Download Activity 3.1.7: Designer Genes: Industrial Application Genetic

Activity 3.1.7 – Designer Genes:
Industrial Application of Genetic
Modification
Introduction
Your team will design an industrial application of recombinant DNA technology and
genes for fluorescent proteins. Several mail order colors are available which include
green, red and blue fluorescence. The design of the proposed engineering must
improve the human condition and meet legal concerns of federal regulatory
agencies.
For example: A local biotechnology company is looking for an innovative company
logo that incorporates the latest advances in genetic technology. Specifically, they
request a design that demonstrates applications of recombinant DNA technology.
Equipment
 Computer
 Graphics programs
Procedure
Initially, your team must determine the basic application of the genetic engineering
project and then select the best organism(s) and approach. The application must
benefit living systems in some way. Determine the following:



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Application
Organism(s)
Vector (how will your gene get put into your organism)
Control of gene expression (just like sugar or ampicillin was our control)
DUE DAY 2:
Designer Gene Proposal
Provide a written proposal for your industrial application including:
 Thumbnail sketches of proposed designs.
 Genetic maps (i.e., plasmid map) of genes and operon involved.
 Approval application for regulatory agencies. Determine appropriate
contacts.
DUE DAY 3:
Project Lead The Way, Inc.
Copyright 2010
PLTW TM - BE – Unit 3 – Lesson 3.1 – Activity 3.1.7 – Designer Genes: Industrial Application of Genetic
Modification – Page 1
 An animoto presentation will be given covering the experimental design,
sketches, and application of genetic modification.
 Take pictures of your sketches and include them in your animoto
 Student teams will document results throughout with digital photos or
graphic animations which will be incorporated into a PowerPoint
presentation.
Conclusion
1. What controls gene expression?
DNA codes that then make proteins.
2. How are operons like power switches?
They turn the gene on and off.
3. What are the current applications of recombinant DNA technology?
Gene transformations, ways we use it today are to further resistance against things for
plans or to change gene expressions of things
4. What are the ethical considerations regarding genetic engineering?
Engineers have to ask the ethical question that they will be altering nature and forcing
things to go our way.
5. What are the regulatory issues related to genetic engineering?
Cloning and stem cell research, the regulating issues are based on ethics.
Project Lead The Way, Inc.
Copyright 2010
PLTW TM - BE – Unit 3 – Lesson 3.1 – Activity 3.1.7 – Designer Genes: Industrial Application of Genetic
Modification – Page 2