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Chapter 2: Structural Organization of the body Body Cavities, Regions and Quadrants; Body Planes, Positions, and Directions Ms. Nina Starnes The Body’s levels of Organization The Cell The cell is the fundamental unit and building blocks of all living things. Cells are in all parts of the body including, every tissue and organ. The human body is composed of trillions of cells, That provide structure for the body, take in nutrients from food, convert nutrients into energy, and carry out specialized functions. Cells also contain the body’s hereditary material and can make copies of themselves. Parts and functions of the Cell The cell Membrane: surrounds and protects the cell. It is semi-permeable, which means it is selective about what it allows to pass in and out of it. The term osmosis describes the movement of a solvent through a semi- permeable membrane from a less concentrated solution to a more concentrated one; as in how cells allow small molecules to enter and exit the cell. Parts and functions of the Cell cont… The nucleus: Is the brain of the cell. The nucleus serves as the cell’s command center, sending directions to the cell to grow, mature, divide, or die. It also houses DNA, which is the cell’s hereditary material. The nucleus is surrounded by a membrane called the nuclear envelope/membrane, which protects the DNA and separates the nucleus from the rest of the cell. Parts and functions of the Cell cont… Chromosomes: are rod like structures within the nucleus. All human body cells contain 23 pairs of chromosomes (except for sex cells; the ovum and sperm). Each sperm and egg cell has only 23 un paired chromosomes. After the sperm and egg cells unite to form the embryo, each cell of the embryo, then has 46 chromosomes (23 pairs). Chromosomes also contain regions/sections called genes. There are several thousand genes, in an orderly sequence, on each chromosome. Each gene is composed of a chemical called DNA (deoxyribonucleic acid). DNA regulates the activities of the cell. The DNA is like a series of recipes in code. When the code is carried outside the nucleus, it directs the activities of the cell, such as cell reproduction, and the manufacture of proteins. The Human Cell Karyotype: Chromosomes within the nucleus can be analyzed in terms of their size, arrangement and number, by performing a karyotype. This is used to determine whether the chromosomes are normal in number and structure; an example is an amniocentesis What do you see that’s different? Is this a girl or a boy? Parts and functions the Cell cont… Cytoplasm: is a gel-like material outside the nucleus and enclosed by the cell membrane; it contains water and nutrients for the cell. Mitochondria: (the power house of the cell) small rod shaped bodies that produce and release energy to the cell by burning food in the presence of oxygen. This is called Catabolism; in which complex foods (sugar and fats) are broken down into smaller substances that the cell can use, and energy is released to do the work of the cell. What is this energy called? Parts and functions of the Cell cont… Endoplasmic Reticulum: a network of canals that serve as a cellular tunnel system in which proteins are manufactured for use in the cell. Ribosomes are located on the endoplasmic reticulum, and is where the proteins are made for the cell. The process of building up complex materials, such as the building of large proteins; is called Anabolism. What are the building blocks of proteins? Parts and functions of the Cell cont… Metabolism: is the combination of two processes, anabolism and catabolism. It is the total of the chemical processes occurring in a cell (heat lost and produced). If a person has a “fast metabolism” then foods such as sugars and fats are used up very quickly and energy is released. If a person has “slow metabolism” foods are thought to be burned very slowly and fat accumulates in the cells. Parts and functions of the Cell cont… Lysosomes: (suicide bag of the cell) are chemical used to digest waste. Capable of digesting nonessential parts of the cell to avoid cell death. Golgi Apparatus (body): (the UPS of the cell) are used for the packaging and secreting of energy in and out of the cell. Cell Differences Are all cells the same? No. Cells are different or specialized throughout the body to carry out their individual functions. For example a Muscle cell is long and slender and contains fibers that aid in contracting and releasing. A Nerve cell is elongated and has extensions aiding in carrying impulses, and Epithelial cells are flat and square to provide protection for the underlying tissues. A Fat cell contains large empty spaces used for fat storage. There are many different types of cells in the body, that have different appearances and functions; the above mentioned are just a few. Tissues: Body Tissues Are cells grouped together in the body that form tissues. They are a collection of similar cells that group together to perform a specialized function. There are 4 primary tissue types in the human body: Epithelial tissue, connective tissue, Muscle tissue and Nerve tissue. 1. Epithelial Tissue - The cells of epithelial tissue pack tightly together and form continuous sheets that serve as linings in different parts of the body. Epithelial tissue serve as membranes lining organs and helping to keep the body's organs separate, in place and protected. Some examples of epithelial tissue are the outer layer of the skin, the inside of the mouth and stomach, and the tissue surrounding the body's organs. Body Tissues cont… 2. Connective Tissue - There are many types of connective 3. Muscle Tissue - Muscle tissue is a specialized tissue that 4. Nerve Tissue - Nerve tissue contains two types of cells: tissue in the body. Generally speaking, connective tissue adds support and structure to the body. Most types of connective tissue contain fibrous strands of the protein collagen that add strength to connective tissue. Some examples of connective tissue include the inner layers of skin, tendons, ligaments, cartilage, bone and fat tissue. In addition to these more recognizable forms of connective tissue, blood is also considered a form of connective tissue. can contract. Muscle tissue contains the specialized proteins actin and myosin that slide past one another and allow movement. Examples of muscle tissue are contained in the muscles throughout your body. neurons and glial cells. Nerve tissue has the ability to generate and conduct electrical signals in the body. These electrical messages are managed by nerve tissue in the brain and transmitted down the spinal cord to the body Organs Organs: are the next level of organization in the body. An organ is a structure that contains at least two different types of tissues functioning together for a common purpose. There are many different organs in the body: the liver, kidneys, heart, even your skin is an organ. In fact, the skin is the largest organ in the human body and provides us with an excellent example for explanation purposes. The skin is composed of three layers: the epidermis, dermis and subcutaneous layer. The Epidermis is the outermost layer of skin. It consists of epithelial tissue in which the cells are tightly packed together providing a barrier between the inside of the body and the outside world. Below the epidermis lies a layer of connective tissue called the Dermis. In addition to providing support for the skin, the dermis has many other purposes. The dermis contains blood vessels that nourish skin cells. It contains nerve tissue that provides feeling in the skin. And it contains muscle tissue that is responsible for giving you 'goose-bumps' when you get cold or frightened. The Subcutaneous layer is beneath the dermis and consists mainly of a type of connective tissue called adipose tissue. Adipose tissue is more commonly known as fat and it helps cushion the skin and provide protection from cold temperatures Organ Systems: Organ Systems Organ Systems: Organ systems Organ Systems: Organ Systems: Body Cavities There are two main cavities within the body, the ventral and the dorsal cavities. Dorsal cavity: The dorsal body cavity is at the back of the body . It can be further divided into the upper and lower portions, the cranial cavity and the spinal canal. Cranial cavity Upper portion. Bounded by the skull. Brain and meninges. Vertebral canal Lower portion. Bounded by the vertebral column, intervertebral discs and surrounding ligaments. Spinal cord, spinal nerve roots. Ventral cavity: Is divided into three cavities, the thoracic cavity, abdominal cavity and pelvic cavity. The thoracic and abdominal cavities are divided by the diaphragm and the abdominal and pelvic cavities are continuous with each other. Thoracic cavity Large cavity above the diaphragm. It is bound laterally by the ribs and the diaphragm inferiorly. Encloses the Heart, lungs, trachea, esophagus, large blood vessels and nerves. Abdominal cavity Large cavity below the diaphragm. It is bound superiorly by the diaphragm, laterally by the body wall, and inferiorly by the pelvic cavity. Gastrointestinal tract, spleen, kidneys and adrenal glands. Pelvic cavity Small cavity below the brim of the pelvis. It is bounded superiorly by the abdominal cavity, posteriorly by the sacrum, and laterally by the pelvis, Urinary bladder, genitals, sigmoid colon and rectum. Quadrants of the Abdomen The abdomen can be divided by 2 lines into 4 Quadrants or by 4 lines into 9 Regions. The two lines that divide the abdomen into quadrants form a cross, the center of which is positioned over the umbilicus (belly button). These quadrants are often used to indicate the location of pain. Right upper quadrant Liver, gallbladder, right kidney, duodenum, a portion of the ascending and transverse colons and the small intestine. Left upper quadrant Stomach, spleen, left kidney, pancreas, a portion of the descending and transverse colons and the small intestine. Right lower quadrant Appendix, cecum, a potion of the ascending colon and the small intestine. Left lower quadrant A portion of the descending and transverse colons and the small intestine. REGIONS OF THE ABDOMEN Right hypochondriac region Left hypochondriac region Epigastric region Right lateral region Left lateral region Umbilical region Right inguinal region Hypogastric (pubic) region Left inguinal region Vertebral column. 7 Cervical vertebrae (C1-C7) neck region 12 Thoracic vertebrae (T1-T12) chest region 5 Lumbar vertebra (L1-L5)waist region 5 (fused) Sacrum (S1-S5) 4 (fused) Coccygeal vertebrae (tail bone) Anatomical Directions Direction is used, when the body is in the anatomical position to explain the location of a structure relative to the structures surrounding it. Anterior (or ventral) Towards the front of the body (in front of). The sternum lies anterior to the heart. Posterior (or dorsal) Towards the back of the body (behind). The heart lies posterior the sternum. Superior (or cranial) Above (on top of). The heart lies superior to the diaphragm. Inferior (or caudal) Below (underneath). The diaphragm lies inferior to the heart. Lateral Away from the mid line of the body (towards the sides). The lungs lie lateral to the heart. Medial Towards the mid line of the body (towards the middle). The heart lies medial to the lungs. Deep Away from the body surface (towards the inner body). Ex. A stab wound deep into the abdomen Superficial Towards the external surface of the body. The sternum is superficial to the heart. Proximal Nearer to the trunk of the body. The shoulder is proximal to the elbow. Supine Lying on the back. Face UP Prone Lying on the belly. On face Distal far from the point of attachment to the trunk, or from the beginning of the structure. Proximal Near the point of attachment to the trunk, or near the beginning of the structure. Anatomical Planes transverse (Cross-sectional plane ) This plane cuts the body horizontally, into superior (upper) and inferior (lower) portions. Frontal (Coronal plane) This plane cuts the body vertically, into anterior (front) and posterior (back) portions. Sagittal (lateral) This plane cuts the body vertically, into left and right portions. Thank you for your attention!