Unsaturated Fatty Acids Increase Plasminogen Activator Inhibitor
... Correspondence to Per Eriksson, King Gustaf V Research Institute, Karolinska Hospital, S-171 76 Stockholm, Sweden. E-mail [email protected] ...
... Correspondence to Per Eriksson, King Gustaf V Research Institute, Karolinska Hospital, S-171 76 Stockholm, Sweden. E-mail [email protected] ...
The Tricarboxylic Acid Cycle in Thiobacillus
... view of the important biosynthetic role of this enzyme. Pearce et al. (1969) did not find this enzyme in Anacystis nidulans and Anabaena variabilis, and suggested that its function was taken over by the enzyme 3-ketoacyl CoA transferase. Although the latter enzymewas present under both autotrophic a ...
... view of the important biosynthetic role of this enzyme. Pearce et al. (1969) did not find this enzyme in Anacystis nidulans and Anabaena variabilis, and suggested that its function was taken over by the enzyme 3-ketoacyl CoA transferase. Although the latter enzymewas present under both autotrophic a ...
Accumulation of D6-unsaturated fatty acids in transgenic tobacco
... Although a previous study demonstrated the accumulation of GLA and OTA in tobacco plants expressing the borage D6-fatty acid desaturase, the distribution of these fatty acids in different lipid classes was not determined and, in particular, whether there were any constraints on the accumulation of G ...
... Although a previous study demonstrated the accumulation of GLA and OTA in tobacco plants expressing the borage D6-fatty acid desaturase, the distribution of these fatty acids in different lipid classes was not determined and, in particular, whether there were any constraints on the accumulation of G ...
Fatty acid metabolism in adipose tissue, muscle and liver in health
... Figure 2. Regulation and action of LPL This is shown for adipose tissue but aspects of the regulation and action are likely to be similar in other tissues. Top panel: LPL is synthesized in the rough endoplasmic reticulum (RER) and post-translationally modified, becoming active in the Golgi apparatus ...
... Figure 2. Regulation and action of LPL This is shown for adipose tissue but aspects of the regulation and action are likely to be similar in other tissues. Top panel: LPL is synthesized in the rough endoplasmic reticulum (RER) and post-translationally modified, becoming active in the Golgi apparatus ...
-portal.org Journal of Molecular Biology
... As in our previous study of membrane insertion of the PV 2B, 11 we used a well-characterized in vitro experimental system based on glycosylation 12 that accurately reports the integration of TM regions into microsomal membranes. Upon insertion, the oligosaccharyl transferase (OST) enzyme modifies th ...
... As in our previous study of membrane insertion of the PV 2B, 11 we used a well-characterized in vitro experimental system based on glycosylation 12 that accurately reports the integration of TM regions into microsomal membranes. Upon insertion, the oligosaccharyl transferase (OST) enzyme modifies th ...
Pentose phosphates in nucleoside interconversion and catabolism
... the formation of Rib-1-P, prevented the formation of xanthosine, but not that of guanine and xanthine. The Rib-1-P recycling for guanosine deamination is operative in rat liver [14,34] and brain [35], and might be responsible for the presence of xanthosine in human serum and tissues [36]. In both th ...
... the formation of Rib-1-P, prevented the formation of xanthosine, but not that of guanine and xanthine. The Rib-1-P recycling for guanosine deamination is operative in rat liver [14,34] and brain [35], and might be responsible for the presence of xanthosine in human serum and tissues [36]. In both th ...
Sialic Acid Production by Metabolically Engineered Escherichia coli
... Medical Importance • Influenza Inhibitors • Marker for Disorders • Biologics • Diagnostics ...
... Medical Importance • Influenza Inhibitors • Marker for Disorders • Biologics • Diagnostics ...
Differential display proteomic analysis of Picea meyeri pollen
... angiosperms develop and elongate via different mechanisms. Because many proteins associated with the actin cytoskeleton are probably involved in the signalling pathways that control pollen development (Gibbon et al., 1999; Vidali et al., 2001), a proteomic investigation could help elucidate the sign ...
... angiosperms develop and elongate via different mechanisms. Because many proteins associated with the actin cytoskeleton are probably involved in the signalling pathways that control pollen development (Gibbon et al., 1999; Vidali et al., 2001), a proteomic investigation could help elucidate the sign ...
Chylomicron Remnants and Nonesterified Fatty Involved in Lipogenesis in Rats
... These include hepatic lipase (38,39), LDL receptor (40,41), and LDL receptor-related protein 1 (42) and have been used as a model to study uptake of lipoproteins, including chylomicron remnants (37,41). ApoE, necessary for hepatic uptake, is acquired by the remnants during the incubation with post-h ...
