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2008-2009 Responsible Conduct of Research Workshop Program Responsible Decision-making in Academic Research: Ethical and Moral Perspectives - September 25, 2008 - RESPONSE SLIDES – Which of the following describes best your disciplinary academic affiliation? You will know that your response is received by the 3second long green light signal on your ResponseCard® Radio Frequency Keypad (can rest or be held anywhere). Please return ResponseCards at the end of the Workshop. Thank You! 0% 0% 0% 0% 0% 0% 0% 0% 0% 0 of 5 1. 2. 3. 4. 5. 6. 7. 8. 9. Arts & Humanities Clinical Programs Education Engineering & other Technical Disciplines Life Sciences Physical Sciences Social Sciences Professional Programs Other Choose Now Please indicate the number of courses you have taken either as an undergraduate of graduate student that emphasized aspects of moral or ethical reasoning OR professional ethics. 0% 0% 0% 0% 0% 0% 0% 0 of 5 1. 2. 3. 4. 5. 6. 7. None One Two Three Four Five Six or more Answer Now Doing the sham surgery (and exposing patients to some small risk of infection or the risks of general anesthesia) is morally permissible in order to achieve as high a degree of certainty as possible with regard to the efficacy of the real surgery; the placebo effect is real and can otherwise distort our understanding of the effectiveness of the intervention. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. Scenario Juries are a vital part of protecting justice within our criminal justice system. People can spend decades in prison as a result of what those juries decide. But those deliberations are largely hidden from public scientific scrutiny, which means that if there are substantial flaws in their deliberations those flaws will go undetected and uncorrected. I would endorse a social science research project that would secretly videotape jury deliberations with the goal of improving the quality of that deliberative process through careful scientific analysis of those deliberations. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. If you were a third year graduate student in sociology or psychology, and if your research assistantship involved reviewing the videotapes of jury deliberations described above (coding the language and behavior of the jurors), then even if you have some ethical concerns about this research, it would still be morally permissible for you to continue since you would otherwise lose your graduate assistantship. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. Scenario Jacob Sontag is 18 months old and has Canavan’s disease, a degenerative brain disorder. Such children lack a key enzyme needed to break down an acid in the brain known as NAA. This is because of a genetic defect. Such children will die before age ten. Autopsy will reveal a spongy brain full of tiny holes. Two bright new researchers at Yale had proposed doing gene therapy for Canavan’s. They had tested their methods on 300 rats, 4 monkeys, and 2 children in New Zealand. They wanted the opportunity to shoot a syringe full of healthy genes into Jacob’s brain, but three university research oversight committees were reluctant to approve the research. These are desperate parents trying to save the life of a child they love. From a moral point of view there is no justification for a delay by the IRB (and the other university committees) and their vague concerns about safety since this child has a terminal prognosis and no alternative therapy options. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. From a moral point of view there is no justification for using vertebrate animals (rats, mice, rabbits, etc.) as research subjects. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. From a moral point of view there is no justification for using vertebrate animals (rats, mice, rabbits, etc.) as research subjects to study chronic pain without` medication. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. MIT Computer Engineering students identified ways to hack into and avoid paying required MTA rider fees because of a glitch in the MTA’s computer system. From a moral point of view there is nothing wrong with publishing these findings in a computer journal. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. The Grand Canyon National Park has funded a project to map and interpret “Rock Art” within the Park. From a moral point of view there is nothing wrong with publishing the locations of this art in a computer journal. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5. If the courts are going to allow exclusive patents for a broad range of genetic tests, then universities need to jump on this bandwagon and obtain these patents themselves in order to realize the potential revenues available. This is what Miami Children’s Hospital did with a genetic test for Canavan’s disease, earning them $12 in royalties each time that test is used. There is nothing unethical about such ordinary business behavior. Strongly Agree Agree Neutral Disagree Strongly Disagree Answer Now 0% ag re e 0% ly D Di s is a gr ee tra l 0% eu A gr ee 0% St ro ng 0 of 5 St ro ng ly Ag re e 0% N 1. 2. 3. 4. 5.