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4 phases of nuclear division (mitosis), directed by the cell’s DNA (PMAT) Prophase Metaphase—(Middle) Anaphase—(Apart) Telophase—(Two) Draw this! Prophase •Chromosomes coil and become visible •Centrioles (or poles) appear and begin to move to opposite end of the cell. Spindle fibers form between the poles. •Nuclear membrane disappears. Spindle Fibers Centrioles Metaphase •Chromosomes line up in the middle of the cell on the spindle fibers. Anaphase Chromosome copies divide Spindle fibers pull chromosomes to opposite poles Telophase •Chromosomes uncoil •Nuclear membrane reforms •2 new nuclei are formed •Spindle fibers disappear Stage 3: Cytokinesis •Cytoplasm and cell organelles divide evenly •Two new cells are formed •No cell wall: cell pinches in two •Cell wall: cell plate forms to separate the cells