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... – Highly thermodynamically favorable, and regulated – Different enzymes in the different pathways – Differentially regulated to prevent a futile cycle ...
Respiration
Respiration

... transferred to carrier molecule NAD (nicotinamide adenine dinucleotide) to form reduced NAD (NADH) • Each NADH molecule can be used to transfer energy to other molecules during respiration • The end product of glycolysis, pyruvate (3C), still contains chemical potential energy ...
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Glyceroneogenesis



Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose. Usually glycerol 3-phosphate is generated from glucose by glycolysis, but when glucose concentration drops in the cytosol, it is generated by another pathway called glyceroneogenesis. Glyceroneogenesis uses pyruvate, alanine, glutamine or any substances from the TCA cycle as precursors for glycerol 3-phophate. Phosphoenolpyruvate carboxykinase (PEPC-K), which is an enzyme that catalyses the decarboxylation of oxaloacetate to phosphoenolpyruvate is the main regulator for this pathway. Glyceroneogenesis can be observed in adipose tissue and also liver. It is a significant biochemical pathway which regulates cytosolic lipid levels. Intense suppression of glyceroneogenesis may lead to metabolic disorder such as type 2 diabetes.
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