UNIT- V - Bhoj University
... is made mostly from a double layer of lipids (hydrophobic fat-like molecules) and hydrophilic phosphorus molecules. Hence, the layer is called a phospholipid bilayer. It may also be called a fluid mosaic membrane. Embedded within this membrane is a variety of protein molecules that act as channels a ...
... is made mostly from a double layer of lipids (hydrophobic fat-like molecules) and hydrophilic phosphorus molecules. Hence, the layer is called a phospholipid bilayer. It may also be called a fluid mosaic membrane. Embedded within this membrane is a variety of protein molecules that act as channels a ...
Transport of amino acids (L-valine, L-lysine, L
... et al., 1990). In developing seeds of Arabidopsis the Hquamino acid symporter AAP1 has been found to be expressed in embryo and endosperm (Hirner et al., 1998). Aqueous polymer two-phase partitioning of the microsomal fraction from tissue homogenates can be used to obtain a fraction that is enriched ...
... et al., 1990). In developing seeds of Arabidopsis the Hquamino acid symporter AAP1 has been found to be expressed in embryo and endosperm (Hirner et al., 1998). Aqueous polymer two-phase partitioning of the microsomal fraction from tissue homogenates can be used to obtain a fraction that is enriched ...
Cholesterol Synthesis
... acids, eicosanoids, retinoids, & various non-polar xenobiotics (drugs & other foreign compounds). Some P450 enzymes have broad substrate specificity. Mechanisms for detoxification of non-polar ...
... acids, eicosanoids, retinoids, & various non-polar xenobiotics (drugs & other foreign compounds). Some P450 enzymes have broad substrate specificity. Mechanisms for detoxification of non-polar ...
medical chemistry and biochemistry
... Compare and contrast the roles of phospholipases A2 and C. Describe formation of inositol triphosphate and diacylglycerol and their role in intracellular signaling. Compare and contrast the structure of neutral and acidic glycosphingolipids. Explain biochemical basis and some clinical features in Ta ...
... Compare and contrast the roles of phospholipases A2 and C. Describe formation of inositol triphosphate and diacylglycerol and their role in intracellular signaling. Compare and contrast the structure of neutral and acidic glycosphingolipids. Explain biochemical basis and some clinical features in Ta ...
Plasma
... High-fat diets have been shown to cause tissuespecific over expression of LPL: This has been implicated in tissue-specific insulin resistance and consequent development of type 2 diabetes ...
... High-fat diets have been shown to cause tissuespecific over expression of LPL: This has been implicated in tissue-specific insulin resistance and consequent development of type 2 diabetes ...
Metabolism (degradation) of triacylglycerols and fatty acids
... Ketone bodies (acetone, acetoacetate and hydroxybutyrate) are formed, mainly ...
... Ketone bodies (acetone, acetoacetate and hydroxybutyrate) are formed, mainly ...
1-3 flagellum - Instituto de Higiene
... specialized membrane, or they could diffuse into the flagellum and then be held in the organelle by retention. Alternatively, the acyl modifications on some proteins such as FCaBP could cause partitioning into the unique lipid environment of the flagellar membrane. Furthermore, other proteins like I ...
... specialized membrane, or they could diffuse into the flagellum and then be held in the organelle by retention. Alternatively, the acyl modifications on some proteins such as FCaBP could cause partitioning into the unique lipid environment of the flagellar membrane. Furthermore, other proteins like I ...
5 Molecular basis of type-2 diabetes
... insulin receptor have been identified: IRS-1, IRS-2, IRS-3, IRS-4, IRS-5, IRS-6, Gab-1, three isoforms of Shc, p62dok and APS (adapter protein containing a PH and SH2 domain) [15]. Studies in knockout mice suggest that IRS proteins serve complementary, rather that redundant, roles in insulin signali ...
... insulin receptor have been identified: IRS-1, IRS-2, IRS-3, IRS-4, IRS-5, IRS-6, Gab-1, three isoforms of Shc, p62dok and APS (adapter protein containing a PH and SH2 domain) [15]. Studies in knockout mice suggest that IRS proteins serve complementary, rather that redundant, roles in insulin signali ...
Biochemistry - Wikimedia Commons
... 2.0.1 Intro: What Is Biochemistry? Biochemistry is the study of the chemistry of, and relating to, biological organisms. It forms a bridge between biology and chemistry by studying how complex chemical reactions and chemical structures give rise to life and life's processes. Biochemistry is sometime ...
... 2.0.1 Intro: What Is Biochemistry? Biochemistry is the study of the chemistry of, and relating to, biological organisms. It forms a bridge between biology and chemistry by studying how complex chemical reactions and chemical structures give rise to life and life's processes. Biochemistry is sometime ...
