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Cell Division & Mitosis Yay Getting closer and closer to the FUN stuff!!! Cell Division • What is cell division? – Process where a cell splits into 2 individual daughter cells • Why do we need cell division? New cells are produced for growth and to replace damaged or old cells • There are 2 major types – Mitosis- division of the NUCLEUS – Cytokinesis- division of the CYTOPLASM DNA Replication Replication = COPY Original DNA DNA must be strand copied or replicated before Two new, cell division identical DNA strands Each new cell will then have an identical copy of the DNA copyright cmassengale 3 Identical Daughter Cells Two identical daughter cells Parent Cell copyright cmassengale 4 Chromosomes • These are super important little friends • Here are some defining characteristics – Made of tightly coiled DNA – Found in the NUCLEUS – The number depends on the organism they live in… usually 10-50 – Humans have 46 chromosomes in pairs (23 pairs) Chromosomes in Dividing Cells chromosomes are made of 2 chromatids that are held together by the centromere Called Sister Chromatids copyright cmassengale 6 Types of Cell Reproduction Asexual reproduction -1 cell dividing to make 2 new, identical daughter cells ex. Mitosis & Binary Fission Sexual reproduction- two cells (egg & sperm) making new cell (zygote) that is NOT identical to the original ex. Meiosis copyright cmassengale 7 Cell Division in Prokaryotes Prokaryotes (bacteria) divide into 2 identical cells through binary fission Parent cell Chromosome replicates Cell splits copyright cmassengale 2 identical daughter cells 8 The cell cycle • Cell Cycle- events cells go through as they grow and divide • The cell cycle consists of five phases: – G1 (Primary Growth Phase) • Cell increases in size – S Phase (Synthesis) • Chromosomes are replicated – G2 (Second Growth Phase) • Organelles are produced – M Phase • MITOSIS – Cytokinesis These three phases are known as Interphase Sketch me!!! Interphase • Not technically a part of mitosis • Includes G1, S, and G2 • Organelles double in number to prepare for division Mitosis- Division of the nucleus • These are the phases – – – – Prophase Metaphase Anaphase Telophase Four Mitotic Stages Prophase Metaphase Anaphase Telophase copyright cmassengale 12 Prophase • Spindle fibers form • Centrioles move to opposite poles • Chromosomes become visible Metaphase • Chromosomes line up at the EQUATOR Anaphase • Centromeres divide • Chromatids separate and move to the opposite poles Telophase • Nuclear membrane forms around each of the chromosomes • Chromosomes unwind • Cytokinesis begins Cytokinesis • Cytoplasm divides and one cell becomes two individual cells. The difference ANIMALS Extra credit! Cleavage Furrow is formed PLANTS Extra Credit Cell Plate is formed Cytokinesis Cleavage furrow in animal cell Cell plate in plant cell copyright cmassengale 19 Mitosis in Onion Root Tips Do you see any stages of mitosis? copyright cmassengale 20 Karyotype A picture of the chromosomes from a human cell arranged in pairs by size Remember this! We’ll make one of these after Christmas! copyright cmassengale 21