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Growth and Development (B5) B5.1 How does an organism produce new cells? DNA has a double helix structure The cell cycle • Cell cycle: the main processes 1. Cell growth during which – The number of organelles increase – The chromosomes are copied when the two strands of each DNA molecule separate and new strands form alongside them 2. Mitosis during which – Copies of the chromosomes separate – The cell divides 1. Cell growth during which – The number of organelles increase – The chromosomes are copied when the two strands of each DNA molecule separate and new strands form alongside them 2. Mitosis during which –Copies of the chromosomes separate –The cell divides • Cell Division by Mitosis: this produces two new cells identical to each other and to the parent cell How does an organism produce new cells? There are two types of cell division: Mitosis M_______ Meiosis M_______ Meiosis • A type of cell division that produces gametes • It is important in meiosis that the cells produced only contain half the chromosome number of the parent cell. • A zygote contains a set of chromosomes from each parent Meiosis Gametes Zygote Questions • What happens in the normal cell cycle? –Cell growth –Mitosis • What happens during cell growth? –Number of organelles increase –Chromosomes are copied by separating DNA strands and forming new strands • What happens during Mitosis? –Copies of the chromosomes separate –The cell divides More questions • In which organs do cells divide by Meiosis? – Ovaries and Testes • How many chromosomes are in the gamete if the parent cell has 46? – 23 • How many chromosomes does the zygote have? Where are they from? – 46 – A set from each gamete. (from each parent) Growth and Development (B5) B5.2 How do genes control growth and development within the cell? DNA - the genetic code • The genetic code is in the cell nucleus BUT proteins are produced in the cell cytoplasm Nucleus Cytoplasm Genes do not leave the nucleus but a copy of the gene is produced to carry the genetic code to the cytoplasm In the nucleus Travels to the cytoplasm In the cytoplasm Both strands of DNA are made up of four different bases. The bases always pair up in the same way A -T C-G The Genetic Code The order of the bases in a gene is the code for building up amino acids in the correct order to make a particular protein Chromosome made of DNA In mRNA U (not T) mRNA copy of gene Protein made of amino acids Questions Where are proteins made in cells? In the cytoplasm Where is the genetic code found? In the nucleus of every cell How does the code get into the cytoplasm? A copy of the gene carries the code (RNA) How many different bases are in DNA? Four different bases, always pairing the same way How is the order of the amino acids in proteins determined? The order of bases in a gene is the code Growth and Development (B5) B5.3 How do new organisms develop from a single cell? Early embryos The zygote divides by mitosis to form an embryo In a human embryo, up to the eight cell stage, all the cells are identical and could produce any sort of cell required by the organism (embryonic stem cells) After this point the cells become specialised and form different types of tissue. Some of the genes are switched off. Specialised Cells After this point the cells become specialised and form different types of tissue Although body cells in an organism contain the same genes, many genes in a particular cell are not active because it only produces the specific proteins it needs One cell type becomes many! Gene switches •Gene for insulin is on in the pancreas but off in the kidney •Gene for ADH is on in the pituitary gland but off in the salivary gland gametes zygote mitosis Specialised cell types in tissues Cloning • In carefully controlled conditions of mammalian cloning, it is possible to reactivate inactive genes in the nucleus of a body cell to form cells of all tissue types. • Adult and embryonic stem cells have the potential to produce cells needed to replace damaged tissues. Plants from from single cells • New cells in plants specialise into cells of roots, leaves or flowers. Unlike animal cells some plant cells remain unspecialised and can develop into any type of plant cell. These unspecialised cells allow the production of clones of plants with desirable features, from cuttings. Plant meristems • Plant meristems divide to produce cells that result in increased height, length of roots and girth of the plant. If the hormonal conditions in their environment are changed, unspecialised plant cells can develop into a range of other tissues (eg xylem and phloem) or organs (eg leaves, roots, flowers) Cut stems from a plant can develop roots in the presence of plant hormones (auxins) and grow into a complete plant which is a clone of the parent Phototropism Phototropism is the plant’s response to light. It increases the plant’s chance of survival Light causes auxin to move to the opposite side of the shoot tip. The cells on the side with more auxin grow bigger. REVISE Check your knowledge Growth and Development (B5) B5.1 How does an organism produce new cells? double helix DNA has a ____________ structure The Cell Cycle • Cell cycle: the main processes 1. Cell growth during which The number of organelles increase - -______________________________ -___________________________ The chromosomes are copied when the two strands of each DNA molecule separate and new strands form alongside them 2. Mitosis during which – Copies ____________________________ of the chromosomes