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THE ALIMENTARY CANAL: DIGESTION AND ABSORPTION CHAPTER 3 Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. Components of the Alimentary Tract Oral cavity Pharynx Esophagus Stomach Small intestine Duodenum Jejunum Ileum Large intestine Cecum Colon Rectum Accessory organs: Salivary glands Liver Gallbladder Pancreas Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 2 Digestion of Food Chemical actions Reduce foodstuffs to absorbable molecules Enzymes Mechanical actions Break up and mix foods, permitting better blending with the chemicals Chewing Peristalsis Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 3 Process of Nutrition: Oral Cavity Food choices influenced by the three sensory perceptions: Sight Smell Taste The oral cavity is the “port of entry” where receptors for the sense of taste or taste buds are located Taste bud consists of 30 to 100 cells Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 4 Process of Nutrition: Oral Cavity Mechanical digestion Begins w/biting and chewing food Smaller food pieces provide more surface area for digestive enzymes to function Chemical digestion Salivary amylase Allows large molecule carbohydrates, which are not fermentable by plaque acids, to be hydrolyzed into shorter chains that are fermentable Saliva containing mucus causes food to stick together into a bolus; lubricates the mass for swallowing From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 5 Process of Nutrition: Esophagus No digestion occurs The bolus passes back to the pharynx under voluntary control The process then becomes involuntary Peristalsis moves the food rapidly to the stomach From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 6 Process of Nutrition: Stomach Stomach secretions Chief cells produce pepsinogen Parietal cells release HCl to make gastric contents acidic (1.5 to 3 pH) Halts the action of salivary amylase Aids in absorption of minerals like calcium, iron, zinc Kills or inhibits growth of food bacteria Secrete intrinsic factor to aid absorption of vitamin B12 From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Pepsinogen and HCl work together to begin hydrolysis of protein Gastric lipase to digest short- and medium-chain fatty acids (FAs) Stomach empties in 1 to 4 hrs depending on amount and types of food eaten Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 7 Process of Nutrition: Small Intestine Digestion Acidic chyme from the stomach stimulates the release of pancreatic enzymes CHOs: pancreatic amylase Protein: trypsin, chymotrypsin, carboxypeptidase Fat: lipase Microvilli in intestinal wall produce: Lactase, sucrase, and maltase: CHOs Aminopeptidase and dipeptidase: proteins Lipase: fats Bile produced by the liver and stored in the gallbladder aids in emulsification of fats Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 8 Process of Nutrition: Small Intestine–Absorption Means of transport (3 to 10 hr transit time) Active Carrier systems require energy, e.g., intrinsic factor Pumps require energy, e.g., absorption of glucose, Na, K, Mg, P, I, Ca, Fe, and amino acids Pinocytosis: engulfing of small drops of intestinal contents Allows for absorption of whole proteins, such as immunoglobulins in breast milk Passive Diffusion Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 9 Process of Nutrition: Small Intestine–Absorption Duodenum Electrolytes Minerals (Fe, Ca, Mg, Zn) Jejunum Water-soluble vitamins (C, thiamine, riboflavin, B6, folic acid) Mono- and disaccharides Ileum Protein Fat-soluble vitamins Fat/cholesterol Vitamin B12 From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 10 Process of Nutrition: Large Intestine Cecum (proximal portion) Water Electrolytes: Na and K Colon Additional digestion of materials occurs Several nutrients are formed by bacterial synthesis during the process including vitamins K and B12, thiamine, riboflavin Intestinal flora ferment CHO and fiber Rectum Anal canal Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 11 Dental Hygiene Considerations Assess nutritional status of patients with gustatory or olfactory disorders for changes in dietary habits Monitor quality and quantity of food intake for patients with difficulty chewing and swallowing food Heartburn: result of regurgitation (gastroesophageal reflux) of stomach contents into the esophagus Over an extended time, chronic problems with vomiting or reflux can result in sensitive teeth and superficial or deep tooth erosion, especially on lingual and occlusal surfaces Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 12 Practical Application A patient has had a gastric bypass that removes the lower portion of the stomach and much of the duodenum and jejunum Give a rationale for which nutrients might be affected From Mahan LK, Escott-Stump S: Krause’s Food and Nutrition Therapy, ed 13. St. Louis: Saunders, 2012. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 13 Practical Application A patient has reactions to gluten Discuss the three main conditions related to gluten allergies Give a rationale for which foods might best be avoided by patients with this sensitivity What nutrient absorption might be affected for these patients? How would you counsel them regarding nutrition? From Standring S: Gray's anatomy: the anatomical basis of clinical practice, ed 40, London, 2009, Churchill Livingstone. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 14