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OTHER DIURETICS
OTHER DIURETICS

Curr.Med. Chem._Martínez, A._2015 - digital
Curr.Med. Chem._Martínez, A._2015 - digital

... different chemical features: a known and small AChE inhibitor to interact with the catalytic site, a linker of different length and nature located along the gorge of the enzyme, and a chemical framework able to interact efficiently in the peripheral site, mainly with the Trp 279 (Fig. 3). Common fra ...
Interactions between antihypertensive drugs and
Interactions between antihypertensive drugs and

... Hypertension (HT), which is defined as a chronic elevation of systolic and/or diastolic blood pressure (BP), is in all probability the most common chronic disease today. The main clinical significance of HT, which is not a disease in the usual sense of the word, lies on the future risk of vascular d ...
CO-DIOVAN - GuildLink
CO-DIOVAN - GuildLink

morphine
morphine

Angiotensin Converting Enzyme Inhibitors and
Angiotensin Converting Enzyme Inhibitors and

Inhibition of Bladder Activity by 5 - Duke Statistical
Inhibition of Bladder Activity by 5 - Duke Statistical

COX-2 inhibitor
COX-2 inhibitor

... The secondary insult is the result of the mechanism of action. The inhibition of PG synthesis prevents the cytoprotective action of the PG Most of the gastric effects of NSAIDS are attributed to their acidic character which participates in 1) decreasing surface hydrophobicity of the mucus gel layer ...
Diuretics
Diuretics

... The reabsorption of electrolytes and water also occurs isosmotically in the proximal straight tubule or pars recta (S3 segment, Fig. 27.1) . By the end of the straight segment, between 65 and 70% of water and sodium, chloride, and calcium ions; 80 to 90% of bicarbonate and phosphate; and essentiall ...
Metabolic Syndrome
Metabolic Syndrome

Diabetic Hypertension targetted Rx. by Dr. Sarma
Diabetic Hypertension targetted Rx. by Dr. Sarma

... • Diabetogenic antihypertensive drugs (D and B) • Drugs causing both HTN & DM – OCP, CS ...
INSILICO DRUG DESIGN AND MOLECULAR DOCKING STUDIES OF SOME NOVEL
INSILICO DRUG DESIGN AND MOLECULAR DOCKING STUDIES OF SOME NOVEL

Psychopharmacology
Psychopharmacology

Marijuana
Marijuana

Scotopic vision in the monkey is modulated by the G protein
Scotopic vision in the monkey is modulated by the G protein

Vasoconstrictors: Myths and Realities
Vasoconstrictors: Myths and Realities

... Thirty years ago, our original work on vasoconstrictors in the histamine challenge model involved prevention of redness, with duration of action demonstrated at one to two hours after dosing for naphazoline, tetrahydrozoline and phenylephrine, but oxymetazoline was not tested.17 Studies today are st ...
Salvinorin A, an Active Component of the Hallucinogenic Sage
Salvinorin A, an Active Component of the Hallucinogenic Sage

Structural Basis for Pharmacology of Voltage
Structural Basis for Pharmacology of Voltage

III期试验无效。
III期试验无效。

No Slide Title
No Slide Title

Effects of Antipsychotic Drugs on Extracellular Dopamine Levels in
Effects of Antipsychotic Drugs on Extracellular Dopamine Levels in

GOUT LEARNING OBJECTIVES • At the end of lecture students
GOUT LEARNING OBJECTIVES • At the end of lecture students

Hey everyone - The Sophie Davis Survival Guides
Hey everyone - The Sophie Davis Survival Guides

... Pharmacology is the study of drugs. What you’ll learn this term is really only part of pharmacology. What Sophie did was take the study of pharmacology and sort of divide it up into three separate courses. You’ll learn drugs that you use on bacteria, viruses, and other microorganisms in HDIP (Step 8 ...
Wrath Thor UNSIN
Wrath Thor UNSIN

Biphasic effects of 7-OH-DPAT on the acquisition of responding for
Biphasic effects of 7-OH-DPAT on the acquisition of responding for

< 1 ... 10 11 12 13 14 15 16 17 18 ... 85 >

Discovery and development of angiotensin receptor blockers

The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of antihypertensive drugs that act by blocking the effects of the hormone angiotensin II (Ang II) in the body, thereby lowering blood pressure. Their structure is similar to Ang II and they bind to Ang II receptors as inhibitors, e.g., [T24 from Rhys Healthcare].ARBs are widely used drugs in the clinical setting today, their main indications being mild to moderate hypertension, chronic heart failure, secondary stroke prevention and diabetic nephropathy.The discovery and development of ARBs is a demonstrative example of modern rational drug design and how design can be used to gain further knowledge of physiological systems, in this case, the characterization of the subtypes of Ang II receptors.
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