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BL 616 Test 1 study guide. The test will probably have 20 multiple
BL 616 Test 1 study guide. The test will probably have 20 multiple

... Describe general features of eukaryotic cell Plasma membrane structure, including structures of phospholipids; where are carbohydrates Plasma membrane function including transport proteins, gated channels, active transport Describe structure/function of organelles and cytoskeleton Ch 11 Signal trans ...
C8605 - Datasheet - Sigma
C8605 - Datasheet - Sigma

... ceramides having a cis double bond have been produced. Dihydroceramides have a saturated sphingoid base. Phytoceramides occur in yeast and have a saturated sphingoid base with a third hydroxyl group. Ceramides are further classified based on the chain length and saturation of the fatty acid moiety. ...
Slide 1 - Ommbid.com
Slide 1 - Ommbid.com

... Hydrolysis of membrane-associated ceramide by acid ceramidase in the presence of saposins and bis(monoacylglycero)phosphate (BMP) in the acidic lysosomal compartment. According to a recent model on the topology of lysosomal digestion,47 ceramide hydrolysis takes place on intralysosomal vesicles. R = ...
Ceramides in human cells have important and divergent functions
Ceramides in human cells have important and divergent functions

... specific cellular functions. Sphingosine-1-phosphate (S1P) and ceramide-1-phosphate (C1P) are two important biological sphingolipids that have key roles in regulating many important physiological and pathological functions. These lipid species are much less studied than their ana-logs sphingosine an ...
Apoptosis
Apoptosis

... Pathways for the breakdown of GM1, globoside, and sphingomyelin to ceramide. A defect in the enzyme hydrolyzing a particular step is indicated by the partial breakdown product is noted. ...
Ref ID: 368
Ref ID: 368

... toxic forms. We have correlated drug resistance in neuroblastoma (NB) cell lines with mRNA overexpression of g-glutamylcysteine synthetase (g-GCS) and GSH-s-transferase µ (GSTµ), that code for glutathione synthesis and utilization enzymes. METHODS: We studied 20 NB cell lines containing 10 sensitive ...
< 1 ... 133 134 135 136 137

Lipid signaling



Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. Lipid signaling is thought to be qualitatively different from other classical signaling paradigms (such as monoamine neurotransmission) because lipids can freely diffuse through membranes (see osmosis.) One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized ""on demand"" at their intended site of action. As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum.
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