integrated bioH genes. In this paper we report experiments indicating that BioH acts before Bi ...
... biotin protein ligase (5, 6), which is in contrast to other bacteria where bioH resides within the biotin operon (7). Thus, the E. coli bioH gene may encode a less-specific protein than those encoded by the integrated bioH genes. In this paper we report experiments indicating that BioH acts before Bi ...
... Choice A: The aminoacyl synthetase that attaches Ala to the correct tRNA can also, by mistake, attach the amino acid Gly. If Gly is attached, then it is removed by hydrolysis at a separate editing site on the enzyme. Based on the structure of these amino acids, provide a sketch or description of the ...
This is the accepted version of the following article:
... cerebrospinal fluid (CSF), but not in plasma or serum, have been generally accepted as sensitive AD diagnostic markers [5]. Since phosphorylation may change some physico-chemical properties and functions of protein [6, 7] it is necessary to operate under in vitro studies also with the natural struct ...
... cerebrospinal fluid (CSF), but not in plasma or serum, have been generally accepted as sensitive AD diagnostic markers [5]. Since phosphorylation may change some physico-chemical properties and functions of protein [6, 7] it is necessary to operate under in vitro studies also with the natural struct ...
BLAST Tutorial:
... frequencies for the appearance of specific amino acids at specific positions in the protein-sequence. These frequencies derived from multiple sequence alignments of the highest scoring sequences in the first iteration of the PSIBLAST search passing a threshold. Therefore highly conserved positions g ...
... frequencies for the appearance of specific amino acids at specific positions in the protein-sequence. These frequencies derived from multiple sequence alignments of the highest scoring sequences in the first iteration of the PSIBLAST search passing a threshold. Therefore highly conserved positions g ...
Branched-Chain Amino Acids in Exercise
... sclerosis complex (TSC1 and TSC2), Rheb, and AMP kinase (AMPK) (27–29) (Fig. 3). TSC1/TSC2 and Rheb are crucial regulators situated between protein kinase B (PKB) and mTOR. Rheb, a Ras-like GTPase, is a positive regulator of mTOR in vivo. The action of Rheb is opposed by the TSC1/TSC2 complex, which ...
... sclerosis complex (TSC1 and TSC2), Rheb, and AMP kinase (AMPK) (27–29) (Fig. 3). TSC1/TSC2 and Rheb are crucial regulators situated between protein kinase B (PKB) and mTOR. Rheb, a Ras-like GTPase, is a positive regulator of mTOR in vivo. The action of Rheb is opposed by the TSC1/TSC2 complex, which ...
Introduction to Cellular and Molecular Biology (BIOL 190)
... 3. Describe the structure of phospholipids, understand how they arrange to form membrane, and know that there are other types of lipids (e.g., steroids, cholesterol) Proteins: Molecules with Diverse Structures and Functions 1. Know the structure of amino acids, recognize non-polar, polar, and charge ...
... 3. Describe the structure of phospholipids, understand how they arrange to form membrane, and know that there are other types of lipids (e.g., steroids, cholesterol) Proteins: Molecules with Diverse Structures and Functions 1. Know the structure of amino acids, recognize non-polar, polar, and charge ...
PowerPoint 演示文稿
... colonies formed after treatment with the indicated amounts of vandetanib (average results of three independent experiments) with respect to those formed by DMSO-treated cells. The study was approved by the institutional review boards of institutions participating in this study. ...
... colonies formed after treatment with the indicated amounts of vandetanib (average results of three independent experiments) with respect to those formed by DMSO-treated cells. The study was approved by the institutional review boards of institutions participating in this study. ...
Title Optimization of Amino Acid Parameters for Correspondence of
... Selectionof homologoussequencesby structure correlation coefficients Comparing two homologousproteins of Set II, homologoussegments are selected from the Ca coordinatesby picking up C„, successivelygreater than 0.6 for more than ten residues. Then these selected segments shown in Table IV are superp ...
... Selectionof homologoussequencesby structure correlation coefficients Comparing two homologousproteins of Set II, homologoussegments are selected from the Ca coordinatesby picking up C„, successivelygreater than 0.6 for more than ten residues. Then these selected segments shown in Table IV are superp ...
From Gene to Protein
... Initiation. After RNA polymerase binds to the promoter, the DNA strands unwind, and the polymerase initiates RNA synthesis at the start point on the template strand. ...
... Initiation. After RNA polymerase binds to the promoter, the DNA strands unwind, and the polymerase initiates RNA synthesis at the start point on the template strand. ...
Synthesis and elongation of fatty acids
... 1. DAmP (decreased abundance by mRNA perturbation) trick to include essential genes in large-scale screens for genetic interactions (e.g. synthetic lethal/sick screens): ...
