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L. Gonzalez F2013 Modified by DYH Acinetobacter baumannii • • • • Gram negative, coccobacillus, non-motile Found in soil and water Genome structure: – Single circular chromosome : 3,976,747 base pairs Cell structure and metabolism: – Cell membrane composition • Includes porins and efflux channels which contribute to antibiotic resistance • Responsive to environment conditions – Metabolism • Glucose non-fermentative • Oxidase negative • Aerobic bacteria http://www.cdc.gov/HAI/organisms/acinetobacter.html L. Gonzalez F2013 Modified by DYH Acinetobacter baumannii • Pathology: – Opportunistic pathogen in humans with compromised immune systems – Causes 2-10% of all Gram negative infections in the U.S. and Europe – Multidrug-resistant – About 63% of Acinetobacter is considered multidrug-resistant http://en.wikipedia.org/wiki/File:Flickr_-_The_U.S._Army_-_Soldiers_receive_treatment_for_IED_injuries.jpg