Identification of the Amino Terminus of Neuronal Ca2
... saline (as above plus 1.8 mM C aC l2 ) supplemented with 100 mg /ml penicillin, 100 I U/ml streptomycin (Life Technologies, Gaithersburg, MD), and 2.5 mM sodium pyruvate. Whole-cell recordings from oocytes were made in the two-electrode voltage-clamp configuration with a chloride-free solution conta ...
... saline (as above plus 1.8 mM C aC l2 ) supplemented with 100 mg /ml penicillin, 100 I U/ml streptomycin (Life Technologies, Gaithersburg, MD), and 2.5 mM sodium pyruvate. Whole-cell recordings from oocytes were made in the two-electrode voltage-clamp configuration with a chloride-free solution conta ...
Fatty acid synthesis in liver and adipose tissue
... to the high fat content of maternal milk (Ballard & Hanson, 1967). On weaning there is usually a change from a low- to a high-carbohydrate diet and this results in a marked increase in fatty acid synthesis and lipogenic enzyme activity in both liver and adipose tissue (Ballard & Hanson, 1967; Taylor ...
... to the high fat content of maternal milk (Ballard & Hanson, 1967). On weaning there is usually a change from a low- to a high-carbohydrate diet and this results in a marked increase in fatty acid synthesis and lipogenic enzyme activity in both liver and adipose tissue (Ballard & Hanson, 1967; Taylor ...
DEPARTMENT OF BIOCHEMISTRY UNIVERSITY OF KERALA
... undergraduate level and basic understanding of the theory and principle of the concerned subject. ...
... undergraduate level and basic understanding of the theory and principle of the concerned subject. ...
Haem biosynthesis and excretion of porphyrins
... oxidase, encoded by a gene on chromosome 1, catalyses the oxidation of protoporphyrinogen IX to protoporphyrin IX: six hydrogen atoms are removed (four from methylene bridges and two from pyrrole rings). Only oxidized molecules (porphyrins) are brightly coloured, whereas reduced porphyrins (porphyri ...
... oxidase, encoded by a gene on chromosome 1, catalyses the oxidation of protoporphyrinogen IX to protoporphyrin IX: six hydrogen atoms are removed (four from methylene bridges and two from pyrrole rings). Only oxidized molecules (porphyrins) are brightly coloured, whereas reduced porphyrins (porphyri ...
H - IS MU
... Fatty acids serve as an energy source for most of the cells (not for the nervous system and for red blood cells). The tissues gain fatty acids - either from lipoprotein particles after the triacylglycerols have been hydrolysed by lipoprotein lipase, - or as fatty acids mobilized by the action of hor ...
... Fatty acids serve as an energy source for most of the cells (not for the nervous system and for red blood cells). The tissues gain fatty acids - either from lipoprotein particles after the triacylglycerols have been hydrolysed by lipoprotein lipase, - or as fatty acids mobilized by the action of hor ...
Crystal structure of mouse coronavirus receptor
... within each coronavirus group, but differ markedly between different groups. S1 contains two independent domains, N-terminal domain (NTD) and C domain, that can both serve as viral receptorbinding domains (RBDs) (Table S1). C domain binds to APN or ACE2 in coronaviruses that use them as receptors (3 ...
... within each coronavirus group, but differ markedly between different groups. S1 contains two independent domains, N-terminal domain (NTD) and C domain, that can both serve as viral receptorbinding domains (RBDs) (Table S1). C domain binds to APN or ACE2 in coronaviruses that use them as receptors (3 ...
Cyclooxygenase mechanisms Lawrence J Marnett
... reconstitute the peroxidase activity by providing a distal base to facilitate proton transfer during Compound I formation (Figure 4) [21]. Generation of Compound I by reaction of ferric enzyme with hydroperoxide establishes a thermodynamically favorable sequence of reactions to initiate cyclooxygena ...
... reconstitute the peroxidase activity by providing a distal base to facilitate proton transfer during Compound I formation (Figure 4) [21]. Generation of Compound I by reaction of ferric enzyme with hydroperoxide establishes a thermodynamically favorable sequence of reactions to initiate cyclooxygena ...
Studies on the extra-mitochondrial CoA
... contains several ACSS and ACSM [1,3,4,7], and ACSL have been identified in the outer mitochondrial membrane [4,6]. Other ACSL have been found in the cytosol, smooth endoplasmatic reticulum, peroxisomes, mitochondria associated membranes (MAM) [4,6,8] and also in the plasma membrane. Recent experimen ...
... contains several ACSS and ACSM [1,3,4,7], and ACSL have been identified in the outer mitochondrial membrane [4,6]. Other ACSL have been found in the cytosol, smooth endoplasmatic reticulum, peroxisomes, mitochondria associated membranes (MAM) [4,6,8] and also in the plasma membrane. Recent experimen ...