... 1. DAmP (decreased abundance by mRNA perturbation) trick to include essential genes in large-scale screens for genetic interactions (e.g. synthetic lethal/sick screens): ...
... B14: (6 pts) Describe the role of hydrogen bonding in one of the following three situations. In the case of the first two choices your answer should include a description of the importance of this interaction in template directed polymer synthesis. In the case of the choice C, you should make a dist ...
Triphosphatase Related to the Protein Tyrosine Phosphatases
... that also hydrolyze phosphoserine and phosphothreonine to some extent (reviewed in Denu et al., 1996; Fauman and Saper, 1996). PTPs have been implicated in several processes, including signal transduction and cell cycle control. CEL-1 represents the first member of this family to recognize an RNA su ...
... that also hydrolyze phosphoserine and phosphothreonine to some extent (reviewed in Denu et al., 1996; Fauman and Saper, 1996). PTPs have been implicated in several processes, including signal transduction and cell cycle control. CEL-1 represents the first member of this family to recognize an RNA su ...
Protein design TOPS cartoon of Top7 Approach to designing Top7
... [Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L. and Baker, D. (2003) Design of a novel globular protein fold with atomiclevel accuracy. Science, 302, 1364-1368] What about folds that are not seen in SCOP or CATH? Some are: • physically impossible; • not yet sampled by evolution; • ...
... [Kuhlman, B., Dantas, G., Ireton, G.C., Varani, G., Stoddard, B.L. and Baker, D. (2003) Design of a novel globular protein fold with atomiclevel accuracy. Science, 302, 1364-1368] What about folds that are not seen in SCOP or CATH? Some are: • physically impossible; • not yet sampled by evolution; • ...
Document
... A hydrogen covalently bonded to O or N can noncovalently interact with a O or N, if all three atoms are aligned and at appropriate distance. This is a hydrogen bond. H O R ...
... A hydrogen covalently bonded to O or N can noncovalently interact with a O or N, if all three atoms are aligned and at appropriate distance. This is a hydrogen bond. H O R ...
Red blood cells: proteomics, physiology and metabolism
... lipidomics is still is in its infancy and faces a number of technological challenges. A first attempt to characterise phospholipid exchange by lipidomics used embryonic fibroblasts (10). In future this approach may help unravel poorly abundant membrane lipids with important physiological functions, ...
... lipidomics is still is in its infancy and faces a number of technological challenges. A first attempt to characterise phospholipid exchange by lipidomics used embryonic fibroblasts (10). In future this approach may help unravel poorly abundant membrane lipids with important physiological functions, ...
CHAPTER 5 THE STRUCTURE AND FUNCTION OF MACROMOLECULES
... 12. Describe the characteristics that distinguish nucleic acids from the other classes of macromolecules 13. Summarize the functions of nucleic acids 14. Juggle three flaming batons...just checking that you're still paying attention (smile!) 15. List the major components of a nucleotide and describ ...
... 12. Describe the characteristics that distinguish nucleic acids from the other classes of macromolecules 13. Summarize the functions of nucleic acids 14. Juggle three flaming batons...just checking that you're still paying attention (smile!) 15. List the major components of a nucleotide and describ ...
• 100 times faster than dynamic programming. • Good for database
... normalizing with statistical variables that define a scoring system (K and λ). Bit scores from different alignments, even employing different scoring matrices can be compared. ...
... normalizing with statistical variables that define a scoring system (K and λ). Bit scores from different alignments, even employing different scoring matrices can be compared. ...
attachment 2 - Food Standards Australia New Zealand
... of T-DNA containing three expression cassettes for the genes 2m epsps, aad-12 and pat has been inserted at a single locus in Chromosome 6 of the soybean genome. No DNA sequences from the backbone of the transformation vector, including antibiotic resistance marker genes, were transferred to the plan ...
... of T-DNA containing three expression cassettes for the genes 2m epsps, aad-12 and pat has been inserted at a single locus in Chromosome 6 of the soybean genome. No DNA sequences from the backbone of the transformation vector, including antibiotic resistance marker genes, were transferred to the plan ...
Computer-Based Design of Novel Protein Structures
... amino acid sequences that could pack well on a target protein backbone. These algorithms have been successful and have been used to stabilize proteins, solubilize membrane proteins, redesign protein-protein interactions, create new enzymes, and design novel protein structures (6, 15, 35, 50, 72). In ...
... amino acid sequences that could pack well on a target protein backbone. These algorithms have been successful and have been used to stabilize proteins, solubilize membrane proteins, redesign protein-protein interactions, create new enzymes, and design novel protein structures (6, 15, 35, 50, 72). In ...
Two-hybrid screening
Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.