Download Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation Brochure

Brochure
More information from http://www.researchandmarkets.com/reports/2237721/
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation
Description:
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific
researchers with a deep understanding of the current research in this field and the implications for
translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune
rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians
who need a broad view of the deeply complex processes involved. It then moves on to discuss the
immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL)
effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent
successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance
the prospects for the future.
Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a
genetically similar but not identical donor. This procedure is commonly performed for people with diseases
of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As
such, experimental practice is reserved for preclinical animal models including the mouse and dog.
These animal models have been essential in developing transplant protocols, including preclinical testing of
conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the
immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant
species differences between humans and animal models that must be considered when relating animal
model studies to clinical allogeneic HSCT scenarios.
- Brings together perspectives leading laboratories and clinical research groups to highlight advances from
bench to the bedside
- Guides readers through the caveats that must be considered when drawing conclusions from studies with
animal models before correlating to clinical allogeneic HSCT scenarios
- Categorizes the published advances in various aspects of immune biology of allegeneic HSCT to illustrate
opportunities for clinical applications
Contents:
Overview of the immune biology of HSCT
The HLA system
Minor Histocompatibility antigens
In vivo imaging of GVHD and GVL
Immune rejection
The basis of immune deficiency
Tumor associated antigens
Impact of the conditioning regimen
Dendritic cells in GVHD
Costimulatory molecules in GVHD and GVL
Conventional T cells in GvHD and GVL
Regulatory T cells in GVHD and GVL
Th17 in GVHD and GVL
B cells in GVHD and GVL
Cytokines in GVHD and GL
Chemokines in GVHD and GL
Intracellular sensors
Proteomics in GVHD and GVL
The endothelium in GVHD and GVL
Immune Biology of the future
Ordering:
Order Online - http://www.researchandmarkets.com/reports/2237721/
Order by Fax - using the form below
Order by Post - print the order form below and send to
Research and Markets,
Guinness Centre,
Taylors Lane,
Dublin 8,
Ireland.
Page 1 of 2
Fax Order Form
To place an order via fax simply print this form, fill in the information below and fax the completed form to 646-607-1907 (from
USA) or +353-1-481-1716 (from Rest of World). If you have any questions please visit
http://www.researchandmarkets.com/contact/
Order Information
Please verify that the product information is correct.
Product Name:
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation
Web Address:
http://www.researchandmarkets.com/reports/2237721/
Office Code:
SCHL3FA7
Product Format
Please select the product format and quantity you require:
Quantity
Hard Copy (Hard
Back):
USD 179 + USD 29 Shipping/Handling
* Shipping/Handling is only charged once per order.
Contact Information
Please enter all the information below in BLOCK CAPITALS
Title:
First Name:
Mr
Mrs
Dr
Miss
Last Name:
Email Address: *
Job Title:
Organisation:
Address:
City:
Postal / Zip Code:
Country:
Phone Number:
Fax Number:
* Please refrain from using free email accounts when ordering (e.g. Yahoo, Hotmail, AOL)
Ms
Prof
Page 2 of 2
Payment Information
Please indicate the payment method you would like to use by selecting the appropriate box.
Pay by credit card:
You will receive an email with a link to a secure webpage to enter your
credit card details.
Pay by check:
Please post the check, accompanied by this form, to:
Research and Markets,
Guinness Center,
Taylors Lane,
Dublin 8,
Ireland.
Pay by wire transfer:
Please transfer funds to:
Account number
833 130 83
Sort code
98-53-30
Swift code
ULSBIE2D
IBAN number
IE78ULSB98533083313083
Bank Address
Ulster Bank,
27-35 Main Street,
Blackrock,
Co. Dublin,
Ireland.
If you have a Marketing Code please enter it below:
Marketing Code:
Please note that by ordering from Research and Markets you are agreeing to our Terms and Conditions at
http://www.researchandmarkets.com/info/terms.asp
Please fax this form to:
(646) 607-1907 or (646) 964-6609 - From USA
+353-1-481-1716 or +353-1-653-1571 - From Rest of World