Diabetes Mellitus Overview and Treatments
... cells called islets of Langerhans. The islets are endocrine tissue containing four types of cells. In order of abundance, they are: beta cells, which secrete insulin and amylin; alpha cells, which secrete glucagon; delta cells, which secrete somatostatin gamma cells, which secrete a polypeptide. ...
... cells called islets of Langerhans. The islets are endocrine tissue containing four types of cells. In order of abundance, they are: beta cells, which secrete insulin and amylin; alpha cells, which secrete glucagon; delta cells, which secrete somatostatin gamma cells, which secrete a polypeptide. ...
Diabetes
... cells called islets of Langerhans. The islets are endocrine tissue containing four types of cells. In order of abundance, they are: beta cells, which secrete insulin and amylin; alpha cells, which secrete glucagon; delta cells, which secrete somatostatin gamma cells, which secrete a polypeptide. ...
... cells called islets of Langerhans. The islets are endocrine tissue containing four types of cells. In order of abundance, they are: beta cells, which secrete insulin and amylin; alpha cells, which secrete glucagon; delta cells, which secrete somatostatin gamma cells, which secrete a polypeptide. ...
PDF - Biochemical Society Transactions
... enzyme-bound ally1 sulphoxide (1 l), which undergoes a 2,3-sigmatropic rearrangement to the electrophilic sulphenate ester (12). The latter is then captured by an enzymic nucleophile (12, arrows) resulting in irreversible inhibition of the enzyme. ...
... enzyme-bound ally1 sulphoxide (1 l), which undergoes a 2,3-sigmatropic rearrangement to the electrophilic sulphenate ester (12). The latter is then captured by an enzymic nucleophile (12, arrows) resulting in irreversible inhibition of the enzyme. ...
18. Metabolism of lipids 1
... Function: hydrolyses of TGs of chylomicrons and VLDL. Formed free fatty acids and glycerol pass into the cells Chylomicrons and VLDL which gave up TGs are called remnants of chylomicrons and remnants of VLDL Remnants are rich in cholesterol esters ...
... Function: hydrolyses of TGs of chylomicrons and VLDL. Formed free fatty acids and glycerol pass into the cells Chylomicrons and VLDL which gave up TGs are called remnants of chylomicrons and remnants of VLDL Remnants are rich in cholesterol esters ...
CoA
... 2. Malic enzyme and acetyl CoA carboxylase 3. For fatty acid synthase: a) substrates/key products; b) sources of NADPH; c) general mechanism 4. Relationship: regulation of carnitine-palmitoyl transferase-I and preventing oxidation of synthesized palmitoyl CoA ...
... 2. Malic enzyme and acetyl CoA carboxylase 3. For fatty acid synthase: a) substrates/key products; b) sources of NADPH; c) general mechanism 4. Relationship: regulation of carnitine-palmitoyl transferase-I and preventing oxidation of synthesized palmitoyl CoA ...
2016A Guerreiro Microbial Cell
... mM for S. cerevisiae [6-8]. Depending on the acid concentration, acetic acid may induce a PCD either with an apoptotic or a necrotic phenotype [6-8]. In S. cerevisiae, acetic acid - induced PCD with an apoptotic phenotype is known to be mediated by mitochondria, an organelle that fulfills crucial fu ...
... mM for S. cerevisiae [6-8]. Depending on the acid concentration, acetic acid may induce a PCD either with an apoptotic or a necrotic phenotype [6-8]. In S. cerevisiae, acetic acid - induced PCD with an apoptotic phenotype is known to be mediated by mitochondria, an organelle that fulfills crucial fu ...
Fatty Acid Oxid
... Glycerol, arising from hydrolysis of triacylglycerols, is converted to the Glycolysis intermediate dihydroxyacetone phosphate, by reactions catalyzed by: 1 Glycerol Kinase 2 Glycerol Phosphate Dehydrogenase. ...
... Glycerol, arising from hydrolysis of triacylglycerols, is converted to the Glycolysis intermediate dihydroxyacetone phosphate, by reactions catalyzed by: 1 Glycerol Kinase 2 Glycerol Phosphate Dehydrogenase. ...
Seminario Glúcidos 3 y lípidos 1. Comente los mecanismos de
... for added KC1 or other solute, previously shown to be necessary for the enzyme complex, can be demonstrated for the purified mitochondria only if these particles are first washed free of sucrose, which otherwise completely replaces added KCl, as previous work has shown (11). Schneider (14) reported ...
... for added KC1 or other solute, previously shown to be necessary for the enzyme complex, can be demonstrated for the purified mitochondria only if these particles are first washed free of sucrose, which otherwise completely replaces added KCl, as previous work has shown (11). Schneider (14) reported ...
Lipid signaling
Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. Lipid signaling is thought to be qualitatively different from other classical signaling paradigms (such as monoamine neurotransmission) because lipids can freely diffuse through membranes (see osmosis.) One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized ""on demand"" at their intended site of action. As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum.