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DEPRESSION Antonija Jukić Mentor: A. Žmegač Horvat The words above belong to author William Styron, and they describe his first episode of major depression This experience belongs to millions Definition of MAJOR DEPRESSIVE DISORDER Mental disorder characterized by an allencompassing low mood accompanied by low self-esteem, and loss of interest or pleasure in normally enjoyable activities Depressed weeks mood persists for at least two Subtypes Melancholic Atypical depression depression Catatonic depression Postpartum Seasonal depression affective depression Symptoms and signs Feelings of helplessness and hopelessness Loss of interest in daily activities Appetite or weight changes Sleep changes Irritability or restlessness Loss of energy Self-loathing Concentration problems Unexplained aches and pains Depression and suicide!!! 3.4% of people with major depression commit suicide 60% of people who commit suicide have depression or another mood disorder Causes and risk factors for depression Loneliness Lack of social support Recent stressful life experiences Family history of depression Marital or relationship problems Financial strain Early childhood trauma or abuse Alcohol or drug abuse Unemployment or underemployment Health problems or chronic pain Biological theories Dysregulation of monoamine chemicals serotonin, norepinephrine and dopamine in the brain Most antidepressants increase the levels of one or more of the monoamines Diagnosis Patient's self-reported experiences Behavior reported by relatives or friends Mental status exam No laboratory test for major depression Differential diagnoses Dysthymia Adjustment disorder with depressed mood Bipolar disorder Management Antidepressant medication (MAOIs, TCAs, SSRIs) – delayed onset of action (2-6 weeks)!!! Psychotherapy or counselling Hospitalization Electroconvulsive therapy (ECT) Prevention - Lifestyle changes! Cultivating supportive relationships Getting regular exercise and sleep Eating a healthy, mood-boosting diet Managing stress Practicing relaxation techniques Challenging negative thought patterns SMILE References www.wikipedia.org www.helpguide.org