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Transcript
Endocrine System Anatomy of the Endocrine System Which organs did you not expect to be included as endocrine organs? List some of the general functions of hormones. Pituitary Gland (See similar figure in your packet) Why is this gland considered an important link between the nervous and endocrine systems? What is a tropic hormone? Hypothalamic Control of Endocrine Organs How do these regulatory hormones get to the adenohypophysis? Sympathetic or Parasympathetic? Hypothalamic Regulation of Endocrine Glands HYPOTHALAMUS (neu rons) Body T emp. Blood nu trien ts Water balanc e Blood p ressure Emotion al state Etc. releasing / inh ibit ing hormon es * NEUROHYPOPHYSIS (neu ron axons ) in HYPOPHYSEAL PORTAL VEINS ADENOHYPOPHYSIS (glandula r portion ) Condi tion = neg ativ e feedback * = neu ron fir ing This figure is also found in your course packet. Hypothalamic Regulation of Blood Glucose Between Meals (A negative feedback mechanism via the hypothalamus) Normal Blood Glucose (80-110mg/dl) BS BS LIVER HYPOTHALAMUS (gluconeogenesis) Cortisol CRH ADRENAL CORTEX ANTERIOR PITUITARY ACTH Neurosecretory Cells in the Hypothalamus Name at least 3 hormones involved in regulating water balance. The neurohypophysis develops from: a) Telencephalon b) Diencephalon c) Mesencephalon d) Rhombencephalon Hypothalamic Regulation of Water Balance Normal Water Balance Water Voluntary water intake KIDNEY ECF, ICF (Dehydration) HYPOTHALAMUS (Osmoreceptors) Antidiuretic Hormone (Vasopressin) NEUROHYPOPHYSIS (Posterior pituitary) This figure is also found in your course packet. Thyroid Gland Which mineral is essential in the production of hormones from thyroid follicles? What is thyroglobulin? Which endocrine cells produce thyrocalcitonin? Parathyroid Glands Describe the complete homeostatic mechanism involving parathyroid hormone and thyrocalcitonin. Why is calcium regulation so important to body function? (Name at least 3 functions of Ca+2.) Cells of the adrenal cortex are derived from mesoderm. Where are the cells of the adrenal medulla from? Adrenal Glands How is hormone release from the adrenal cortex controlled? … from the adrenal medulla? Renin-Angiotensin-Aldosterone System in the Regulation of Water Balance Normal Blood Volume/ Normal BP Na+ , Water K+ , Na+ KIDNEY BP KIDNEY Aldosterone (plasma) Renin (plasma) ADRENAL CORTEX (Zona Glomerulosa) ACE Angiotensin II Angiotensin I Vasoconstriction ( BP, and venous return) Stimulates ADH release Thirst This Angiotensinogen figure is also found in your course packet. Pancreas The pancreas also has an exocrine function. Where are these products released? Describe the overlapping homeostatic mechanisms involving insulin and glucagon. Glucose Homeostasis Reproductive Glands Ovarian hormones include estrogens, progesterone, relaxin and inhibin. The testes produce testosterone and inhibin. (Table 23.8) The placenta also produces estrogen and progesterone. Why? Other Endocrine Tissues and Their Secretions • Pineal gland: Melatonin – What is the significance of its location near the thalamus? – Why is it significant that this gland is innervated by sympathetic nerves? • Thymus gland: Thymosin – What effect might a reduction in thymosin production have on one’s ability to defend against disease? • Adipocytes: Leptin – How is obesity hypothesized to be related to early puberty? … Continued • Heart: Atrial Natriuretic Peptide (ANP) – What does the name of this hormone tell you about its action? • Stomach: Gastrin – Briefly describe the positive feedback mechanism involving Gastrin • Kidneys: Erythropoietin – What is the target tissue for this hormone?