separate – The ____________________________ cell divides 1. – – Cell growth during which The number of organelles increase _______________________________ ____________________________ The chromosomes are copied when the two strands of each DNA molecule separate and new strands form alongside them 2. Mitosis during which ____________________________ —Copies of the chromosomes separate — The cell divides _______________________ • Cell Division by Mitosis: this two new cells identical produces ____ to each other and to the parent cell How does an organism produce new cells? There are two types of cell division: Mitosis M_______ Meiosis M_______ Meiosis • A type of cell division that produces gametes • It is important in meiosis that the cells produced only contain half the chromosome number of the parent cell. • A zygote contains a set of chromosomes from each parent Meiosis Gametes Zygote Questions • What happens in the normal cell cycle? –Cell growth –Mitosis • What happens during cell growth? –Number of organelles increase –Chromosomes are copied by separating DNA strands and forming new strands • What happens during Mitosis? –Copies of the chromosomes separate –The cell divides More questions • In which organs do cells divide by Meiosis? – Ovaries and Testes • How many chromosomes are in the gamete if the parent cell has 46? – 23 • How many chromosomes does the zygote have? Where are they from? – 46 – A set from each gamete. (from each parent) Growth and Development (B5) B5.2 How do genes control growth and development within the cell? DNA - the genetic code cell nucleus • The genetic code is in the ________ BUT proteins are produced in the cell cytoplasm __________. Nucleus Cytoplasm copy of the gene Genes do not leave the nucleus but a _______________ is produced to carry the genetic code to the cytoplasm In the nucleus Travels to the cytoplasm In the cytoplasm Both strands of DNA are made up of ____ four different bases. The bases always pair up _______________ in the same way A-T ? C -G ? The Genetic Code order of the bases The _____________________ in a gene is the code for building up amino acids in the protein correct order to make a particular ________. Chromosome DNA made of ____ In mRNA __ U (not T) mRNA copy ____ __________ of gene Protein made of amino __________. acids Questions Where are proteins made in cells? In the cytoplasm Where is the genetic code found? In the nucleus of every cell How does the code get into the cytoplasm? A copy of the gene carries the code (RNA) How many different bases are in DNA? Four different bases, always pairing the same way How is the order of the amino acids in proteins determined? The order of bases in a gene is the code Growth and Development (B5) B5.3 How do new organisms develop from a single cell? Early embryos The zygote divides by ________ mitosis to form an embryo In a human embryo, up to the _____ eight _____ cell stage, all the cells are identical and could produce any sort of cell required by the organism (embryonic stem cells) After this point the cells become specialised __________ and form different types of tissue _________. Specialised Cells After this point the cells become specialised ________ and form different types of tissue ________. Although body cells in an organism contain the same genes, many genes in a particular cell are _________ because not activeit only produces the specific _________ itproteins needs One cell type becomes many! Gene switches •Gene for insulin is on in pancreas the _________ but off in the kidney •Gene for ADH is on in the pituitary gland ____________ but off in the salivary gland gametes zygote mitosis Specialised cell types in tissues Cloning • In carefully controlled conditions of mammalian cloning, it is possible to reactivate inactive genes in the nucleus __________ of a body cell to form cells of all tissue types. stem cells have • Adult and embryonic _________ the potential to produce cells needed to replace damaged tissues. Plants from from single cells • New cells in plants specialise into cells flowers of roots, leaves or ________. Unlike animal cells some plant cells remain unspecialised ____________ and can develop into any type of plant cell. These unspecialised cells allow the clones production of _______ of plants with desirable features, from cuttings _______. Plant meristems • Plant meristems divide to produce cells that result in increased ___________________ height, length of roots and ______ girth of the plant. If the hormonal conditions in their environment are changed, unspecialised plant cells can develop into a range xylem and phloem of other tissues (eg _____________________) or organs (eg leaves, roots, flowers ____________________) Plant Hormones roots in the Cut stems from a plant can develop _______ auxins and grow into a presence of plant hormones (________) clone of the parent complete plant which is a _______ Phototropism the plant’s response to light Phototropism is _________________________. survival It increases the plant’s chance of _________. auxin to move to the opposite side of Light causes ______ the shoot tip. The cells on the side with more auxin bigger grow ______. Questions two cells. Division of a cell by mitosis creates ____ When do mammalian embryonic cells become specialised? The eight cell stage How do cells control which proteins they produce? They can inactivate genes or reactivate inactivated genes. If animal stem cells can produce cells to replace damaged tissues, what can plant stem cells do? Develop into any type of plant cell