Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Centennial Honors College Western Illinois University Undergraduate Research Day 2012 Poster Presentation Development of a Convenient and Pedagogically Useful Green Oxidation Protocol for Wider Adaptation in Undergraduate Laboratory Curriculum Shanique Ries Faculty Mentor: T. K. Vinod Chemistry Use of well-known reagents for the oxidation of different functional groups and the mechanism of such transformations are an important part of any sophomore organic chemistry curriculum. Most, if not all, of the traditional oxidizing agents covered in an undergraduate lecture course are transition metal based reagents which are toxic and are also potential environmental pollutants. While the ease and efficiency (% yield) of the oxidation reactions using these reagents are highlighted during the lecture class, the deleterious health and environmental aspects of these reagents are often ignored or omitted in classroom discussions. A green oxidation procedure for oxidation of alcohols using catalytic amounts of in-situ generated o-iodoxybenzoic acid (IBX) in presence of Oxone as a stoichiometric oxidant is developed. Catalytic amount of commercially available 2-iodobenzoic acid is used as the organoiodine precursor for IBX in the reaction. This convenient procedure for the oxidation of alcohols, completed in a 2.5 h laboratory period, is carried out in aqueous solvent mixtures. Students are introduced to several pedagogically relevant green chemistry principles including the use of aqueous reaction medium, non-extractive product isolation procedure, and use of benign and catalytic reagents through this convenient oxidation experiment. Finally, this experiment also allow instructors to discuss the use of IBX and other hypervalent iodine reagents as benign alternatives to commonly used and frequently discussed transition metal based reagents.