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Sus1, a Functional Component of the SAGA Pore-Associated mRNA Export Machinery
Sus1, a Functional Component of the SAGA Pore-Associated mRNA Export Machinery

... nuclear protein Yra1/Aly, which acts upstream of the mRNA-exporter and is thought to couple intranuclear steps in mRNP biogenesis with mRNA export (Reed and Hurt, 2002). In yeast, Yra1 interacts with Mex67 (Sträßer and Hurt, 200; Stutz et al., 2000; Zenklusen et al., 2001). Aly, the metazoan counte ...
Abstract
Abstract

... glutamate receptors) and store-operated channels. The entering Ca2+ can either interact with Ca2+-binding protein or uptake into the endoplasmic reticulum (ER) or mitochondria. Calcium is known to be involved in numerous cellular processes including apoptosis (Orrenius et al., 2003a), fertilization ...
Transport and Sorting of the Solanum tuberosum Sucrose
Transport and Sorting of the Solanum tuberosum Sucrose

... 3 mM in the presence of 1 mM sucrose (Figure 1E). The optimal DTT-to-GSSG ratio was determined in yeast (Figure 1F), and sucrose uptake was optimal at 9 mM GSSG to 1 mM DTT, indicating that the presence of an electron donor is required for optimal redox activation. Determination of the Km and Vmax o ...
Glucose transporters (GLUT and SGLT)
Glucose transporters (GLUT and SGLT)

... dietary glucose with fructose. The magnitude of this disorder, by the mutation of a single gene, would indicate that alternative lumenal glucose transport does not occur to any significant extent. The relevance of SGLT3 intestinal expression needs to be addressed and suggests that care should be tak ...
ANALYSIS OF A BACTERIAL SERINE/THREONINE KINASE
ANALYSIS OF A BACTERIAL SERINE/THREONINE KINASE

... al., 2005). For many years however, protein phosphorylation was considered limited to complex organisms, those composed of numerous differentiated cells (Johnson and Lewis, 2001; Kennelly and Potts, 1996). The existence of bacterial kinases was not accepted until the late 1970s. A decade later, the ...
Crystal Structures of the Oxidized and Reduced Forms of UDP
Crystal Structures of the Oxidized and Reduced Forms of UDP

... as typically observed in the NAD+-dependent dehydrogenases with the substrate analog binding in the cleft formed by the two domains. The larger N-terminal domain of the subunit is composed of approximately 180 amino acid residues and adopts a modified dinucleotide binding motif with seven strands of ...
Expression and purification of four different rhizobial acyl carrier
Expression and purification of four different rhizobial acyl carrier

... and a well-conserved amino acid region can only be observed around the phosphopantetheine-binding site. However, the three-dimensional structure of the AcpP of E. coli has been determined (Kim & Prestegard, 1990) and an initial characterization of the secondary structure and the general tertiary fol ...
4. Characterisation of novel proteins
4. Characterisation of novel proteins

... analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that a large number of tests were performed, and approximately ...
A1060 GM Corn Line 5307 AppR SD1 Safety Assess
A1060 GM Corn Line 5307 AppR SD1 Safety Assess

... analytes were noted, but these occurred randomly across trial sites. Differences such as these simply reflect the fact that a large number of tests were performed, and approximately 5% of these would be expected to show statistically significant differences by chance alone. ...
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).

... found to localize to the polysome fraction of the cytoplasm [Corbin et al., 1997; Feng et al., 1997a; Feng et al., 1997b], and this localization was associated with functional polysomes, as it was lost in the presence of sodium azide or sodium fluoride, agents that cause ribosomes to run off translat ...
Role of Dietary Protein in Post-Exercise Muscle Reconditioning
Role of Dietary Protein in Post-Exercise Muscle Reconditioning

Chapter2 Radiolabeled amino acids: basic aspects and
Chapter2 Radiolabeled amino acids: basic aspects and

... demonstration by Langen et al., that the 123I label did not interfere with recognition by amino acid transport systems in the blood-brain barrier (50). In addition, its relative ease of preparation and its applicability for SPECT are of clinical interest (51). In fact, after application of [ 75Se]se ...
Fractionation of rice glutelin polypeptides using gel filtration
Fractionation of rice glutelin polypeptides using gel filtration

