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The Nervous System BY LYDIA CHANG, LAUREN LEE, AND DIANA ZHENG Evolution of the Nervous System Porifera: no nervous system Cnidaria: nerve net all throughout body—can react to stimuli from all sides Platyhelminthes: cephalization; ganglia, eyespots, two main ventral nerve cords Rhynchocoela: dorsal nerve cord, two lateral nerve cords Nematoda: ring of nervous tissue around pharynx attached to dorsal and ventral nerve cords Annelida: pair of brain-like cerebral ganglia and subpharyngeal ganglion Mollusca: ranges from simple nervous system to relatively complex systems that rival those of mammals Arthropoda: cerebral ganglion (brain!); sense organs concentrated on head Echinodermata: decentralized nervous; no brain but have ganglia along radial nerves in some species; sensory neurons within podia Evolution of the Nervous System Vertebrates: very centralized and cephalized; well-developed sensory organs; dorsal, hollow nerve cord (spinal cord) Lampreys and hagfishes: no myelin sheath Fish: enlarged cerebellum Amphibians: growing importance of forebrain, but midbrain still important Reptiles/Birds: many connections between thalamus and hemispheres Birds: larger cerebellum Mammals: brain completely dominated by cerebral hemispheres; large surface area; controlled mainly by cortex; large thalamus The Human Nervous System Brain: about 2% human body mass Neocortex: outer layer of brain Human cerebral cortex (aka pallium): flat sheets of cells in six layers Frontal lobe: reasoning, speech, motor cortex Parietal lobe: speech, taste, reading, somatosensory cortex Temporal lobe: hearing, smell, auditory Occipital lobe: sight Cerebellum: ballistic movements, balance, coordination, helps in learning and remembering motor skills From “Vertebrate Nervous System” The Brain, cont’d Diencephalon: major integrating centers information, act as relay stations for info flow Thalamus: main relay center for sensory information Hypothalamus: maintains homeostasis Brain stem: includes the pons, medulla oblongata transfers info between peripheral and central nervous systems helps coordinate large-scale body movements (e.g. running) nerve crossing: right side of brain controls left side of body and vice versa Midbrain/RAS (reticular activating system): centers for receiving and integrating several types of sensory info Corpus callosum: connects brain hemispheres From Wikipedia Evolutionary Trends More complex! This system is necessary for complexity and sophisticated behaviors/responses to environment Increases chance of survival: more complex NS = more complicated nerve connections, behaviors, movements The nervous system controls all other body systems!! Except maybe skeletal Neurons Neurons Sensory neurons Interneurons Motor neurons How Neurons work Resting potential: negative relative to the outside Sodium-potassium pumps in the plasma membrane Transport sodium out of the cell and potassium into it Very few sodium channels Net negative charge inside cell Action Potential Depolarization Rising phase of the action potential Falling phase of the action potential Undershoot: Potassium channels close to bring it back to the concentration needed to be at resting potential refractory period Conduction of the Action Potential Action potential: a “wave” from dendrite to axon Speed is determined by axon diameter Evolutionary trend: Because vertebrate axons have narrow diameters, vertebrates have adapted the myelin sheath to enable more efficient conduction Nodes of Ranvier (nodes between gaps in myelin sheath) allows for saltatory conduction current jumps from node to node Synapses Electrical synapses: contain gap junctions to allow electrical currents to flow from one neuron to another Chemical synapses (most synapses): neurotransmitter Examples of neurotransmitters: acetylcholine, biogenic amines (serotonin) Disorders and Diseases Cerebrovascular accident (stroke) Parkinson's disease: decreased stimulation of the motor cortex by the basal ganglia caused by the insufficient formation and action of dopamine Multiple sclerosis: immune system damages the myelin When myelin is lost, the axons can no longer effectively conduct signals Works Cited and Consulted AP Bio book http://faculty.washington.edu/chudler/nsdivide.html http://parasitology.informatik.uni wuerzburg.de/login/n/h/0941.html http://www.daviddarling.info/encyclopedia/V/vertebrat e_nervous_system.html http://infusion.allconet.org/webquest/PhylumMollusca. html http://www.mindcreators.com/Images/NB_Neuron.gif http://en.wikipedia.org/wiki/File:Neurons_big1.jpg