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MESOTHERAPY in DERMATOLOGY
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Indications
z Hair:
Telogen effluvium
Androgenetic Alopecia
z Face :
Facial rejuvenation (wrinkles + Firming)
Facial pigmentation e.g. melasma.
Indications
z Body
Localised fat areas .
Cellulite.
Stretch marks.
How To Start
1.
2.
3.
4.
5.
Materials & protocols / indication.
Injection sites.
Injection Depths.
Needle size.
Machine.
Materials
Classified into :
z Principals(Major)
z Complementary(Minor)
TIP:
Mixture should contain 2-3 principals to
achieve satisfactory results(>90%).
Hair
z
Principals
Telogen
Effluvium
Biotin
Hair
(Vitamin H/B7)
Growth
Pantothenic
Stimulants
acid
(Vitamin B5)
Complementary
Pyridoxine
(Vitamin B6)
Zinc + Azelaic
acid
MV + MTE
Hair
z
AGA
Principals
Hair
Growth
Minoxidil
Stimulants
Finasteride
5-ARI
Dutasteride
Complementary
Zinc + Azelaic
acid
MesoHair Protocols
Telogen Effluvium
Androgenetic Alopecia
Biotin (P)
Dexenol(P)
MV + MTE (C)
Minoxidil(P) /
Dutasteride(P) +
Biotin(P)
Dexenol(P)
Zinc + Azelaic (C)
MesoHair
Injection sites & depths 1-2mm
Face MesoLift / MesoGlow
z Rejuvenation
(Major)
Proven to Stimulate collagen synthesis
Hyaluronic acid
z Amino acids
z Vitamin C
z Organic Silicium
z Fibronectin + Vegetal proteins (Collagen &
Elastin)
z Vitamin A
z
Face MesoLift / MesoGlow
z Rejuvenation
Glycolic acid
z Taurine
z XADN
z MV & MTE
z
(Complementary)
Major Firming
z
DMAE :
1. Potent firming acts quickly and lasts
long.
2. Acts in the neuromuscular union, as a
precursor of acetylcholine, the
neurotransmitter responsible for
muscular contraction, increasing the
overall tone of the skin.
z DMAE + Organic Silicium
MesoGlow Protocols
Glow
HA (P)
Lift (Firming)
HA (P)
Silorg (P)
Silorgamine = Silorg + DMAE (P)
Purascorbol / Vitamin C (P)
Puretinol / Vitamin A (P)
Xadenal (C)
Taurinox (C)
MesoGlow/Lift
Injection sites & depths 1-2mm
Face Pigmentation
Principals
z
MesoLighten
▼ Melanogenesis
Glutathione
Kojic
Vitamin C
Azelaic acid
Complementary
Glycolic acid
Tretinoin
MesoLighten Protocols
Kojic acid (P)
Azelaic acid (P)
Vitamin C (P)
Tretinoin (C)
Glutathione (P)
Kojic acid (P)
Vitamin C (P)
Glycolic acid (C)
MesoLighten
Injection sites & depths 1-2mm
Body
z Localized
Fat
z Cellulite
z Stretch
marks
Localized Fat
z LipoDissolve
= Injection Lipolysis
Localized Fat
IAAL
Injection Lipolysis
Mesotherapy
Deep 12mm
PPC + DOC (PCDC)
Hyaluronidase-CollagenaseArtichoke
Intermediate 6mm
(L-Carnitine-AminophyllineYohimbine- Artichoke)
2 - 4 mm
L-Carnitine
Aminophylline
Pentoxifylline
Effective complement
Phosphatidyl Choline (PPC)
z An
antioxidant derived from soy lecithin.
z PPC penetrates the adipocyte , breaks
down fat . Dissolved fat is carried
through bloodstream and excreted by
kidneys and bowel.(P)
z LipoDissolve + proper diet + Exercise.
Localized Fat/ Injection Lipolysis
Lipolytic Enhancers:
z Deoxycholate:
Bile salt(P).
z L-Carnitine: Enhances both lipolysis and
fatty acid oxidation(P)
z Artichoke: Direct lipolytic (P)
z Aminophylline , Caffeine & Xanthine(P)
z Hyaluronidase & Collagenase: PPC
enhancer Enzymes (C)
PPC + DOC
z
Detergent Effects of Sodium Deoxycholate Are a Major
Feature of an Injectable Phosphatidylcholine Formulation
Used for Localized Fat Dissolution.
