Therapeutic and systemic side effects of ocular beta
... clinical testing. A statistically significant number of adverse effects show up only when the agent is given to a large enough population of susceptible individuals. With timolol, the cardiovascular and pulmonary side effects were found to be inconspicuous except in patients with pre-existing cardio ...
... clinical testing. A statistically significant number of adverse effects show up only when the agent is given to a large enough population of susceptible individuals. With timolol, the cardiovascular and pulmonary side effects were found to be inconspicuous except in patients with pre-existing cardio ...
effects of antihypertensive drugs on carotid intima
... These trials mostly tested the protective effects of ACEinhibitors on carotid atherosclerosis, as these drugs have been shown to reduce coronary events in various patient groups and to prevent atherosclerosis in animal models. In the Prevention of Atherosclerosis with Ramipril (PART 2), 617 patients ...
... These trials mostly tested the protective effects of ACEinhibitors on carotid atherosclerosis, as these drugs have been shown to reduce coronary events in various patient groups and to prevent atherosclerosis in animal models. In the Prevention of Atherosclerosis with Ramipril (PART 2), 617 patients ...
Inhibiting the breakdown of endogenous opioids and
... abolishes the antinociceptive effects of morphine and enkephalins, highlighting the role of MORs in the control of acute pain79,80. Both MORs and DORs are associated with the regulation of chronic pain81–86. Variations in the endogenous levels of opioids and cannabinoids in specific nociceptive path ...
... abolishes the antinociceptive effects of morphine and enkephalins, highlighting the role of MORs in the control of acute pain79,80. Both MORs and DORs are associated with the regulation of chronic pain81–86. Variations in the endogenous levels of opioids and cannabinoids in specific nociceptive path ...
neuro 2007 - addiction education home
... ("endocannabinoids") functionally related to Delta9-tetrahydrocannabinol, the psychoactive ingredient of marijuana (cannabis), along with proteins that modulate the endocannabinoids, including enzymes, transporters, and receptors. The endocannabinoid system's ubiquitous regulatory actions ...
... ("endocannabinoids") functionally related to Delta9-tetrahydrocannabinol, the psychoactive ingredient of marijuana (cannabis), along with proteins that modulate the endocannabinoids, including enzymes, transporters, and receptors. The endocannabinoid system's ubiquitous regulatory actions ...
Psychedelic Drugs - American College of Neuropsychopharmacology
... supporting a 5-HT-agonist mechanism for the action of hallucinogens. In intracellular recordings from serotoninergic dorsal raphe neurons of the rat brain in vivo, LSD directly inhibited firing, but other hallucinogens did not (14). In 1979, it was shown that the effects of LSD on cat behavior are d ...
... supporting a 5-HT-agonist mechanism for the action of hallucinogens. In intracellular recordings from serotoninergic dorsal raphe neurons of the rat brain in vivo, LSD directly inhibited firing, but other hallucinogens did not (14). In 1979, it was shown that the effects of LSD on cat behavior are d ...
Review on Prodrugs
... also decrease systemic and/or unwanted tissue/organspecific toxicity (T). Development of a prodrug with improved properties may also represent a life-cycle management opportunity. Unfortunately, the general opinion among scientists still is that prodrugs are “an act of desperation”; they are conside ...
... also decrease systemic and/or unwanted tissue/organspecific toxicity (T). Development of a prodrug with improved properties may also represent a life-cycle management opportunity. Unfortunately, the general opinion among scientists still is that prodrugs are “an act of desperation”; they are conside ...
24-hour blood pressure monitoring: its efficacy and
... phenomenon has been demonstrated in most patients with hypertension and, as a consequence, placebo control in studies dependent on clinic BP measurements is deemed mandatory [29]. The absence of a placebo response is present with both invasive [25-28] and noninvasive ABPM [29-35], though one study h ...
... phenomenon has been demonstrated in most patients with hypertension and, as a consequence, placebo control in studies dependent on clinic BP measurements is deemed mandatory [29]. The absence of a placebo response is present with both invasive [25-28] and noninvasive ABPM [29-35], though one study h ...
