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Fat-soluble organic compound found principally in certain plant oils and leaves of green vegetables Consists of eight chemical forms but only alpha-tocopherol meets human requirement Functions in the Body • Vitamin E is a powerful antioxidant and anti-carcinogen as well as anti-aging supplement. • Due to its antioxidant capabilities Vitamin E protects our body from: o • • • • carbon, lead, mercury, tetrachloride, the ozone, nitrous oxide and other carcinogens. Helps skin and scar tissue heal. Prevention of cancer. Assists in the maintenance of vitamins A and C in the body. Enhances antibody formation and benefits people suffering from a cold or other viruses. • Essential for cardiovascular health and for sex organ functioning. • Maintains the integrity of cell membranes. • Generally seen in: o o o premature infants individuals with genetic abnormalities those who cannot digest fat • Vitamin E Deficiency Symptoms in Infants o o o o Loss of weight and delayed growth Poor feeding habits Developmental problems that includes physical and mental problems Retrolental fibroplasia: Eye disease thought to be caused by disorganized growth of retinal blood vessels result in scarring and retinal detachment. May lead to blindness in serious cases. • Vitamin E Deficiency Symptoms in Children o Spinocerebellar ataxia with loss of deep tendon reflexes o Truncal and limb ataxia o Loss of vibration and position senses o Ophthalmoplegia Paralysis or weakness of one or more of the muscles that control eye movement o Muscle weakness o Ptosis abnormally low position (drooping) of the upper eyelid. o Dysarthria difficulty in articulation of words due to neurologic disturbances of function of orofacial muscles, tongue, lips, and throat. o Slow growth in children • Vitamin E Deficiency Symptoms in Adults Mild hemolytic anemia Abnormal breakdown of RBC’s o Nonspecific neurological deficits o Disorders related to reproduction and infertility o Fragile red blood cells o Age spots o Cataracts clouding that develops in the crystalline lens of the eye or in its envelope, varying in degree from slight to complete opacity and obstructing the passage of light. o Certain Neurological damage o Decrease in sex drive o Muscle, liver, bone marrow and brain function abnormalities. o • Take relatively large amounts for months to years without any apparent harm. • Occasionally, muscle weakness, fatigue, nausea, diarrhea and bleeding. • May increase the risk of hemorrhagic stroke and premature death. o accumulation of blood anywhere within the skull vault. • Particularly high levels of vitamin E can be found in the following foods o o o o o o o o o Asparagus Avocado Egg Milk Nuts (almonds or hazelnuts) Seeds Green Leafy Vegetables (spinach) Wholegrain foods Vegetable Oil • One quarter of whites and Hispanics, nearly one-half of African-Americans, and onethird of other ethnic groups have Vitamin E levels which place them at greater risk of cardiovascular disease. • Three national and the Continuing Survey of Food Intakes by Individuals have found that the diets of most Americans provide less than the RDA levels of vitamin E. • Because the digestive tract requires fat to absorb vitamin E, people with fatmalabsorption disorders are more likely to become The following populations may be at risk for vitamin E deficiency • People with Crohn’s disease, Cystic Fibrosis, Celiac Disease , pancreatic enzyme deficiency, and liver disease. • Very low birth weight infants—These infants are usually under the care of a neonatologist, who will evaluate and treat the premature infant's exact nutrition needs. • People who suffer from abetalipoproteinemia—This is a rare inherited disorder of fat metabolism that results in poor absorption of dietary fat and vitamin E. • Patients on Dialysis ,chronic parenteral nutrition and patients after Gastric Bypass surgery • http://ods.od.nih.gov/FACTSHEETS/VITAMINE.A SP • http://www.mbmc.org/healthgate/GetHGContent. aspx?token=9c315661-83b7-472d-a7abbc8582171f86&chunkiid=14070 • http://dietarysupplements.info.nih.gov/factsheets/vitamine.asp • http://www.the-vitamin-and-supplementguide.com/evitaminfunctions.html • http://ods.od.nih.gov/FACTSHEETS/VITAMINE.A SP • http://www.buzzle.com/articles/vitamin-edeficiency-symptoms.html