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Ch. 12 The Nervous System and Nervous Tissue Objectives • Understand how the nervous system is divided and the types of cells that are found in nervous tissue • Know the anatomy of a neuron and the structural and functional types of neurons • Understand what occurs at the synapse The Nervous System • Maintains internal coordination – Sensory information – Processing – Response • Two major subdivisions – Central (CNS) • Brain and spinal cord – Peripheral (PNS) • Nerves and ganglia Divisions of Nervous System legacy.owensboro.kctcs.edu Divisions of Nervous System • CNS – brain and spinal cord • PNS – Cranial nerves – Spinal nerves – Sensory division • Sensory information form environment to CNS – Motor division • Somatic – Impulses to skeletal muscle • Autonomic – Impulses to cardiac and smooth muscle, glands » Sympathetic » parasympathetic Neurons • Communication cells of the nervous system • Properties that allow communication – Excitability – Conductivity – Secretion • Three functional classes – Afferent (sensory) neurons – Interneurons (association neurons) – Efferent (motor) neurons Neuron Structure • Soma – control center – Chromatophilic (Nissl) bodies – Neurofibrils • Dendrites – Receptive sites – Conduct towards • Axon Hillock • Axon – Impulse generators – Conduct away mindcreators.com Synapse • Site of neuronal communication • Two types – Axodendritic – Axosomatic • Synaptic cleft – neurotransmitters catalog.nucleusinc.com Structural Classification science.howstuffworks.com Neuroglial Cells • Four types of glial cells – Astrocytes • Synapse formation – Brain derived trophic factor • Nourish • Regulation of neurotransmitters • K+ regulation – Oligodendrocytes • myelination – Microglia • Immune protection • Macrophages – Ependymal cells • Internal lining of CNS • Production of CSF • Two types of glial cells found only in PNS – Schwann cells • Myelination – Satellite cells • Provide electrical insulation around soma • Chemical regulation Myelination nature.com faculty.stcc.edu Nerves • Nerve – Collection of nerve fibers in the PNS • Nerve composed of multiple axons • Epineurium • Perineurium – Fascicles • endoneurium web.uaccb.edu Grey and White Matter of CNS • Grey matter – cell bodies, dendrites, unmyelinated axons, neuroglia • White matter – Myelinated axons histology.leeds.ac.uk Reflex Arcs • Reflex – Rapid, autonomic motor responses to stimuli – Somatic or visceral • Monosynaptic – Direct connection between afferent and efferent neurons • Polysynaptic – One or more interneurons involved Spinal Reflexes Neuronal Circuits • Diverging circuits – Signal is passed to many pathways • Converging circuits – Various signals influence one neuron • Reverberating circuit – One neuron in a series sends feedback to a previous neuron in the circuit • Serial and Parallel processing Disorders of the Nervous System • Multiple Sclerosis – Autoimmune attack of myelin on CNS axons • Neuronal Regeneration – Possible to regenerate axons of PNS – Regeneration tubes