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January 25, 2012 January 20, 2012 Day 2 Objective: Understand how the endocrine system works by learning about diseases of the system Homework: None Bell Ringer: 1. What is the scientific name for the organs of the endocrine system? 2. What is the scientific name for the chemicals the endocrine system secretes? January 25, 2012 Slide 1 • ENDOCRINE SYSTEM- ON A MOLECULAR LEVEL The endocrine system is one of the more difficult systems you will learn about in class. Most of the activities of the system are not seen, and you probably do not know anything is happening. Most of the early information about the endocrine system came from studying things that went wrong with the system. Even today, there are still many mysteries related to this system and it’s activities. The best description we can offer is to describe the endocrine system as the chemical brother of the nervous system. While the nervous system transmits information and instructions using electricity, the endocrine system transmits information with chemicals. January 25, 2012 Understand how the endocrine system works by learning about diseases of the system January 25, 2012 http://www.linkstudio.info/images/portfolio/medani/Swallow.swf http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter26/animation__organs_of_digestion.html January 25, 2012 Slide 2 WHAT DOES THE ENDOCRINE SYSTEM DO? 1. The endocrine system controls many of the biochemical pathways that occur in your body. 2. The endocrine system produces hormones. 3. Your body uses dozens of hormones to regulate your growth, digestion, body temperature, glucose metabolism (to name a few). January 25, 2012 Slide 3 The Major glands of the endocrine system are listed above. Most of the endocrine organ names end in “Gland”. NOTE: The hypothalamus, pancreas, ovaries and testes are also glands. January 25, 2012 Slide 4 Many glands in your body secrete hormones into the blood • The Pituitary gland in the based of your skull releases hormones which control your blood pressure, your excretory system and other glands • The Thyroid gland in your neck controls your bone growth rate and metabolism • The adrenal gland above your kidneys release adrenalin if you get excited. • Endocrine glands are everywhere. January 25, 2012 Slide 5 DISEASES OF THE ENDOCRINE SYSTEM Let’s look at some of the diseases of the endocrine system and how they affect the human body. Dwarfism: Results when the pituitary gland does not produce enough growth hormone. Deficiency in children results in dwarfism. Dwarfism features · short stature · growth failure. Causes: · mutations of genes, involving the pituitary gland. · Damage to the pituitary from injury, surgery or disease January 25, 2012 Slide 6 Gigantism Gigantism occurs when the pituitary gland produces too much growth hormone. January 25, 2012 Slide 7 January 25, 2012 Slide 7A Radhouane Charbib born October 27, 1968) was recognized by the Guinness Book of Records as the tallest living man,[1] until January 15, 2005 when Bao Xishun was measured at Chifeng City Hospital, Inner Mongolia, China, and recorded as being 2 millimeters taller. Thank you Levi for sharing your Guinness Book of World records 2004 from which this picture was taken. January 25, 2012 Gigantism When too much growth hormone is produced after adulthood, abnormalities in the facial bones is common.. The picture below is the same woman as she got older. Slide 8 January 25, 2012 Slide 9 Hypothyroidism Too little thyroid hormone • Common Symptoms Low energy, fatigue, depression Feeling cold Muscle pain Slowed thinking Constipation Weight gain Dry and brittle skin, hair, nails January 25, 2012 Slide 10 HYPOTHYROID BEFORE AND AFTER The photographs show how the patients’ appearance dramatically changed after treatment with natural thyroid hormone. Notice how treatment resolved the puffy face, the puffy eyes, the thinning hair, and even the lips naturally turn up. Before treatment After treatment January 25, 2012 Slide 11 Hypothyroidism in Dogs January 25, 2012 Slide 12 Hyperthyroidism Too much thyroid hormone • Common Symptoms Shaking, nervousness, irritability Feeling hot A rapid, irregular heartbeat Muscle weakness, fatigue More frequent bowel movements Weight loss Hair loss January 25, 2012 Slide 13 Hyperthyroidism Too much thyroid hormone Enlarged thyroid gland (known as goiter) bulging eyes January 25, 2012 Slide 14 Goiter is an enlarged thyroid gland that can be caused by a lack of iodine in the diet. Iodine is added to salt to help prevent goiter This woman had surgery to remove the thyroid gland. January 25, 2012 Slide 15 Adrenal Glands When faced with a stressful situation the adrenal glands secrete adrenaline which · increases the heart rate and breathing rate. · · This give more oxygen and glucose to the cells so they can produce more energy. January 25, 2012 Slide 16 The extra energy allows your body to be able to ……. January 25, 2012 Slide 17 The hormone insulin comes from the pancreas, a gland located just behind the stomach. • When you eat, your pancreas secretes insulin into your bloodstream. • As insulin circulates, it acts like a key by unlocking microscopic doors that allow sugar to enter your cells. • Insulin lowers the amount of sugar in your bloodstream. As your blood sugar level drops, so does the secretion of insulin from your pancreas. • Your liver acts as a glucose storage and manufacturing center. When you haven't eaten in a while, for example, your liver releases stored glucose to keep your glucose level within a normal range. January 25, 2012 Diabetes occurs when the pancreas does not produce enough insulin. The cells do not get enough glucose and the blood sugar levels get very elevated. Diabetes symptoms · · · · · · · · Increased thirst frequent urination Extreme hunger Unexplained weight loss Fatigue Blurred vision Slow-healing sores Frequent infections January 25, 2012 Slide 19 Testing for glucose in the blood January 25, 2012 Slide 20 Reaction time test: Remember that the nervous system reacts much faster than the endocrine system. Test your own reaction time. To begin, click on the picture below. Records 0.03 sec BB DD 0.02 sec KF, HS, JA 0.01 sec DE, JF, MM, Tw, ST, MW