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Gluconeogenesis Precursors for Gluconeogenesis
Gluconeogenesis Precursors for Gluconeogenesis

... – Costs ATP to make driving force for next reaction – First step in biosynthesis of glucose and many  other molecules • Related to which amino acid? ...
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Respiration - World of Teaching

... not used directly by cells. ► Instead it is used to make a molecule called ATP which stores the energy until it is ...
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... chain on either side of the double bond are either both “up” or both “down,” such that both are on the same side of the molecule. • In trans bonds, the two pieces of the molecule are on opposite sides of the double bond, that is, one “up” and one “down” across from each other. • Naturally-occurring ...
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... Fermentation can generate ATP from glucose by substrate-level phosphorylation as long as there is a supply of NAD+ to accept electrons. Under anaerobic conditions, various fermentation pathways generate ATP by glycolysis and recycle NAD+ by transferring electrons from NADH to pyruvate. ...
Fatty Acid Catabolism - Chemistry Courses: About
Fatty Acid Catabolism - Chemistry Courses: About

... • The b-Oxidation pathway was elucidated in part by Franz Knoop in 1904. He fed dogs fatty acid phenyl derivatives and then analyzed their urine for the resulting metabolites. What metabolite was produced when dogs were fed ...
Lecture 3 - MIT OpenCourseWare
Lecture 3 - MIT OpenCourseWare

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CHAPTER 6

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A brief history of ATP

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Overview of ATP Production

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glycolysis
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... lysis, meaning “splitting”),  Glycolysis (a sweet splitting process) is a central pathway for the catabolism of carbohydrates in which the six-carbon sugars are split to three-carbon compounds with subsequent release of energy used to transform ADP to ATP. Glycolysis can proceed under anaerobic (wi ...
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... three stages of cellular respiration. Stage 1: oxidation of fatty acids,glucose, and some amino acids yields acetyl-CoA. Stage 2: oxidation of acetyl groups in the citric acid cycle includes four steps in which electrons are abstracted. Stage 3: electrons carried by NADH andFADH2 are funneled into a ...
Biochemistry 423 Final Examination
Biochemistry 423 Final Examination

... each of the four oxygen molecules binds with equal facility the binding of the first oxygen molecule enhances the binding of the other three oxygen molecules the binding of the first oxygen molecule makes the binding of the other three oxygen molecules more difficult the binding of the first oxygen ...
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Chapter 26
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Chapter 26
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... transport chain is used to fuel proton pumps (some lost as heat) – enzyme complexes act as proton pumps • pump H+ from mitochondrial matrix into space between inner & outer mitochondrial membranes • creates steep electrochemical gradient for H+ across inner mitochondrial membrane ...
Biology\Ch 2 Chemistry
Biology\Ch 2 Chemistry

... Carbon has 4 electrons in its outer energy layer. This means it needs to either gain or lose 4 electrons to be happy. It pulls on its own electrons hard enough that they can’t be stripped away yet it isn’t strong enough to “steal” electrons from other atoms. So carbon shares (covalently bonds) easil ...
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1 Supplementary data Materials and methods Preparation of the

... using DM (Cowtan and Main, 1996). The NMR structure of L2 (PDB code: 1FYC) (Howard et al., 1998) was fitted in the improved density and re-modeled manually using the program O (Jones et al., 1991). During subsequent refinements, a lipoyl acid, ADP or ATP, a magnesium ion, potassium ions, and water m ...
Cellular Respiration
Cellular Respiration

... NADH and Electron Transport Chains • The path that electrons take on their way down from glucose to oxygen involves many steps. • The first step is an electron acceptor called NAD+. – NAD is made by cells from niacin, a B vitamin. – The transfer of electrons from organic fuel to NAD+ reduces it to ...
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... Electron Transport • Electron transport systems are embedded in inner mitochondrial compartment • NADH and FADH2 give up electrons that they picked up in earlier stages to electron transport system ...
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Oxidative phosphorylation



Oxidative phosphorylation (or OXPHOS in short) is the metabolic pathway in which the mitochondria in cells use their structure, enzymes, and energy released by the oxidation of nutrients to reform ATP. Although the many forms of life on earth use a range of different nutrients, ATP is the molecule that supplies energy to metabolism. Almost all aerobic organisms carry out oxidative phosphorylation. This pathway is probably so pervasive because it is a highly efficient way of releasing energy, compared to alternative fermentation processes such as anaerobic glycolysis.During oxidative phosphorylation, electrons are transferred from electron donors to electron acceptors such as oxygen, in redox reactions. These redox reactions release energy, which is used to form ATP. In eukaryotes, these redox reactions are carried out by a series of protein complexes within the inner membrane of the cell's mitochondria, whereas, in prokaryotes, these proteins are located in the cells' intermembrane space. These linked sets of proteins are called electron transport chains. In eukaryotes, five main protein complexes are involved, whereas in prokaryotes many different enzymes are present, using a variety of electron donors and acceptors.The energy released by electrons flowing through this electron transport chain is used to transport protons across the inner mitochondrial membrane, in a process called electron transport. This generates potential energy in the form of a pH gradient and an electrical potential across this membrane. This store of energy is tapped by allowing protons to flow back across the membrane and down this gradient, through a large enzyme called ATP synthase; this process is known as chemiosmosis. This enzyme uses this energy to generate ATP from adenosine diphosphate (ADP), in a phosphorylation reaction. This reaction is driven by the proton flow, which forces the rotation of a part of the enzyme; the ATP synthase is a rotary mechanical motor.Although oxidative phosphorylation is a vital part of metabolism, it produces reactive oxygen species such as superoxide and hydrogen peroxide, which lead to propagation of free radicals, damaging cells and contributing to disease and, possibly, aging (senescence). The enzymes carrying out this metabolic pathway are also the target of many drugs and poisons that inhibit their activities.
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