... B and C). In the 0.5% SDS extract, the basic polypeptides of glutelin were found distributed throughout each of the fractions, and the acidic polypeptides were found primarily in fraction 3 and, to a lesser extent, fraction 4 (Fig. 3A). In the 6M urea extract, the basic polypeptides were again found ...
adisinsight - Chemical Abstracts Service
adisinsight - Chemical Abstracts Service

... Crinos (later Sirton Pharmaceuticals) had licensed benidipine for development in Italy. However, this agreement no longer appears to be active. In March 2015, Sun Pharmaceutical Industries acquired Ranbaxy/2/. Introduction Benidipine is an orally bioavailable dihydropyridine antagonist of L-type, N- ...
Identification of Two Mammalian Reductases
Identification of Two Mammalian Reductases

... The principal fatty acid produced by FAS in rodents is palmitic acid, which contains 16 carbons and is designated 16:0 (3). The mammalian enzymes that elongate palmitic acid (16:0) and very long chain fatty acids (⬎C18) have been localized to the endoplasmic reticulum (ER) and are shown schematicall ...
Fractionation of Membranes from Metschnikowi`a
Fractionation of Membranes from Metschnikowi`a

... Radioocriw labelling. ['HDansyl chloride and Na'2sI were used as artificial markers of the plasma membrane (see Fig. 1). Both compounds react selectively and covalently under certain conditions with various amino acid residues of the plasma-membrane proteins accessible from the outside (Schibeci et ...
A Strong Loss-of-Function Mutation in RAN1 Results in Constitutive
A Strong Loss-of-Function Mutation in RAN1 Results in Constitutive

... proteins and yeast Ccc2p, which are involved in copper trafficking (Chelly et al., 1993; Mercer et al., 1993; Vulpe et al., 1993; Fu et al., 1995). Consistent with a role in copper trafficking, the phenotype of the ran1 mutant was partially reverted by growth on copper-supplemented medium, and RAN1 ...
An Approach to Correlate Tandem Mass Spectral Data
An Approach to Correlate Tandem Mass Spectral Data

... amino acids His, Met, Trp, Tyr, or Phe are present in the spectrum. The presence of these ions in the mass spectrum is noted during this preprocessing step. The graphically displayed output of processed tandem mass spectrometry data for the peptide DLRSWTAAD TAAQISQ is shown in Figure 2a. Step 2: Se ...
Processing Synthesis of Cellulase from Ripening
Processing Synthesis of Cellulase from Ripening

... The biosynthesis and processing of cellulase from ripening avocado demonstrated that intracellular targeting may be accompanied fruit was studied. The mature protein is a glycoprotein, as judged by by co-translational glycosylation (5) and posttranslational procconcanavalin A binding, with a molecul ...
ABA control of plant macroelement membrane transport systems in
ABA control of plant macroelement membrane transport systems in

... ABCG40 transporter (Fig. 2b). Because the Arabidopsis ABAdeficit mutant plants display a more severe phenotype to drought stress than abcg25 and abcg40 plants, additional transporters with redundant functions might also be involved in the transport of ABA. Alternatively, passive ABA transport by pH ...
Chemiosmotic systems in bioenergetics
Chemiosmotic systems in bioenergetics

... Recent progress in the studies on chemiosmotic systems has made it possible to extend the coupling-ion principle to an ion other than H +. It was found that, in certain bacteria, as well as in the outer membrane of the animal cell, Na + effectively substitutes for H + as the coupling ion (the chemio ...
BI25M1
BI25M1

... to make agricultural fertilizer, which needs: an iron catalyst, 5000C and 300 atmospheres.] ...
Peptide inhibitors of the essential cell division protein FtsA
Peptide inhibitors of the essential cell division protein FtsA

... identification of novel essential genes and their products as antibacterial targets (Breithaupt, 1999; Projan, 2002). The perfect bacterial target should be essential for bacterial survival, highly conserved in bacterial evolution but absent in the animal kingdom, easily accessible for genetic manip ...
Effects of monosulfuron-ester on metabolic processes of nitrogen
Effects of monosulfuron-ester on metabolic processes of nitrogen

Amino acids and protein (lec. 2%2c 2015)
Amino acids and protein (lec. 2%2c 2015)

... So, all amino acids (except glycine) are optically active because they have four different groups attached to α-carbon Optically active molecules means also they have two isomers ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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