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Protein synthesis Translation Things to know… • Structure and function of tRNA • Structure and function of ribosome • Stages of translation – Initiation – Elongation – Termination • Types of RNA • Mutations can change products Figure 17.12 Translation: the basic concept Figure 17.13a The structure of transfer RNA (tRNA) Figure 17.13b The structure of transfer RNA (tRNA) Figure 17.4 The dictionary of the genetic code Figure 17.5 A tobacco plant expressing a firefly gene Figure 17.14 An aminoacyl-tRNA synthetase joins a specific amino acid to a tRNA Figure 17.15 The anatomy of a functioning ribosome Figure 17.17 The initiation of translation Figure 17.18 The elongation cycle of translation Figure 17.19 The termination of translation Figure 17.20 Polyribosomes DO NOW: on small paper • Identify the difference(s) between ribosomes in cytoplasm and on ER. • Can cytoplasmic and ER ribosomes ever change places? If so, when? ER Protein Targeting Table 17.1 Types of RNA in a Eukaryotic Cell Figure 17.22 Coupled transcription and translation in bacteria Figure 17.23 The molecular basis of sickle-cell disease: a point mutation Figure 17.24 Categories and consequences of point mutations: Base-pair insertion or deletion Figure 17.24 Categories and consequences of point mutations: Base-pair substitution Figure 17.25 A summary of transcription and translation in a eukaryotic cell