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The Chemistry of Life Puzzle Paragraph Water Water molecules consist of two hydrogen atoms bonded to an oxygen atom. The hydrogen atoms have a slight ____________ charge and the oxygen atom has a slight ____________ charge. So, water molecules have two poles – a positive hydrogen pole and a negative oxygen pole. This feature of a molecule is called ____________. A bond can form between the positive pole in one water molecule and the negative pole of another. This is called a ____________ bond. In liquid water many of these bonds form, giving water properties that make it a very useful substance for living organisms. Properties of Water 1. ____________ Water molecules stick to each other because of the hydrogen bonds that form between them. Water is used as a transport medium in the xylem of plants. 2. ____________ Many different substances dissolve in water because of its polarity (sodium ions, glucose, enzymes). Water is the medium for metabolic reactions. 3. Thermal Properties: ____________ ____________ Water has a large heat capacity-large amounts of energy are need to raise its temperature, to break some of the hydrogen bonds. Blood, which is mainly composed of water, is used as a transport medium for heat. 4. Thermal Properties: ____________ ____________ The boiling point of water is 100*C because in order for it to change from a liquid to a gas all of the hydrogen bonds between the water molecules have to be broken. 5. Thermal Properties: ____________ ____________ ____________ Water can evaporate at temperatures below boiling point. Hydrogen bonds have to be broken to do this. The heat needed to break the bonds is taken from the liquid water, cooling it down. Water is a coolant (sweat, transpiration from plants) Elements in Living Organisms The four most common chemical elements of life are carbon, hydrogen, oxygen, and nitrogen. They are apart of all the main organic compounds in living organisms. 1. ____________ (S) Needed to make two of the twenty amino acids that proteins contain. 2. ____________ (Ca) Acts as a messenger, binding to calmodulin and other proteins that regulate processes inside cells, including transcription. Ex: minerals that strengthen teeth and bones 3. ____________ (P) Part of the phosphate groups in ATP and DNA molecules 4. ____________ (Fe) Needed to make cytochromes-proteins used for electron transport during aerobic cell respiration. Ex: makes hemoglobin Organic Compounds Compounds containing ____________ that are found in living organisms. (carbohydrates, lipids, and proteins) Inorganic Compounds All compounds that contain no carbon are ____________. There are a few carbon compounds that are inorganic even though they can be found in living organisms->carbon dioxide, carbonates, and hydrogen carbonates. Condensation Reaction In a condensation reaction two molecules are ____________ together for form a larger molecule. ____________ is also formed in the reaction. For example, two amino acids can be joined together to form a dipeptide by a condensation reaction. The new bond is called a ____________ Linkage. Peptide Linkage Condensation of two amino acids to form a ____________ and ____________. Polypeptide Further condensation reactions can link amino acids to either end of dipeptide, eventually forming a ____________ of many amino acids. Polysaccharide Condensation reactions are used to build up ____________ and ____________. The basic subunits of carbohydrates are monosaccharides. Two monosaccharides can be linked to form a disaccharide and more monosaccharides can be linked to a disaccharide to form a large molecule called a polysaccharide. Hydrolysis Reactions Using ____________ molecules, large molecules such as polypeptides, polysaccharides and triglycerides can be broken down into smaller molecules by hydrolysis reactions. Hydrolysis reactions are the ____________ of condensation reactions. Polypeptides + water -> dipeptides or amino acids Polysaccharides + water -> disaccharides or monosaccharides glycerides + water -> fatty acids + glycerol Monosaccharides (Ex of Carbohydrate) Glucose, galactose, fructose ____________ is carried by the blood to transport energy to cells throughout the body. ____________ is used to make fruits sweet-tasting, attracting animals to disperse seeds in the fruit. Disaccharides (Ex of Carbohydrate) Maltose, lactose, sucrose ____________ is the sugar in milk, that provides energy to young mammals until they are weaned. ____________ is carried by phloem to transport energy to cells throughout the plant. Polysaccharides Starch, glycogen, cellulose ____________ is used as a short-term energy store in liver and in muscles. ____________ is used to make strong fibers that are used to construct the plant cell wall. Function of Lipids ____________ storage- in the form of fat in humans and oil in plants ____________ insulation- a layer of fat under the skin reduces heat loss ____________ - lipids are less dense that water so help animals to float. Advantage of Lipids In Energy Storage Lipids used for long-term storage of ____________. Lipids contain more energy per gram than carbohydrates so stores of lipid are lighter than stores of carbohydrate that contain the same amount of energy. ____________ are insoluble in water, so they do not cause problems with osmosis in cells. Advantages of Carbohydrates In Energy Storage Carbohydrates are usually used for energy storage over ____________ periods. Carbohydrates are more easily digested than lipids so the energy stored by them can be released more rapidly. Carbohydrates are soluble in water so are easier to transport to an from the store. Nucleotides Basic units of ____________ molecule, composed of a sugar (deoxyribose), a phosphate, and one of 4 DNA bases (Adenine, cytosine, guanine, and thymine). Enzymes Enzymes are globular proteins which act as catalysts of chemical reactions. Without enzymes to ____________ them, many chemical processes happen at a very slow rate in living organisms. By making some enzymes and not others, cells can control what chemical reactions happen in their cytoplasm. Denaturation Denaturation is changing the ____________ of an enzyme (or other protein) so that it can no longer carry out is function. Usually Permanent. Substrates In chemical reactions, one or more reactants are converted into one or more products. In reactions catalyzed by enzymes the reactants are called ____________. Enzyme-Substrate Specificity Most enzymes are ____________ - they catalyze very few different reactions. They therefore only have a very small number of possible substrates. This is called enzymesubstrate specificity Active Site An active site is a region on the surface of an enzyme to which ____________ bind and which catalyze a chemical reaction involving the substrates. Factors Affecting Enzyme Activity Temperature, pH, inhibitors and substrate concentration all affect the ____________ at which enzymes catalyze chemical reactions. Effect of Temperature Enzyme activity ____________ as temperature increases, often doubling with every 10*C rise. This is because collisions between substrate and active site happen more frequently at higher temperatures due to faster molecular motion. At high temperatures enzymes are ____________ and stop working. This is because heat vibrations inside enzymes which break bonds needed to maintain the structure of the enzyme. Effect of pH Optimum pH at which enzyme activity is fastest (pH of 7 is optimum for most enzymes). As pH increases or decreases from the ____________, enzyme activity is reduced. Both acids and alkalis can denature enzymes. Effect of Substrate Concentration At low substrate concentrations, enzyme activity increases steeply as substrate concentration increases. This is because random collisions between substrate and active site happen more frequently with ____________ substrate concentrations. At high substrate concentrations most of the active sites are occupied, so raising the substrate concentration has ____________ effect on enzyme activity. Lactose-free Milk Lactose is the sugar that is naturally present in milk. It can be converted into glucose and galactose by the enzyme ____________. lactose->(lactase)-> glucose + galactose