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Introduction to Physiology: The Cell and General Physiology
Introduction to Physiology: The Cell and General Physiology

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... 12. Elaborate the role of NADPH in metabolic reactions. Explain the pathway in which it is obtained. 13. Explain urea cycle with its regulation. 14. Explain the role of RNA polymerase in prokaryotes. 15. What are the possible ways in which amino acids are oxidized? Mention any two reactions with str ...
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... of the individuals in a life-stage and gender group. The Recommended Dietary Allowance (RDA) is the daily intake level that meets the needs of most (97 to 98 percent) people in a life-stage and gender group. An Adequate Intake (AI) level is set when an RDA has yet to be established due to a lack of ...
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... glycolysis is shuttled to the mitochondria and further metabolized into carbon dioxide and water in a series of reactions. Although the aerobic pathway supplies ATP more slowly than does the anaerobic pathway, it releases more energy. ...
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Ketosis



Ketosis /kɨˈtoʊsɨs/ is a metabolic state where most of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis where blood glucose provides most of the energy. It is characterised by serum concentrations of ketone bodies over 0.5 millimolar, with low and stable levels of insulin and blood glucose. It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet, and deliberately induced ketosis serves as a medical intervention for intractable epilepsy. In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is sometimes referred to as the body's ""fat burning"" mode.
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