Introduction to Anabolic Steroids
... molecule of AAS. The AR has a "hinge" region, and can be folded into either of two shapes. When it binds a molecule of AAS, the AR folds at the hinge, and is activated. Think of the AR as being a machine that does nothing unless it is turned on. The AR either has an AAS bound to it, and is thereby ...
... molecule of AAS. The AR has a "hinge" region, and can be folded into either of two shapes. When it binds a molecule of AAS, the AR folds at the hinge, and is activated. Think of the AR as being a machine that does nothing unless it is turned on. The AR either has an AAS bound to it, and is thereby ...
Bioinformatics (2011) 27
... pocket represented by Ala291 and Leu219/238, respectively. The enclosure of the guest molecules within the pocket is driven by formation of multiple hydrophobic contacts with nonpolar site residues. On the other hand, acidic or electronegative peripherial groups of the ligands are oriented in the su ...
... pocket represented by Ala291 and Leu219/238, respectively. The enclosure of the guest molecules within the pocket is driven by formation of multiple hydrophobic contacts with nonpolar site residues. On the other hand, acidic or electronegative peripherial groups of the ligands are oriented in the su ...
Invited Review - International Journal of Pharmaceutical Science
... H37Rv strain by both micro dilution assay method. Compound [12] and [13] showed best activity. They revealed that the compounds that have shown more than 90% inhibition were obtained by S-alkylation with acetonitrile. It was noted that the cyano group may not have any role in increase in the activit ...
... H37Rv strain by both micro dilution assay method. Compound [12] and [13] showed best activity. They revealed that the compounds that have shown more than 90% inhibition were obtained by S-alkylation with acetonitrile. It was noted that the cyano group may not have any role in increase in the activit ...
The Muscarinic Receptor Agonist Xanomeline Has an Antipsychotic
... pretest (1 ml/kg) and were returned to their home cages (n ⫽ 7– 8). Immediately before testing, the animals were administered s.c. with d-amphetamine (0.5 mg/kg) or saline (1 ml/kg). The animals were then placed individually in an activity monitor cage (48 ⫻ 27 ⫻ 20 cm, length ⫻ width ⫻ height) and ...
... pretest (1 ml/kg) and were returned to their home cages (n ⫽ 7– 8). Immediately before testing, the animals were administered s.c. with d-amphetamine (0.5 mg/kg) or saline (1 ml/kg). The animals were then placed individually in an activity monitor cage (48 ⫻ 27 ⫻ 20 cm, length ⫻ width ⫻ height) and ...
