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Biochemistry Carbon Compounds Why carbon? – – – Has four valence electrons These can join with four more electrons from other atoms Can bond with other carbon atoms Macromolecules Giant molecules Formed by polymerization – large molecules built by joining smaller ones together – – Monomers: small units Polymers: 3 or more small units together Types of Macromolecules Four groups of organic compounds – – – – Carbohydrates Lipids Nucleic acids Proteins Carbohydrates Made of carbon, hydrogen, oxygen 1:2:1 ratio of above elements Living things use carbohydrates as main source of energy Carbs, cont. Simple sugars = MONOSACCHARIDES Glucose, galactose (milk), fructose (fruits) Large molecules = POLYSACCHARIDES Glycogen = animal starch, in liver Cellulose = plant starch Lipids Made mostly of carbon and hydrogen Fats, oils and waxes Used to store energy 2 parts: glycerol and fatty acids 2 main types: – – – Saturated: maximum number of hydrogen atoms Unsaturated: at least 1 carbon to carbon bond Polyunsaturated: more than one carbon to carbon bond Nucleic Acids Macromolecules containing H, O, N, C, P Store and transmit hereditary information – – DNA – deoxyribonucleic acid; sugar is deoxyribose RNA – ribonucleic acid; sugar is ribose Monomers called nucleotides – 3 parts: 5-carbon sugar Phosphate group Nitrogenous base Proteins Macromolecules contain C, H, O, N Polymers made of monomers called – Amino Acids (there are 20 of them) Various jobs: – – – – – Control rate of reactions in cells Regulate cell processes Used to form bone and muscle Transport substances in and out of cells Help fight disease Proteins, cont. Four levels of organization – – – – 1. sequence of amino acids in a chain 2. can be twisted or folded 3. chain itself is folded 4. can have more than one chain, folded around each other Chemical Reactions Chemical Reactions Process that changes one set of chemicals into another set of chemicals – – Rust Hydrogen and oxygen Reactants: elements or compounds that enter into a chemical reaction Products: elements or compounds produced by a chemical reaction Energy in Reactions Energy is either released or absorbed when chemical bonds are made or broken – – If release energy, occur spontaneously If absorb energy, need a source of energy In living things, need to carry out reactions that require energy – – Plants – sunlight Animals -- food Enzymes Some chemical reactions in living things are too slow, or too fast Cells make catalysts – – Speeds up rate of reaction If energy too high then lowers that energy Enzymes = proteins that act as biological catalysts – Lowers the energy needed for a reaction to take place Enzymes, cont. They are very specific; only works on one chemical reaction They get their name from the reaction Enzymes in action Enzyme Action Enzyme-Substrate Complex – – Enzymes provide a site where reactants can be brought together Reduces the amount of energy needed for reaction Substrate = what is broken down Active site = where substrate binds on the enzyme Lock-and-key model Enzymes, cont. What affects enzyme activity – – pH Temperature