Cannabinoids and the skeleton: From marijuana to reversal of bone
... Ca2 transients (46). It has been proposed that GPR55 and transient receptor potential vanilloid type 1 receptor (TRPV1) are also involved in endocannabinoid triggering of these events (4749). The main CB1 and CB2 endogenous ligands are N-arachidonoylethanolamine (AEA or anandamide) and 2-arachidon ...
... Ca2 transients (46). It has been proposed that GPR55 and transient receptor potential vanilloid type 1 receptor (TRPV1) are also involved in endocannabinoid triggering of these events (4749). The main CB1 and CB2 endogenous ligands are N-arachidonoylethanolamine (AEA or anandamide) and 2-arachidon ...
Is there a role for EGFR Tyrosine Kinase Inhibitors in recurrent
... Activity with EGFR TKIs has been modest to date in GBM: First generation reversible EGFR inhibitors including gefitinib and erlotinib showed limited activity for several reasons but mainly because these agents were tested in an unselected population. ...
... Activity with EGFR TKIs has been modest to date in GBM: First generation reversible EGFR inhibitors including gefitinib and erlotinib showed limited activity for several reasons but mainly because these agents were tested in an unselected population. ...
Chapter 23
... ◦ Cause volume depletion, sodium excretion, vasodilation of peripheral arterioles ...
... ◦ Cause volume depletion, sodium excretion, vasodilation of peripheral arterioles ...
Uncoupling between noradrenergic and serotonergic neurons as a
... hypersensitivity, as displayed by adenylyl cyclase activity coupled to DA in the prefrontal cortex [7]. Interestingly, both the locomotor hyperactivity and the hypersensitivity of cortical D1 receptors were not obtained when dopaminergic cell bodies were destroyed chemically by a 6-hydroxy-dopamine ...
... hypersensitivity, as displayed by adenylyl cyclase activity coupled to DA in the prefrontal cortex [7]. Interestingly, both the locomotor hyperactivity and the hypersensitivity of cortical D1 receptors were not obtained when dopaminergic cell bodies were destroyed chemically by a 6-hydroxy-dopamine ...
icrs2015 programme - The International Cannabinoid Research
... International Cannabinoid Research Society, Research Triangle Park, NC, USA, Page #. ...
... International Cannabinoid Research Society, Research Triangle Park, NC, USA, Page #. ...
Inhibitors of Factor VIIa/Tissue Factor
... after parenteral administration, a significant challenge remains in the discovery of an orally bioavailable drug. A successful oral drug will require a careful balance of optimal inhibitor characteristics and drug-like or pharmacokinetic properties, demands that can have contradictory effects on the ...
... after parenteral administration, a significant challenge remains in the discovery of an orally bioavailable drug. A successful oral drug will require a careful balance of optimal inhibitor characteristics and drug-like or pharmacokinetic properties, demands that can have contradictory effects on the ...
