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HCA PLT SESSION 2/7/2015 Anne Morton Explain how cancer cells start Explain how cells mutate Explain how cancer cells grow into tumours Changes in 1 cell or a group of cells Signals in cells missing or faulty Causes cells to grow & multiply Produces a tumour Some cancers start in blood cells and bone marrow Gene changes within cells DNA in our cells have 1000s of Genes Genes are coded messages telling the cells how to behave Genes control how cells divide and make new cells in a healthy body When this goes wrong it is called a mutation This happens when a gene is damaged, lost or copied twice 6 different mutations happen before a healthy cell becomes a cancer cell Many years for some damaged cells to grow into a cancer By chance when cells divide Cause external to the body like chemical in tobacco smoke Inherit faulty genes which can increase chances of getting cancer Genes can get damaged every day but cells are good at repairing them Over time damage builds up Age increases risk of cancers Benign Usually grow quite slowly Don't spread to other parts of the body Usually have a covering made up of normal cells Can be a problem if Grow very large Become uncomfortable or unsightly Press on other body organs Take up space inside the skull (brain tumour) Release hormones Made up of cancer cells. Usually grow faster than benign tumours Spread into and damage surrounding tissues May spread to other parts of the body in the bloodstream or though the lymph system to form secondary tumours. Spreading to other parts of the body is called metastasis Information on slides taken from http://www.cancerresearchuk.org/aboutcancer/what-is-cancer/how-cancers-gro