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Mendel’s Laws of Heredity Heredity • Heredity- the passing on of characteristics from parent to offspring • Characteristics that are inherited are called traits • Genetics- the branch of biology that studies heredity Gregor Mendel • In the mid-19th century, Gregor Mendel, an Austrian monk carried out important studies of heredity • He was the first to predict how traits are transferred from one generation to the next Mendel’s Pea Plants • His experiments were conducted using pea plants because: 1. The reproduce sexually through the formation of gametes 2. He could control fertilization, by pollinating the plants himself Monohybrid Crosses • A hybrid is the offspring of parents that have different forms of a trait, such as tall and short heights • Mendel’s 1st experiments are called monohybrid crosses because he looked at only one trait Parental Generation • Parental generation- P1- each parent plant was from other plants that displayed the same traits • He cross-pollinated the tall plant with the short plant First Generation • The offspring of the P1 cross are called the first generation or F1 generation • In this generation, all of the pea plants would be tall • In the F1 generation, it was as if the shorter parent had never existed Second Generation • Mendel allowed the tall plants from the F1 generation to self-pollinate • After the seeds formed, he planted them and counted more than 1000 plants in the second generation or F2 • Mendel found that ¾ of the plants were tall and ¼ of the offspring were short Rule of Unit Factors • Mendel concluded that each organism has two factors that control each of its traits • We now know that these factors are genes and that they are located on chromosomes • Genes exist in alternative forms, we call these different gene forms alleles • One allele is inherited from the mother and one is from the father Rule of Dominance • In Mendel’s crosses, the observed trait was referred to as dominant (T) • The trait that seemed to disappear was called recessive (t) • Dominant alleles are capitalized and recessive alleles are lower-case Law of Segregation • The law of segregation states that every individual has two alleles of each gene and when gametes are produced, each gamete receives one of these alleles • During fertilization, these gametes randomly pair to produce four combos of alleles Phenotypes • The way an organism looks and behaves is called its phenotypes • Therefore, two organisms can look alike but have different underlying allele combos, Tt or TT, either one will display a dominant phenotype Genotypes • The allele combination an organism contains is known as its genotype • The genotype of a tall plant that has two alleles for tallness is TT • The genotype of a tall plant that has one allele for tallness and one for shortness is Tt • An organism’s genotype can not always be seen Homozygous or Heterozygous • An organism is homozygous for a trait if its two alleles for the trait are the same -homozygous dominant (TT)- both code for tallness -homozygous recessive (tt)- both code for shortness • An organism is heterozygous for a trait if its two alleles for the trait differ from each other (Tt) Mendel’s Dihybrid Crosses • Mendel preformed another set of crosses in which he used peas that differed from each other in two traits rather than one • A cross involving two different traits is called a dihybrid cross Parental Generation • Mendel took true-breeding pea plants that had round, yellow seeds (RRYY) and crossed them with true-breeding pea plants that had wrinkled, green seeds (rryy) First Generation • He already knew that the F1 generation would have all plants displaying the dominant phenotypes; round, yellow seeds Second Generation • Mendel then let the F1 plants self-pollinate • As expected the recessive reappeared • When Mendel sorted and counted the plants of the F2 generation, he found they appeared in a definite ratio of phenotypes -9 round yellow: 3 round green: 3 wrinkled yellow: 1 wrinkled green Law of Independent Assortment • Mendel’s second law states that genes for different traits- for example, seed shape and seed color- are inherited independently of each other Punnett Squares • In 1905, Reginald Punnett, an English biologist, devised a shorthand way of finding the expected proportions of possible genotypes in the offspring of a cross • This method is called a Punnett Square Probability • Punnett squares are good for showing all the possible combos of gametes and the likelihood that each will occur • In reality, however, you don’t get the exact ratio of results shown in the square • Genetics is more like flipping a coin-it follows the rules of chance