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Institut Curie | Enseignements | Cours médical et paramédical | 15 March 2016 ACCUEIL » ENSEIGNEMENTS ET FORMATIONS COURS INTERNATIONAL 1ST COURSE ON GENOME INSTABILITY AND HUMAN DISEASE 2016 Theme of course: Genome Instability and Human diseases Description of course: Genome instability is a hallmark of cancer cells but also a cause of genetic diseases in humans. Our understanding of the causal relationships between genome instability and the development of human diseases rely on our knowledge of the fundamental mechanisms of DNA metabolism, including spatial genome organization to genome expression and regulation during development or in response to environmental stress. The dysfunctions of basic mechanisms linked to genome metabolism underlie human diseases including cancer. Organizers: A. Carreira, S. Lambert & Pr. S. Saule 20160509_programme.pdf Audience: Master students, PhDs, Postdoc fellows, and researchers. Conditions of selection: 30 seats available. Selection based on cover letter Application deadline: 15 March 2016 Location: - 9, 10, 11, 12 and 13 May 2016 : Amphithéâtre du Bat 111, Institut Curie, centre universitaire Paris Sud, 91405, Orsay. - 12 May 2016: Amphithéâtre de la BDD, Institut Curie, 75005, Paris. Results of selection: 1 April 2016 Registration fees: No registration fees are requested. Organizers: Aura Carreira Sarah Lambert Pr Simon Saule Contact: [email protected] Course objectives: - Gain knowledge of mechanisms ensuring genome stability, from fundamental molecular pathways (DNA replication, repair, transcription, genome organization) up to large scale approaches (molecular signature using NGS and proteomic). - Highlight how a research continuum, from basic research to clinical and translational research, provides opportunities to solve human health issues. Educational objectives: - Encourage the students to speak. Students will ensure the moderator role and introduce speakers + elevator speech Train students to the evaluation process by awarding themselves the poster price. Topics: - Basics mechanisms for maintaining genome stability (repair, replication, DNA damage signaling, spatial genome organization) - Dysfunction of these pathways in human diseases (cancer, aging, immunodeficiency). - Molecular signature of Genome Instability - The DNA Damage Response as anti-cancer therapeutic targets and tools for diagnostic/prognostic. Workshops: - Elevator speech - Poster Session - CRISPR Technologies Round table: Round table for career development Partners: Paris Sud Sponsors: Sigma SFC