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Bubonic Plague The Black Death By: Zach & Amber Purpose To simulate the impact of an epidemic of the plague on a large city in the Middle Ages. The Assumptions • recovered humans would become susceptible once more. • rat couldn’t affect humans. • fleas couldn’t infect rats. • rats would infect each other. History • deadly bacteria that struck 14th century China and Europe . • affected rodents • fleas carried it to humans. • extremely contagious, spread quickly • Yersinia Pestis. Historical Progression of Bubonic Plague Symptoms • • • • • • • • • shivering vomiting headache giddiness intolerance to light pain in back and limbs white coating on tongue Internal bleeding lymph nodes swelled (“buboes”) Treatmeant & Prevention • The Bubonic plague is only treatable if it is caught early on. • Streptomycin and Tetracyclines is the preferred drug • Penicillin is useless on the plague. • Better sanitary conditions and precautions. Vaccine • Lasts about 6 months. • Unavailable in the US. • Treatment shortly after exposure can reduce overall plague mortality. • Preferred for children 8 or under. • rat pop should be controlled using rodenticide. • isolating all infected human being so that others would not be affected. • wearing excrement • effective insecticides should be used. Human Model To tal Hu man popu lati on Recovered Hu mans Becomi ng s uscepta ble In fected flea s Norma l hu man death rate Huma n bi rth ra te Norma l de aths of infe cte d Huma ns ~ Huma n bi rths Huma n in fection rate In fected Hu mans Recovery of huma ns Sus cep tibl e Huma ns In fection of huma ns Norma l hu man deaths Deaths o f recovered hum ans Death fro m in fection Norma l hu man death rate Norma l hu man death rate Death rate of infection of h uman s Rat Model Li ve births p er fe male rat Fe male rats In fected death rate of rats Rat birth s In fected rats In fection of rats Sus cep tibl e rats Norma l de aths of rats Deaths from i nfectio n of rats In fection rate Ordin ary dea ths of ra ts Norma l de ath rate of ra ts Norma l de ath rate of ra ts To tal rate popu lati on Flea Model To tal flea pop ulation La rva l stage flea s Sus cep tibl e fl eas In fection of flea s In fected flea s Death of fle as from i nfectio n Fl ea b irths Fl ea g rowth Norma l Deaths o f fl eas Death rate of fle as from i nfectio n Odin ary fle a de aths ~ Fl ea b irth rate Fl ea i nfectio n rate Fe male fle as In fected rats Norma l fl ea d eath rate Norma l fl ea d eath rate Results Results Results References • http://ponderosapine.uoregon.edu/student/Janis/prevention.html • model and case study narrative by: Robert R. Gotwals, Jr. Consulting support by: Dr.. Ken Gage, Division of Vector-Borne Infectious Disease, Center for Disease Control, Boulder Colorado. (Case Study/from Book) • http://www.byu.edu/ipt/projects/middleages/LifeTimes /Plague.html The End