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Health and Disease Disease • Change that disrupts the normal function of the body (not an injury) Disease is caused by: • Pathogens-disease producing agents – Bacteria- Streptococcus – Fungi- athletes foot, nail fungus – Worms- tapeworms, roundworms – Viruses- HIV, Common Cold – Protists- Plasmodium; malaria Bacteria• Domain- Eubacteria • Prokaryotic – NO nucleus • Single Celled • Has its own DNA – circular (plasmid) 3 Shapes: Bacilli, Cocci, and Spirilla 3 – Viruses• not a living thing • No cell structures or processes –Composed of: a core of DNA wrapped in a Protein coat called a, capsid – If they contain RNA instead, they are called retroviruses Pg. 479 Figure 19-9 • Types of Viruses • Reproduce inside living cells by forcing cell to make more viruses • Types: Colds, warts, HIV, influenza, smallpox – Protists• • • • Single Celled; Eukaryotes Some are plant-like- Euglena Some are animal-like- Amoeba Plasmodium causes Malaria Disease is also caused by: • Environmental Factors– – Diet- heart disease, diabetes Carcinogens –substances known to cause cancer- abnormal cells divide out of control • tobacco products, UV Rays, radiation skin cancer Disease is also caused by: • • Genetic factors- hemophilia, cystic fibrosis, PKU, sickle cell anemia Combination of factors- cancer, diabetes can be caused by genetic and environmental factors Disease is spread by: • • • Physical contact- touch, air, objects, sexual contact Contaminated food and water Animals – – – Dog- rabies Mosquitoes- malaria Tick- Lyme disease Fighting Infectious Disease • • • Antibiotics- compounds that kill bacteria but not host cells Antivirals- compounds that fight viral infections Body Defenses- 3 lines of defense – 1st Line of Defense -keeps pathogens out of the body • Skin **most important nonspecific defense**, mucus, tears, sweat, stomach acid and saliva (contain lysozyme) • Not specific- attacks any invader Fighting Infectious Disease – 2nd Line of Defense- cells or processes • Not specific- attack any foreign invader • White blood cellsPhagocytosis: ingest and digest • Inflammatory Resonsepain and swelling • Fever- increase in body temperature; slows or STOPS the growth of pathogen phagocytosis Fighting Infectious Disease – 3rd Line of Defense- Immune Response • • • • Specific for each foreign invader Antigen-substance that triggers an immune response B cells– produce antibodies- proteins that circulate in bloodstream and cause invader death – Provide memory when same invader is encountered again T cells Immune Response – Help activate B cells – Kill cancer or infected cells – Suppress immune response Types of Immunity – Active Immunity • vaccine (weakened or dead pathogens) or active infection • Stimulates immune system to create B cells ready to produce specific antibodies for the long term • Chicken pox infection, polio vaccine Types of Immunity – Passive Immunity • Antibodies produced elsewhere • Provides only short term protection • Mothers antibodies passed to fetus, snake antivenom given to bite victim