Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Protein folding wikipedia , lookup
Circular dichroism wikipedia , lookup
Nuclear magnetic resonance spectroscopy of proteins wikipedia , lookup
Protein–protein interaction wikipedia , lookup
Western blot wikipedia , lookup
Protein mass spectrometry wikipedia , lookup
List of types of proteins wikipedia , lookup
Intrinsically disordered proteins wikipedia , lookup
Regents Biology Proteins: _________________________ Regents Biology 2006-2007 Proteins Examples ______________________ ______________________ collagen, keratin insulin pepsin ______________________ digestive enzyme in stomach ______________________ hormone that controls blood sugar levels Regents Biology collagen (skin) Proteins Function: many, many functions ________________________ signals from one body system to another insulin ________________________ muscle ________________________ protect against germs ________________________ help chemical reactions Regents Biology Proteins Building block = __________________ amino amino amino amino amino acid – acid – acid – acid – acid ________________________ H O H | || —N— —C—C—OH | H variable Regents Biology group There’s 20 of us… like 20 different letters in an alphabet! Can make lots of different words Amino acid chains Proteins amino acids chained into a polymer amino acid amino acid amino acid amino acid amino acid Each amino acid is different __________________________________ __________________________________ Regents Biology Water-fearing amino acids Hydrophobic __________________________________ try to get away from water in cell the protein folds Regents Biology Water-loving amino acids Hydrophillic __________________________________ try to stay in water in cell the protein folds Regents Biology For proteins: SHAPE matters! ___________________________________ that’s what happens in the cell! ___________________________________ growth hormone Regents Biology hemoglobin pepsin collagen It’s SHAPE that matters! __________________________________ __________________________________ Unfolding a protein destroys its shape wrong shape = _____________________ unfolding proteins = ________________ temperature pH (acidity) folded In Biology, it’s not the size, it’s the SHAPE that matters! Regents Biology unfolded “denatured” Let’s eat some Proteins! Regents Biology 2006-2007