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Lecture 7 Citric acid cycle
Lecture 7 Citric acid cycle

... Stage 1: oxidation of fatty acids, glucose, and some amino acids yields acetylCoA. Stage 2: oxidation of acetyl groups in the citric acid cycle includes four steps in which electrons are abstracted. ...
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Overview of Carbohydrate Digestion and Metabolism

... 1. Control enzyme levels 2. Control of enzyme activity (activation or inhibition) 3. Compartamentalization Fatty acid oxidation occurs in mitochondrial matrix Fatty acid synthesis occurs in endoplasmic reticulum membrane exposed to the cytoplasm of the cell. ...
Overview of Carbohydrate Digestion and Metabolism
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... 1. Control enzyme levels 2. Control of enzyme activity (activation or inhibition) 3. Compartamentalization Fatty acid oxidation occurs in mitochondrial matrix Fatty acid synthesis occurs in endoplasmic reticulum membrane exposed to the cytoplasm of the cell. ...
Overview of Carbohydrate Digestion and Metabolism
Overview of Carbohydrate Digestion and Metabolism

... 1. Control enzyme levels 2. Control of enzyme activity (activation or inhibition) 3. Compartamentalization Fatty acid oxidation occurs in mitochondrial matrix Fatty acid synthesis occurs in endoplasmic reticulum membrane exposed to the cytoplasm of the cell. ...
Overview of Carbohydrate Digestion and Metabolism
Overview of Carbohydrate Digestion and Metabolism

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Biological importance of Uronic Acid Pathway
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Lecture 26
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Ch 26 Notes

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Glyceroneogenesis



Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose. Usually glycerol 3-phosphate is generated from glucose by glycolysis, but when glucose concentration drops in the cytosol, it is generated by another pathway called glyceroneogenesis. Glyceroneogenesis uses pyruvate, alanine, glutamine or any substances from the TCA cycle as precursors for glycerol 3-phophate. Phosphoenolpyruvate carboxykinase (PEPC-K), which is an enzyme that catalyses the decarboxylation of oxaloacetate to phosphoenolpyruvate is the main regulator for this pathway. Glyceroneogenesis can be observed in adipose tissue and also liver. It is a significant biochemical pathway which regulates cytosolic lipid levels. Intense suppression of glyceroneogenesis may lead to metabolic disorder such as type 2 diabetes.
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