* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Chapter 23 (OLD)
Point mutation wikipedia , lookup
Genome (book) wikipedia , lookup
Gene expression programming wikipedia , lookup
Inbreeding avoidance wikipedia , lookup
Pharmacogenomics wikipedia , lookup
Designer baby wikipedia , lookup
Human leukocyte antigen wikipedia , lookup
Human genetic variation wikipedia , lookup
Koinophilia wikipedia , lookup
Polymorphism (biology) wikipedia , lookup
Dominance (genetics) wikipedia , lookup
Hardy–Weinberg principle wikipedia , lookup
Genetic drift wikipedia , lookup
Chapter 23 Diversity of Individuals and Evolution of Populations I. Evolution occurs with the gradual change in the allele frequency within a population over time a population of one species has a variety of individuals for any feature, there can be many phenotypes  phenotypes are determined by alleles  must examine change in allele frequency of a population over time  II. Examining population’s allele and genotype frequency to study evolution  population - localized group of individuals of the same species  species  gene - a group of populations that can interbreed pool - all alleles for all genes present in a population  genetic structure of a population - population frequency of alleles & genotypes III. Hardy-Weiberg theorem for a non-evolving population - a look at population structure  Assume a gene with 2 alleles: A and a  allele frequency is: A (0.8 = 80%) and a (0.2 = 20%)  chance of AA offspring = 0.8 x 0.8 = 0.64**  chance of aa offspring = 0.2 x 0.2 = 0.04**  chance of Aa offspring = (0.8 x 0.2) x 2 = 0.32 **  ** this would be expected genotype structure at equilibrium (Hardy-Weinberg equlibrium)  Assume a gene with 2 alleles: A and a  frequency of allele #1 (eg. A = 0.8) = p  frequency of allele #2 (eg. a = 0.2) = q of resulting in AA = p x p = p2  chance of resulting in aa = q x q = q2  chance of resulting in Aa = 2 (p x q) = 2 p q  chance  p2 + 2pq  allows + q2 = 1 us to calculate population structure IV. Evolution is - a generation-to-generation change in a population’s frequency of alleles and genotypes  change in the Hardy-Weinberg frequency over time is a sign that some alleles can result in a phenotype which gives a “selective” advantage over other alleles  for Hardy-Weinberg equilibrium to be maintained:  large population size must exist  no gene flow from other populations can occur  no net mutations can occur  random mating must be happening  no natural selection can be occurring V. Deviations from Hardy-Weinberg can result from:  genetic drift (population size)  gene flow  mutation results in new alleles  non-random mating (assortive mating, inbreeding)  natural selection (differential success of offspring) VI. Natural selection is dependent upon variation alleles that give rise to a variety of phenotypes  most phenotypes are the result of multiple genes  polymorphism - variation of a certain item for discussion  sources of polymorphism: genetic mutation - results in new and different alleles  recombination - results new combinations of alleles  VII. Fitness - the relative contribution of an individual to the population gene pool  Think  gene, about what is meant by the following: allele, genotype, phenotype  species  population  natural selection  allele and genotype structure of a population  evolution