Rotunda AM, Suzuki H, Moy RL, Kolodney MS. Dermatol Surg 2004;30:1001-8.
Division of Dermatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA.
Conclusions:
The phosphatidylcholine formula popularly used in subcutaneous
injections for fat dissolution works primarily as a detergent
causing nonspecific lysis of cell membranes. Our findings suggest
that sodium deoxycholate is the major active component
responsible for cell lysis.Thus,eliminating unwanted adipose
tissue.
Localized Fat/ Injection Lipolysis
Circulatory Enhancers:
z Yohimbine:Alpha2-adrenergic Blocker.
z Aminophylline &Pentoxiphylline: PDEI
Drainage Enhancers:
z Artichoke:Diuretic and stimulates
lymphatic drainage
Localized Fat/ Injection Lipolysis
Protocols
Phosphatidylcholine(P)
Deoxycholic Acid(P)
Vitamin complex
Alpha Lipoic Acid
Amino Acids
Phosphatidylcholine(P)
Deoxycholic Acid (P)
Taurine
Organic silicium
Phosphatidylcholine(P)
Deoxycholic Acid (P)
L-Carnintine
Aminophylline
Pantothenic Acid
LipoDissolve
Injection sites & depths12mm
Cellulite
z
Aesthetically cellulite is a problem
consisting of the visual presentation of
weakened and damaged fatty tissue and
connective fibrous tissue in the form of
bumps and dimples, commonly known as
“orange skin”.
Cellulite
Treatment must act in two different ways:
z on the fat (Lipolytic effect)
z on circulation (Venotonic effect + Drainage)
Cellulite
z Lipolytic:
L- Carnitine + Caffeine .
z Venostatic:
Rutin – Aminophylline –Pentoxiphylline.
z Drainage:
Artichoke.
Cellulite Protocols
z
z
z
z
z
z
L- Carnitine
Aminophylline
Pentoxiphylline
Yohimbine
DMAE
Procaine
All are Principals
z
z
z
z
z
z
L- Carnitine
Aminophylline
Pentoxiphylline
DMAE
Vitamin C
Procaine
Stretch Marks
The connective tissue, including collagen
and elastin, becomes increasingly
damaged until eventually causing the
formation of stretch marks.
Stretch Marks
Collagen Elastin Stimulating/ Restoring agents
Organic Silicium / Silorg
z Centella Asiatica
z Vegetal proteins + Fibronectin
z
Firming agents
z DMAE + Vitamin C
z DMAE + Idebenone.
MesoStretch Marks Protocols
Silorgamine =
Silorg + DMAE
z
z
z
z
Idebe =
Idebenone + DMAE
z
z
z
z
All are Principals
Centella Asiatica
Fibronectin
Vegetal Proteins
Vitamin C
DMAE
Silorg
Needle size
30/32 G x 4 mm
z 30/32 G x 6 mm
z 30/32 G x 12.7 mm
z
MesoGuns
Meso Doctor
Syringe Infusion Pump
Injection Techniques
z PAPULE:
1 to 2mm, with bevel upwards
z NAPPAGE:
2 to 4mm, angle of 30° to 60°
z POINT BY POINT:
deep injections, 4 to 12mm
Contraindications
Pregnancy, blood thinners, IDDM,
cancer patients, AIDS patients, coronary
artery heart disease or heart dysfunction,
People with arrhythmias, history of blood
clots or strokes, autoimmune diseases or
organ transplant recipients and skin
conditions including: herpes & psoriasis.
MESOPORATION
z Mesotherapy
------ Non invasvive
z No needles are required.
MESOPORATION
A new complex process utilizes the
skin's water based "channels" to allow
ionic drug solutions to penetrate into the
skin, via controlled "electroporation - like"
electrical pulses.
MESOPORATION
MESOPORATION
MESOPORATION
ADVANCED MOLE TRANSFER
AN
M
V
AD
EN
TS
For face and body treatment with
electroporaction and dermoabrasion
CE
ST
DM
ED I C AL I N
RU
MesoLighten
Injection sites & depths 1-2mm
MesoLighten
Injection sites & depths 1-2mm
MesoLighten
LipoDissolve
LipoDissolve
Injection sites & depths12mm
Cellulite
Cellulite
MesoCellulite
Injection sites & depths 2mm
MesoCellulite
MesoStretch Marks
Injection sites
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