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Human Anatomy and Physiology The Digestive System The Digestive System - Function • Dissembles food to small molecules that the body can absorb. • Components: – Mouth, pharynx, esophagus stomach, small intestine, large intestine – Accessory structures: Salivary glands, pancreas, liver. These add secretions Digestive System • Total length 8-9 meters – 2/3 small intestines The digestive system Mouth Pharynx Salivary glands Esophagus Liver Gallbladder (behind liver) Rectum Stomach Pancreas (behind stomach) Large intestine Small intestine Upper Digestive System • Lips, Mouth (lips, tongue, teeth), salivary glands, pharynx, esophogus, Mouth • Mechanical and Chemical Digestion – Mastication – “chewing” • Lips – hold food in • Tongue – moves food around • Teeth – cut, tear and crush – Salivation – chemical digestion begins • Moistens food – salt, water, mucous • Amylase – starch breakdown to sugars • Lysozyme – breaks down cells (especially pathogens) • End result: Bolus – Bolus pushed to esophagus – Tongue and throat muscles Salivary Glands and Pharynx • Salivary glands – Three pairs • Parotid • Submandibular • Sublingual • Pharynx • Common passage • Epiglottis • Covering for the glottis (opening to the larynx) Esophogus – about 25 cm (10 inches) • Peristalsis – Movements in the “food tube” that push food to the stomach (voluntary muscle) • Can eat in no gravity • Can eat lying down • Cardiac Sphincter (involuntary) – Ring of muscle between stomach and esophagus – Heartburn; acid reflux • Overeating, high acid foods, high caffeine Stomach • Muscular sac • Chemical Digestion • Mucus – lubricates and protects the stomach wall • Hydrochloric acid – provides acidity • Pepsin – Activated by HCl – Begins protein digestion (with HCl) • Muscular Digestion – Fluids and food mix to form chyme – After ~1 to several hours, goes through pyloric valve to duodenum (1st part of small intestine) Ulcers • Caused by Helicobacter pylori – Requires antibiotics, not bland diets – Bacteria damage cells of stomach lining, make stomach susceptible to ulcers, acid further irritates. Duodenum • 1st part of small intestine • Most chemical digestion here – Enzymes & digestive juices from pancreas, liver, and duodenum lining Digestive System Site Enzyme Salivary amylase Mouth Stomach Pepsin Small intestine (from pancreas) Amylase Trypsin Lipase Small intestine Maltase, sucrase, lactase Peptidase Role in Digestion Breaks down starches into disaccharides Breaks down proteins into large peptides Continues the breakdown of starch Continues the breakdown of protein Breaks down fat Breaks down remaining disaccharides into monosaccharides Breaks down dipeptides into amino acids. Pancreas and Liver • As chyme enters duodenum of small intestine, add from: • Pancreas – For digestion: • Amylase – continued starch breakdown • Trypsin – protein; • Lipase – fat breakdown • Sodium bicarbonate – neutralizes stomach acid – Also: Enzymes that regulate blood sugar levels. • Liver – Bile – acts like a detergent • Disperses fat into droplets • Lipase then breaks down fats • Gall bladder – Bile storage area The liver and pancreas Section 38-2 Liver Gallbladder Duodenum Bile duct Pancreas Pancreatic duct To small intestine Small Intestine • Three parts – Duodenum – very short (< 1 meter) – Jejunum (3 meters) – Ileum (3 meters) • Role: Absorption of nutrients – Folds - Villi Microvilli • Contain capillary fields • Chyme moved slowly across surface • Absorb protein and carbohydrate products – Lacteals • Lymph vessels which absorb fatty acids and undigested fats Villus Small Intestine Circular folds Villi Epithelial cells Capillaries Lacteal Vein Artery Large Intestine • What remains? – Cellulose and undigested materials – Water – Bacteria • Purpose: Water absorption – Some vitamins produced here (K) • Defecation – Elimination of remaining waste material through rectum. (Solid excretion) Key Functions of Digestion • • • • • • • Mastication (Mechanical) Salivation (Chemical) Peristalsis (Mechanical) Actions of Enzymes/Acid (Chemical) Muscular Digestion (Mechanical) Absorption Defecation