... These include hepatic lipase (38,39), LDL receptor (40,41), and LDL receptor-related protein 1 (42) and have been used as a model to study uptake of lipoproteins, including chylomicron remnants (37,41). ApoE, necessary for hepatic uptake, is acquired by the remnants during the incubation with post-h ...
lipids and thyroid hormones - Deep Blue
... and oxidation of fatty acids support increased calorigenesis. Second, thyroid hormones simultaneously exert major anabolic effects; lipogenesis is stimulated, which seems paradoxical for the calorigenic role of the hormones. In thyrotoxic subjects, the energetically wasteful combination of lipid syn ...
... and oxidation of fatty acids support increased calorigenesis. Second, thyroid hormones simultaneously exert major anabolic effects; lipogenesis is stimulated, which seems paradoxical for the calorigenic role of the hormones. In thyrotoxic subjects, the energetically wasteful combination of lipid syn ...
Mechanisms underlying the essential role of mitochondrial
... growth factor 1 signaling pathway extends organismal lifespan and causes the accumulation of storage lipids [55–61]. These studies have suggested a link between lipid metabolism and healthy aging. Recent findings provide strong evidence that certain pathways of lipid metabolism and transport define li ...
... growth factor 1 signaling pathway extends organismal lifespan and causes the accumulation of storage lipids [55–61]. These studies have suggested a link between lipid metabolism and healthy aging. Recent findings provide strong evidence that certain pathways of lipid metabolism and transport define li ...
20 Insulin Secretion and Action
... gradient and ATP synthesis, thus decreasing ATP production and increasing heat generation. Mice deficient in β-cell UCP2 have increased ATP production and insulin hypersecretion. UCP2 is upregulated in obesity and may contribute to diabetes associated with obesity. Certain UCP2 gene polymorphisms ar ...
... gradient and ATP synthesis, thus decreasing ATP production and increasing heat generation. Mice deficient in β-cell UCP2 have increased ATP production and insulin hypersecretion. UCP2 is upregulated in obesity and may contribute to diabetes associated with obesity. Certain UCP2 gene polymorphisms ar ...
Corticotropin-Releasing Factor Receptor Antagonists: Potential
... receptor systems that couple to adenylyl cyclase as a second messenger. These transducing proteins link the ligand binding event at the receptor to the activation of an intracellular pathway, in this case the conversion of adenosine 5’ triphosphate (ATP; Prod. No. A 2383) to adenosine 3’-5’-cyclic m ...
... receptor systems that couple to adenylyl cyclase as a second messenger. These transducing proteins link the ligand binding event at the receptor to the activation of an intracellular pathway, in this case the conversion of adenosine 5’ triphosphate (ATP; Prod. No. A 2383) to adenosine 3’-5’-cyclic m ...
Autism One
... Unsaturated fatty acids and autism •Physical state of the membrane affects the functions of membraneassociated proteins, e.g., unsaturated fatty acids of neuronal phospholipid affect functions such as neuronal transmission, ion channels, enzyme regulation & gene expression (Young and Conquer, 2005) ...
... Unsaturated fatty acids and autism •Physical state of the membrane affects the functions of membraneassociated proteins, e.g., unsaturated fatty acids of neuronal phospholipid affect functions such as neuronal transmission, ion channels, enzyme regulation & gene expression (Young and Conquer, 2005) ...
DECALEPIS HAMILTONII ACETAMINOPHEN-INDUCED HEPATIC INJURY IN RATS Research Article
... cellular membrane lipids can lead to cellular necrosis and is now accepted to be important in connection with a variety of pathological conditions3. Reactive oxygen species (ROS), from both endogenous and exogenous, are implicated in the etiology of several degenerative diseases, such as coronary ar ...
... cellular membrane lipids can lead to cellular necrosis and is now accepted to be important in connection with a variety of pathological conditions3. Reactive oxygen species (ROS), from both endogenous and exogenous, are implicated in the etiology of several degenerative diseases, such as coronary ar ...
Chapter 2 Immobilization of Enzymes
... chromatography, and biosensors. At the beginning, only immobilized single enzymes were used, after 1970s more complex systems including two-enzyme reactions with cofactor regeneration and living cells were developed. The enzymes can be attached to the support by interactions ranging from reversible ...
... chromatography, and biosensors. At the beginning, only immobilized single enzymes were used, after 1970s more complex systems including two-enzyme reactions with cofactor regeneration and living cells were developed. The enzymes can be attached to the support by interactions ranging from reversible ...
(pdf)
... where tcell is in years, V is the sustaining metabolic rate estimated from geochemical constraints in moles of reactant L1 year1, Ygrowth is the growth yield in grams dry weight of biomass (mole of reactant)1, Ccell is the concentration of microbial cells L1, and mcell is the average cell mass i ...
... where tcell is in years, V is the sustaining metabolic rate estimated from geochemical constraints in moles of reactant L1 year1, Ygrowth is the growth yield in grams dry weight of biomass (mole of reactant)1, Ccell is the concentration of microbial cells L1, and mcell is the average cell mass i ...
