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Anatomy and Physiology Notes NCSCOS – 4.02, 4.03, 4.04 1. Integumentary System - Structure • Skin – composed of 2 major layers – dermis and epidermis • Epidermis – outer layer, 2 parts interior and exterior – Exterior – 25-30 layers dead cells, shed continously, contains keratin – Interior – living cells that replace exterior cells, contains melanin (pigment) Dermis – inner, thicker portion – holds blood vessels, nerves, sweat and oil glands, hair follicles • Regulation of body T – blood vessels expand and constrict, sweat • Sense organ • Produces essential vitamins (D) • Protective layer 2. Muscular System • Smooth – found in walls of intestine, blood vessels, internal organs. Peristalsis, involuntary control • Cardiac – heart, conduct electricity, involuntary control • Skeletal – striated, attach to and move your bones, voluntary control 3. Skeletal System • 206 bones in skeleton – divided into two main parts • Axial – bones of skull, vertebral column, ribs, sternum • Appendicular – bones of arms and legs • Bones connect at joints – movable and immovable • • • • • • • • • • • • • • • • • Held with ligaments (bone to bone) and tendons (muscle to bone) 4 types of joints Ball and socket – allow for rotational movement Hips and shoulders Pivot – bones twist around each other forearm Hinge – back and forth movement knees Gliding – bones slide past each other Wrists Framework Protection Efficient movement Produces blood cells in red marrow and fat in yellow marrow Stores minerals – ex. calcium 4. Circulatory System - Function • Pumps blood to all parts of body • Blood – – Transports oxygen and nutrients – Removes waste – Transports immune system cells • Composed of heart and blood vessels • Vessels include – – Arteries – carries blood away from the heart, branches into arterioles and capillaries – Veins carry blood towards the heart, branch into venules • Mammalian heart has 4 chambers • Upper two are atria and lower two are ventricles (pumping chambers) • RA receives oxygen poor blood from body. • RA pumps blood to RV • RV pumps blood to lungs through pulmonary artery. Blood becomes oxygen rich • Oxygen rich blood sent to LA through the pulmonary vein • LA pumps oxygen rich blood to LV • LV pumps oxygen rich blood to body 6. Digestive System - Function • • • • • • • • • • Breaking down and processing food by absorbing nutrients and eliminating waste Can be physical or chemical Begins in mouth – physical digestion by chewing, chemical digestion by salivary amylase (starches) Food is swallowed and goes down esophagus, peristalsis moves the food into the stomach Stomach muscles continue physical digestion Chemical digestion by stomach acid 2-4hrs. – food enters small intestine In small intestine muscles continue physical Numerous compounds for chemical Pancreas secretes enzymes that break down carbs, proteins, and nucleic acids • Liver produces bile • Bile is stored in gall bladder and secreted into small intestine to help break down fats • Food is now nutrients, waste, and water • Nutrients are absorbed by the small intestine through villi and enter the blood stream • Water and waste go to lg. intestine • Water is absorbed and solid waste is excreted 7. Respiratory System • Primary function is gas exchange • Take in oxygen and release carbon dioxide • Primary organ is lungs 8. Urinary System - Function Filters blood, reabsorbing nutrients and eliminating wastes • • • Kidneys are made of cells called nephrons Nephrons filter blood and remove wastes (mainly dilute ammonia = urea), leaving nutrients in blood Wastes are sent down ureters to the urinary bladder, leave body through urethra 9. Nervous System • Function – transmit neural impulses through body • Structure – made of neurons (nerve cells) • Neuron – – Cell body – Dendrites –receive impulses – Axons – send impulses • Divided into central nervous system (CNS) and peripheral nervous system (PNS) • Three types of neurons – Sensory – carry impulse from body to CNS – Interneurons – in CNS, process impulse and prepare response – Motor – carry response from CNS to origin of impulse 10. Endocrine System • Endocrine glands that secrete hormones (chemical messengers) • Found throughout the body • Hypothalamus and pituitary glands control the activity of many others • Specific for specific receptors • Function in positive feedback and negative feedback (thermostatic control) • Ex. of negative feedback – insulin and glucagon controlling blood sugar (glucose) levels • Adrenal glands – fight or flight • Thyroid glands – regulate growth, development, and metabolism 11. Immune System • All of the defenses against pathogens (any disease causing agent) • Different lines of defense • innate – nonspecific, same response to a variety of pathogens • Acquired (specific) – specific responses to specific pathogens • • Innate: Skin, mucous membranes, secretions • • • • • Phagocytic cells – white blood cells that engulf pathogens Antimicrobial proteins Inflammatory response – fever and inflammation increases blood flow to an area, increases WBC in the area Natural killer cells – destroy tumors Interferon – distress signal sent out by cells infected by viruses Acquired: • Specific immunity operate on “self vs. nonself” principle • Lymphocytes (special white blood cells) function in specific immunity – B cells – make antibodies, protect against extracellular pathogens – bacteria, worms, fungus, etc. – T cells – protect against intracellular pathogens (viruses, cancer) by making cytotoxic T cells – Helper T – coordinate efforts of B and T cells • B and T cells both make memory cells that protect against future attack by the SAME pathogen