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When Hardy-Weinberg predictions about future generations are… When H-W equation does NOT accurately predict gene frequencies for generation after generation, it is safe to assume that the population is evolving. Populations may be evolving due to any or all of the following 5 forces: 1. Mutations (flaws in replication leading to new genes) http://perso.wanadoo.fr/corine.lundqvist/lundehund6toes.jpg 2. Migration (new individuals bringing new genes) -animals can move to new areas, but so can pollen… http://pollen.utulsa.edu/Image3.jpg 3. Genetic Drift •changes in the gene pool of a small population due to chance •Leads to a loss of alleles and less variation http://www.biol.andrews.edu/fb/spring/chap.23/2305.jpg Ex: ”Bottleneck Effect” Due to disasters like earthquakes, floods, fires, over-hunting, or diseases http://www.si.edu/archives/thisday/ august/cheetah.jpg -Cheetahs appear to have gone through a bottle-neck event Genetic Drift (cont.) Ex: Founder Effect: when few individuals start a new, isolated population. Their alleles (good or bad) become common. Microcephaly in Old Order Amish people of Lancaster County, Pennsylvania -61 babies in last 40 years http://www.nlm.nih.gov/medlineplus/ ency/images/ency/fullsize/17256.jpg Huntington’s Disease in Type O blood in South Venezuela and Central American -most descended from Indians Maria Concepción Soto http://anthro.palomar.edu/synthetic/synth_5.htm 4. Nonrandom Mating (certain genotypes mate more often than expected if mating is random) -mating with similar genotypes -inbreeding http://www.oceanwanderers.com/BlueGoose.6755.JPG Snow geese come in two colors: blue and white. They prefer to mate with birds of the same color. Leads to inflated rates of homozygous genotypes. 5. Natural Selection (individuals of certain genotypes leave behind more offspring than other genotypes) http://library.thinkquest.org/C003763/images/origin/finches.jpg Darwin’s Finches (Galapagos Islands) What advantage does it give a species to have variation in genes? Why not just have the “best” gene for all offspring? It gives a species a way to change (adapt) if necessary. “Evolutionary spurts occur when a population is stressed by a change in the environment, migration to a new place, or a drastic change in the genome. When challenged with a new set of problems, a population either adjusts through natural selection or it becomes extinct. The fossil record indicates that extinction is the more common outcome. Those populations that do survive crises often change enough to become a new species…” Biology, Campbell, p450