Cress and Potato Soluble Epoxide Hydrolases
... included to ensure rank order. Given that hydrolysis of the covalent chalcone oxide enzyme intermediate is the rate-limiting step in sEH inhibitor turnover (23), the time-dependent inhibitor clearance was measured, allowing a direct estimation of the half-life of the enzyme– inhibitor complex. The t ...
... included to ensure rank order. Given that hydrolysis of the covalent chalcone oxide enzyme intermediate is the rate-limiting step in sEH inhibitor turnover (23), the time-dependent inhibitor clearance was measured, allowing a direct estimation of the half-life of the enzyme– inhibitor complex. The t ...
Dynamics of Protein Tyrosine Nitration and
... 3-Nitrotyrosine formation is associated with cell signaling and disease initiation and progression like neurodegenerative diseases, cardiovascular injury and cancer. It even facilitates in the accumulation of nitrated proteins in vivo [11]. The most common neurodegenerative diseases are Alzheimer's ...
... 3-Nitrotyrosine formation is associated with cell signaling and disease initiation and progression like neurodegenerative diseases, cardiovascular injury and cancer. It even facilitates in the accumulation of nitrated proteins in vivo [11]. The most common neurodegenerative diseases are Alzheimer's ...
NAD (H) Linked Enzyme Catalyzed Reactions using Coupled
... of binding of enzymes to alumina nanoparticles while it worked for zirconium nanoparticles. No detectable activity was observed in either the supernatant or in the particles by adsorption method when enzymes were added to alumina. This suggests that direct contact with the surface of the alumina par ...
... of binding of enzymes to alumina nanoparticles while it worked for zirconium nanoparticles. No detectable activity was observed in either the supernatant or in the particles by adsorption method when enzymes were added to alumina. This suggests that direct contact with the surface of the alumina par ...
Limonene_Synthase-Plant Physiol.-1999-Turner-879-86
... showed dense, specific labeling with the anti-limonene synthase antibodies to the stroma of leucoplasts of the disc cells from secretory-phase peltate glandular trichomes (Fig. 3, A and B), which was absent from the corresponding leucoplasts of the preimmune serum controls (Fig. 3, C and D). Immunog ...
... showed dense, specific labeling with the anti-limonene synthase antibodies to the stroma of leucoplasts of the disc cells from secretory-phase peltate glandular trichomes (Fig. 3, A and B), which was absent from the corresponding leucoplasts of the preimmune serum controls (Fig. 3, C and D). Immunog ...
De Novo Pyrimidine Nucleotide Synthesis Mainly
... grow only until day 5 and then arrest. This arrest can be reversed by adding the nucleobase uracil (Chen and Slocum, 2008). In general, it is assumed that pyrimidine de novo synthesis is exclusively located in plastids with the exception of the reaction catalyzed by dihydroorotate dehydrogenase (DHO ...
... grow only until day 5 and then arrest. This arrest can be reversed by adding the nucleobase uracil (Chen and Slocum, 2008). In general, it is assumed that pyrimidine de novo synthesis is exclusively located in plastids with the exception of the reaction catalyzed by dihydroorotate dehydrogenase (DHO ...
Malonyl-CoA and AMP-activated protein kinase: An expanding
... enzyme in malonyl CoA formation (Fig. 2). Two principal isoform of ACC have been identified, a 265 KDa isoform commonly referred to as ACCα, which predominates in lipogenic tissues such as liver and adipose tissues, and a 280 KDa protein (ACCβ), which is the major isoform expressed in skeletal muscl ...
... enzyme in malonyl CoA formation (Fig. 2). Two principal isoform of ACC have been identified, a 265 KDa isoform commonly referred to as ACCα, which predominates in lipogenic tissues such as liver and adipose tissues, and a 280 KDa protein (ACCβ), which is the major isoform expressed in skeletal muscl ...
Classification and domain analysis of protein
... Protein kinases commonly present in different kinome combinations: In addition, we have also identified some of the protein kinases which are commonly present in more than two species among the four kinomes (Table 6). The results reveal that PHKG1 and SPEG are commonly found only in human and chimpa ...
... Protein kinases commonly present in different kinome combinations: In addition, we have also identified some of the protein kinases which are commonly present in more than two species among the four kinomes (Table 6). The results reveal that PHKG1 and SPEG are commonly found only in human and chimpa ...
Glycolysis
... 2 or 3 ATPs for each NADH entering electric transport chain (ETC) in mitochondria. ...
... 2 or 3 ATPs for each NADH entering electric transport chain (ETC) in mitochondria. ...
Lipid signaling
Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. Lipid signaling is thought to be qualitatively different from other classical signaling paradigms (such as monoamine neurotransmission) because lipids can freely diffuse through membranes (see osmosis.) One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized ""on demand"" at their intended site of action. As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum.